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Displaying 20 of 65 results for "PLAC4"
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  1. PLAC4_HUMAN UniProt:Swiss-Prot

    ID: Q8WY50

    Description: Placenta-specific protein 4 (in Ref. 1; AAG23170)

  2. Placenta environment induces the differentiation of macrophages into multinucleated giant cells BioProject

    ID: PRJNA141401

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Performance Evaluation of Commercial miRNA Expression Array Platforms BioProject

    ID: PRJNA120787

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ereas the Illumina and Exiqon platforms were more specific. Furthermore, the data analysis approach had a large impact on the performance, predominantly by improving precision. Overall design: Performance of four (4) commercially available miRNA platforms was evaluated using 7 placenta samples spiked with synthetic microRNA spikes (in Latin-square design) absent in placenta. Platforms were primarily ...
  4. Placenta environment induces the differentiation of macrophages into multinucleated giant cells OmicsDI

    ID: E-GEOD-29575

    Date Released: 05-13-2014

    Description: A major population of placenta macrophages represented throughout the pregnancy consists of CD14+ macrophages, but their characteristics remain badly und...

  5. Placenta environment induces the differentiation of macrophages into multinucleated giant cells ArrayExpress

    ID: E-GEOD-29575

    Description: A major population of placenta macrophages represented throughout the pregnancy consists of CD14+ macrophages, but their characteristics remain badly und...

  6. Peg3 mutational effects on reproduction and placenta-specific gene families BioProject

    ID: PRJNA219071

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Female- and male-specific transcriptomic and epigenetic placental signatures in response to a maternal high fat diet in mice BioProject

    ID: PRJNA141421

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Female- and male-specific transcriptomic and epigenetic placental signatures in response to a maternal high fat diet in mice ArrayExpress

    ID: E-GEOD-29585

    Description: mes differing depending on the child’s sex. The placenta is involved in the programming of obesity, type 2 diabetes and cardiovascular disease. Sex-specific adaptation of the placenta may be central to the differences in fetal gro...

  9. Arid3a is required for mammalian placenta development BioProject

    ID: PRJNA316574

    Keywords: Transcriptome or Gene expression

    Access Type: download

  10. Performance Evaluation of Commercial miRNA Expression Array Platforms ArrayExpress

    ID: E-GEOD-19248

    Description: ereas the Illumina and Exiqon platforms were more specific. Furthermore, the data analysis approach had a large impact on the performance, predominantly by improving precision. Performance of four (4) commercially available miRNA platforms was evaluated using 7 placenta samples spiked with synthetic microRNA spikes (in Latin-square design) absent in placenta. Platforms were primarily evaluated for ac...

  11. Organ-specific gene expression changes in the fetal liver and placenta in response to maternal folate depletion ArrayExpress

    ID: E-MTAB-3940

    Description:  mg folic acid/kg or 0.4 mg folic acid/kg for 4 weeks before mating and throughout pregnancy. At 17.5 day gestation, genome-wide gene expression in fetal liver and placenta of male offspring was measured by microarray analysis. In the fetal liver, 989 genes (555 up-regulated, 434 down-regulated) were expressed differentially in response to maternal folate depletion, with 460 genes expressed differentially (250 up-regulated, 255 down-regulated) in the placenta. Only 25 differentially expressed genes were common between organs, revealing that maternal folate intake during pregnancy influences fetal gene expression in a highly organ specific manner which, we propose, reflects prioritised protection of essential organ-specific functions....

  12. Gene expression differences in yolk sac tissue between wild-type and Zfp36l3 knockout mice BioProject

    ID: PRJNA275943

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: The ZFP36L3 protein is a rodent-specific, placenta- and yolk sac-specific member of the tristetraprolin (TTP) family of CCCH ...
  13. Arid3a is required for mammalian placenta development ArrayExpress

    ID: E-GEOD-79638

    Description: ypes in the junctional and labyrinth zones of the placenta. Conventional Arid3a knockout embryos suffer restricted intrauterine growth with sever defects in placental structural organization. Arid3a null placentas show aberrant expression of subtype-specific markers as well as significant alteration in inflammatory response-related genes, cytokines and chemokines. We provide evidence that BMP4-mediated induction of trophoblast stem (TS)-like cells from human induced pluripotent (iPS) stem cells results in ARID3A upregulation and cy...

