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Displaying 20 of 44 results for "PON2"
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  1. PON2_RAT UniProt:Swiss-Prot

    ID: Q6AXM8

    Description: Serum paraoxonase/arylesterase 2 Not cleaved Proton acceptor Calcium 1; catalytic Calcium

  2. Paraoxonase 2 Serves a Proapopotic Function in Mouse and Human Cells in Response to the Pseudomonas aeruginosa Q... ArrayExpress

    ID: E-GEOD-65935

    Description: expressed genes associated with cancer, including paraoxonase 2 (PON2), while DKONR MEF expressed little PON2. Adenovirus-mediated expression of human PON2 in DKONR MEF rendered them responsive to C12: ∆ψmito depolarized, Cacyto increased and caspase 3/7 activated. Human embryonic kidney 293T (HEK293T) cells expressed low levels of endogenous PON2, and these cells were also less responsive to C12. Overexpression of PON2, but not PON2-H114Q (no lactonase activity) in HEK293T cells caused them to become sensitive to C12. Because [C12] may reach high levels in biofilms in lungs of cystic fibrosis (CF) patients, PON2 lactonase activity may control ∆ψmito, Ca2+ release from the ER and apoptosis in CF airway epith...

  3. Paraoxonase 2 Serves a Proapopotic Function in Mouse and Human Cells in Response to the Pseudomonas aeruginosa Q... BioProject

    ID: PRJNA275438

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. PON2_MELGA UniProt:Swiss-Prot

    ID: Q91090

    Description: Serum paraoxonase/arylesterase 2 Not cleaved Proton acceptor Calcium 1; catalytic Calcium

  5. PON2_CHICK UniProt:Swiss-Prot

    ID: Q90952

    Description: Serum paraoxonase/arylesterase 2 Not cleaved Proton acceptor Calcium 1; catalytic Calcium

  6. Paraoxonase 2 Serves a Proapopotic Function in Mouse and Human Cells in Response to the Pseudomonas aeruginosa Q... OmicsDI

    ID: E-GEOD-65935

    Date Released: 02-21-2015

    Description: expressed genes associated with cancer, including paraoxonase 2 (PON2), while DKONR MEF expressed little PON2. Adenovirus-mediated expression of human PON2 in DKONR MEF rendered them responsive to C12: ∆ψmito depolarized, Cacyto increased and caspase 3/7 activated. Human embryonic kidney 293T (HEK293T) cells expressed low levels of endogenous PON2, and these cells were also less responsive to C12. Overexpression of PON2, but not PON2-H114Q (no lactonase activity) in HEK293T cells caused them to become sensitive to C12. Because [C12] may reach high levels in biofilms in lungs of cystic fibrosis (CF) patients, PON2 lactonase activity may control ∆ψmito, Ca2+ release from the ER and apoptosis in CF airway epith...

  7. PON2_CANLF UniProt:Swiss-Prot

    ID: P54832

    Description: Serum paraoxonase/arylesterase 2 Not cleaved Proton acceptor Calcium 1; catalytic Calcium

  8. The effects of 3OC12-HSL on global gene expression in primary human aortic endothelial cells (HAEC) ArrayExpress

    ID: E-GEOD-26295

    Description: that is critical for colonization and virulence. Paraoxonase 2 (PON2) hydrolyzes 3OC12-HSL and also protects against the effects of oxidized phospholipids thought to contribute to atherosclerosis. We now report the response of human aortic endothelial cells (HAEC) to 3OC12-HSL and oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (Ox-PAPC) in relation to PON2 expression. Methods and Results: Using expression profiling and network modeling, we identified the unfolded protein response (UPR), cell cycl...

  9. The effects of 3OC12-HSL on global gene expression in primary human aortic endothelial cells (HAEC). BioProject

    ID: PRJNA135057

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: that is critical for colonization and virulence. Paraoxonase 2 (PON2) hydrolyzes 3OC12-HSL and also protects against the effects of oxidized phospholipids thought to contribute to atherosclerosis. We now report the response of human aortic endothelial cells (HAEC) to 3OC12-HSL and oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (Ox-PAPC) in relation to PON2 expression. Methods and Results: Using expression profiling and network modeling, we identified the unfolded protein response (UPR), cell cycl...
  10. The effects of 3OC12-HSL on global gene expression in primary human aortic endothelial cells (HAEC). OmicsDI

    ID: E-GEOD-26295

    Date Released: 06-02-2014

    Description: that is critical for colonization and virulence. Paraoxonase 2 (PON2) hydrolyzes 3OC12-HSL and also protects against the effects of oxidized phospholipids thought to contribute to atherosclerosis. We now report the response of human aortic endothelial cells (HAEC) to 3OC12-HSL and oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (Ox-PAPC) in relation to PON2 expression. Methods and Results: Using expression profiling and network modeling, we identified the unfolded protein response (UPR), cell cycl...

  11. serum paraoxonase by directed evolution PDB

    ID: PDB:1V04

    Description: SERUM PARAOXONASE/ARYLESTERASE 1 (E.C.3.1.1.2, 3.1.8.1)

  12. Serum paraoxonase-1 by directed evolution with the K192Q mutation PDB

    ID: PDB:4Q1U

    Description: Serum paraoxonase/arylesterase 1 (E.C.3.1.1.2, 3.1.1.81, 3.1.8.1)

  13. Serum paraoxonase-1 by directed evolution at pH 6.5 in complex with 2-hydroxyquinoline PDB

    ID: PDB:3SRG

    Description: serum paraoxonase (E.C.3.1.1.2)

  14. Serum paraoxonase-1 by directed evolution at pH 6.5 PDB

    ID: PDB:3SRE

    Description: serum paraoxonase (E.C.3.1.1.2)

  15. Serum paraoxonase-1 by directed evolution with the H115W mutation PDB

    ID: PDB:4HHO

    Description: SERUM PARAOXONASE BY DIRECTED EVOLUTION

  16. Serum paraoxonase-1 by directed evolution with the H115Q and H134Q mutations PDB

    ID: PDB:4HHQ

    Description: SERUM PARAOXONASE BY DIRECTED EVOLUTION (E.C.3.1.1.2)

  17. PON3_RAT UniProt:Swiss-Prot

    ID: Q68FP2

    Description: Removed Serum paraoxonase/lactonase 3 Not cleaved Proton acceptor Calcium 1; catalytic Calcium 2 Calcium 2;...

  18. The Structure of a putative arylesterase from Agrobacterium tumefaciens str. C58 PDB

    ID: PDB:3DCI

    Description: Arylesterase

  19. PON3_RABIT UniProt:Swiss-Prot

    ID: Q9BGN0

    Description: Removed Serum paraoxonase/lactonase 3 Not cleaved Proton acceptor Calcium 1; catalytic Calcium 2 Calcium 2;...

  20. Round 18 Arylesterase Variant of Phosphotriesterase with Bound Transition State Analog PDB

    ID: PDB:4E3T

    Description: Phosphotriesterase (E.C.3.1.8.1)


Displaying 20 of 44 results for "PON2"