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Displaying 20 of 2,484 results for "PMEL"
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  1. Pmel CD8+ stim 1 vs. stim 2 BioProject

    ID: PRJNA91639

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Crystal structure of HLA-DR4 bound to GP100 peptide PDB

    ID: PDB:4IS6

    Description: patibility antigen, DRB1-4 beta chain, Melanocyte protein PMEL...

  3. Studies in a murine B16 melanoma model show that persistent antigen at vaccination sites induces CD8+ T cell sequestration, dysfunction and deletion OmicsDI

    ID: E-GEOD-43929

    Date Released: 06-02-2014

    Description: studied immune responses in mice vaccinated with gp100 peptide emulsified in incomplete Freund's adjuvant (IFA), commonly used in clinical cancer vaccine trials. After gp100 peptide/IFA vaccination, tumor-specific CD8+ T cells (adoptively trans...

  4. Studies in a murine B16 melanoma model show that persistent antigen at vaccination sites induces CD8+ T cell sequestration, dysfunction and deletion ArrayExpress

    ID: E-GEOD-43929

    Description: studied immune responses in mice vaccinated with gp100 peptide emulsified in incomplete Freund's adjuvant (IFA), commonly used in clinical cancer vaccine trials. After gp100 peptide/IFA vaccination, tumor-specific CD8+ T cells (adoptively trans...

  5. H-2Db complex with human gp100 PDB

    ID: PDB:3CC5

    Description: -microglobulin, nonameric peptide from Melanocyte protein Pmel 17...

  6. Real-time quantitative PCR analysis for miRNA in mouse CD8+ pMel-1 T cells BioProject

    ID: PRJNA259740

    Keywords: Other

    Access Type: download

  7. Crystal structure of Modified Melanoma Antigen gp100(209-T2M) Bound to Human Class I MHC HLA-A2 PDB

    ID: PDB:1TVH

    Description: chain/Beta-2-microglobulin/epitope of Melanocyte protein Pmel 17...

  8. Mus musculus strain:PMEL-1 TCR transgenic C57BL/6 : Mus musculus strain:PMEL-1 TCR transgenic C57BL/6 Genome sequencing BioProject

    ID: PRJNA238124

    Keywords: genome sequencing

    Access Type: download

    dataset.description: The pmel-1 transgenic mouse has been extensively employed as a model system to study the mechanisms of tumor immunology, CD8+ T cell di...
  9. Murine CD8+ Pmel Lymphocytes IL-2 vs. IL-15 BioProject

    ID: PRJNA91983

    Keywords: Transcriptome or Gene expression

    Access Type: download

  10. Cross-talk between 4-1BB and TLR1-TLR2 signaling in CD8+ T cells regulates TLR2’s costimulatory effects OmicsDI

    ID: E-GEOD-79475

    Date Released: 06-18-2016

    Description: ed and unstimulated T cell receptor transgenic ‘pmel’ and MyD88-/-pmel CD8+ T cells and identified changes in the expression levels of several TNF family members. In particular, TLR-stimulation increased 4-1BB levels in pmel but not in MyD88-/-pmel T cells. A link between 4-1BB and TLR1-TLR2 signaling in CD8+ T cells was highlighted by in fact that 4-1BB-/- T cells exhibited suboptimal responses to TLR1-TLR2 agonist, but responded normally to CD28 or OX40 costimulation. Moreover...

  11. Cross-talk between 4-1BB and TLR1-TLR2 signaling in CD8+ T cells regulates TLR2’s costimulatory effects ArrayExpress

    ID: E-GEOD-79475

    Description: ed and unstimulated T cell receptor transgenic ‘pmel’ and MyD88-/-pmel CD8+ T cells and identified changes in the expression levels of several TNF family members. In particular, TLR-stimulation increased 4-1BB levels in pmel but not in MyD88-/-pmel T cells. A link between 4-1BB and TLR1-TLR2 signaling in CD8+ T cells was highlighted by in fact that 4-1BB-/- T cells exhibited suboptimal responses to TLR1-TLR2 agonist, but responded normally to CD28 or OX40 costimulation. Moreover...

  12. Pmel CD8+ stim 1 vs. stim 2 ArrayExpress

    ID: E-GEOD-2348

    Description: Repeat experiments of CD8+ pmel effector cells following one and two rounds of restimulation

  13. Crystal structure of Melanoma Antigen gp100(209-217) Bound to Human Class I MHC HLA-A2 PDB

    ID: PDB:1TVB

    Description: chain/Beta-2-microglobulin/epitope of Melanocyte protein Pmel 17...

  14. Pmel CD8+ stim 1 vs. stim 2 OmicsDI

    ID: E-GEOD-2348

    Date Released: 03-27-2012

    Description: Repeat experiments of CD8+ pmel effector cells following one and two rounds of restimulation

  15. Expression data for naïve IL-2 and IL-12 primed Pmel-1 CD8+ T-cells BioProject

    ID: PRJNA128523

    Keywords: Transcriptome or Gene expression

    Access Type: download

  16. Studies in a murine B16 melanoma model show that persistent antigen at vaccination sites induces CD8+ T cell sequestration, dysfunction and deletion BioProject

    ID: PRJNA188175

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: studied immune responses in mice vaccinated with gp100 peptide emulsified in incomplete Freund's adjuvant (IFA), commonly used in clinical cancer vaccine trials. After gp100 peptide/IFA vaccination, tumor-specific CD8+ T cells (adoptively trans...
  17. Cross-talk between 4-1BB and TLR1-TLR2 signaling in CD8+ T cells regulates TLR2’s costimulatory effects BioProject

    ID: PRJNA315950

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ed and unstimulated T cell receptor transgenic ‘pmel’ and MyD88-/-pmel CD8+ T cells and identified changes in the expression levels of several TNF family members. In particular, TLR-stimulation increased 4-1BB levels in pmel but not in MyD88-/-pmel T cells. A link between 4-1BB and TLR1-TLR2 signaling in CD8+ T cells was highlighted by in fact that 4-1BB-/- T cells exhibited suboptimal responses to TLR1-TLR2 agonist, but responded normally to CD28 or OX40 costimulation. Moreover...
  18. Expression data for naïve IL-2 and IL-12 primed Pmel-1 CD8+ T-cells OmicsDI

    ID: E-GEOD-22443

    Date Released: 06-10-2011

    Description: ypically and functionally similar to IL-12 primed Pmel-1 T-cells. These results highlight IL-12 as an important mediator of CD8+ T-cell effector function and anti-tumor immunity. We primed Pmel-1 TCR transgenic CD8+ T-cells with cognate antigen and either IL-2 or IL-12 and compared their gene expression profiles. This was used to identify pathways or genes necessary for anti-tumor activity in vivo. RNA was isolated from Pmel-1 T-cells primed with antigen and cytokine for 6 days and hybridized to Affymetrix arrays....

  19. Melanomas enhance metastasis and resist BRAF-therapy through regulation of the scaffold protein FHL2 after loss of differentiation markers BioProject

    ID: PRJNA246423

    Keywords: Transcriptome or Gene expression

    Access Type: download

  20. PMEL_MOUSE UniProt:Swiss-Prot

    ID: Q60696

    Description: Melanocyte protein PMEL M-alpha M-beta Lumenal Helical Cytoplasmic PKD 1 2 3 4 5 6 7 7 X 13 AA approximate tandem repeats, ...


Displaying 20 of 2,484 results for "PMEL"