  14. Peg3 mutational effects on reproduction and placenta-specific gene families ArrayExpress

    ID: E-GEOD-50818

    Description: rding to genome-wide expression analyses, several placenta-specific gene families are de-repressed in the brain of Peg3 heterozygous embryos, including prolactin, cathepsin and carcinoembryonic antigen cell adhesion molecule (Ceacam) families. The observed de-repression is more pronounced in females than in males. The de-repression of several members of these gene families is observed even in the adult brain, suggesting potential defects in epigenetic setting of the placenta-specific gene families in the Peg3 mutants. Overall, these results indicate that Peg3 likely controls the transcription of several placenta-specific gene families, and furth...

  15. Peg3 mutational effects on reproduction and placenta-specific gene families OmicsDI

    ID: E-GEOD-50818

    Date Released: 09-12-2014

    Description: rding to genome-wide expression analyses, several placenta-specific gene families are de-repressed in the brain of Peg3 heterozygous embryos, including prolactin, cathepsin and carcinoembryonic antigen cell adhesion molecule (Ceacam) families. The observed de-repression is more pronounced in females than in males. The de-repression of several members of these gene families is observed even in the adult brain, suggesting potential defects in epigenetic setting of the placenta-specific gene families in the Peg3 mutants. Overall, these results indicate that Peg3 likely controls the transcription of several placenta-specific gene families, and furth...

  16. Mid-gestational gene expression profile in placenta and link to pregnancy complications BioProject

    ID: PRJNA165681

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. Female- and male-specific transcriptomic and epigenetic placental signatures in response to a maternal high fat diet in mice OmicsDI

    ID: E-GEOD-29585

    Date Released: 04-11-2012

    Description: mes differing depending on the child’s sex. The placenta is involved in the programming of obesity, type 2 diabetes and cardiovascular disease. Sex-specific adaptation of the placenta may be central to the differences in fetal gro...

  18. Organ-specific gene expression changes in the fetal liver and placenta in response to maternal folate depletion OmicsDI

    ID: E-MTAB-3940

    Date Released: 06-14-2016

    Description:  mg folic acid/kg or 0.4 mg folic acid/kg for 4 weeks before mating and throughout pregnancy. At 17.5 day gestation, genome-wide gene expression in fetal liver and placenta of male offspring was measured by microarray analysis. In the fetal liver, 989 genes (555 up-regulated, 434 down-regulated) were expressed differentially in response to maternal folate depletion, with 460 genes expressed differentially (250 up-regulated, 255 down-regulated) in the placenta. Only 25 differentially expressed genes were common between organs, revealing that maternal folate intake during pregnancy influences fetal gene expression in a highly organ specific manner which, we propose, reflects prioritised protection of essential organ-specific functions....

  19. Mid-gestational gene expression profile in placenta and link to pregnancy complications ArrayExpress

    ID: E-GEOD-37901

    Description: t (FDR P<0.05) expressional peak in mid-gestation placenta for ten genes: BMP5, CCNG2, CDH11, FST, GATM, GPR183, ITGBL1, PLAGL1, SLC16A10, STC1. A central hypothesis of our study states that the aberrant expression of genes characteristic to mid-gestation placenta may contribute to affected fetal growth, maternal preeclampsia (PE) or gestational diabetes (GD). The gene STC1 coding for Stanniocalcin 1 (STC1) was identified with a sharp placental expressional peak in mid-gestation, increased mRNA levels at term and significantly elevated STC1 protein levels in post-partum maternal plasma in all pregnancy complications. The highest STC1 levels were identified in women, who developed simultaneously PE and delivered an SGA baby (median 731 vs 418 pg/ml in con...

  20. Mid-gestational gene expression profile in placenta and link to pregnancy complications OmicsDI

    ID: E-GEOD-37901

    Date Released: 05-21-2012

    Description: t (FDR P<0.05) expressional peak in mid-gestation placenta for ten genes: BMP5, CCNG2, CDH11, FST, GATM, GPR183, ITGBL1, PLAGL1, SLC16A10, STC1. A central hypothesis of our study states that the aberrant expression of genes characteristic to mid-gestation placenta may contribute to affected fetal growth, maternal preeclampsia (PE) or gestational diabetes (GD). The gene STC1 coding for Stanniocalcin 1 (STC1) was identified with a sharp placental expressional peak in mid-gestation, increased mRNA levels at term and significantly elevated STC1 protein levels in post-partum maternal plasma in all pregnancy complications. The highest STC1 levels were identified in women, who developed simultaneously PE and delivered an SGA baby (median 731 vs 418 pg/ml in con...


Displaying 20 of 65 results for "PLAC4"