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Displaying 20 of 80 results for "PIK3R3"
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  1. PI3R5_XENLA UniProt:Swiss-Prot

    ID: Q6INI0

    Description: Phosphoinositide 3-kinase regulatory subunit 5 Heterodi...

  2. PI3R5_PIG UniProt:Swiss-Prot

    ID: O02696

    Description: Phosphoinositide 3-kinase regulatory subunit 5 Heterodi...

  3. PIRK5_CHICK UniProt:Swiss-Prot

    ID: Q5ZIB8

    Description: Phosphoinositide 3-kinase regulatory subunit 5 Heterodi...

  4. P395S mutant of the p85 regulatory subunit of the N-terminal src homology 2 domain of PI3-Kinase complexed to a peptide derived from PDGFr PDB

    ID: PDB:1OO4

    Description: Phosphatidylinositol 3-kinase regulatory alpha subunit/8-mer peptide from PDGFr...

  5. P395S mutant of the p85 regulatory subunit of the N-terminal src homology 2 domain of PI3-Kinase PDB

    ID: PDB:1OO3

    Description: Phosphatidylinositol 3-kinase regulatory alpha subunit

  6. CRYSTAL STRUCTURE OF THE PI3-KINASE P85 N-TERMINAL SH2 DOMAIN PDB

    ID: PDB:2IUG

    Description: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT

  7. CRYSTAL STRUCTURE OF THE PI3-KINASE P85 N-TERMINAL SH2 DOMAIN IN COMPLEX WITH PDGFR PHOSPHOTYROSYL PEPTIDE PDB

    ID: PDB:2IUI

    Description: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT, PDGFR PHOSPHOTYROSYL PEPTIDE...

  8. Whole Genome Sequencing Informs Therapeutic Selection for Pancreatic Cancer ArrayExpress

    ID: E-GEOD-61502

    Description: ned druggable oncogenes (ERBB2, MET, FGFR1, CDK6, PIK3R3, and PIK3CA), but at low individual frequency. Genomic instability co-segregated with inactivation of DNA maintenance genes (BRCA1, BRCA2, PALB2 or RPA1), and a mutational signature of DNA damage repair deficiency. This subgroup was associated with response to platinum-based therapy and defines candidate biomarkers of therapeutic responsiveness. DNA was assayed using Illumina SNP BeadChips as per manufacturer’s instructions (Illumina, San Diego CA) (HumanOmni1-Quad or HumanOmni2.5-8 BeadChips). SNP arrays were scanned and data was processed using the Genotyping module (v1.8.4) in Genomestudio v2010.3 (Illumina, San Diego CA) to calculate B-allele frequencies (BAF) and logR values. GenoCN4 and GAP5 were used to call somatic regions of copy number change – gain, loss ...

  9. A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyp... ArrayExpress

    ID: E-GEOD-74729

    Description: f e.g. genes encoding SPRY2, SPRY4, DUSP6, CCND1, PIK3R3, FGFR1, EPHA4, MCL1, and IGF1R was down-regulated, whereas expression of PDGFC, VEGFC, ABCB9 and KITLG was increased. Conclusions: Our study reports several differentially expressed genes which may contribute to vemurafenib resistance in A375 tumor bearing mice RNA sequencing of genes expressed in A375 tumors bearing mice treated with vemurafenib until in vivo resistance appeared vs. untreated A375 tumors...

  10. p55 and p75 tumor necrosis factor receptor double KO and systemic lupus erythematosis BioProject

    ID: PRJNA110537

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. ORF3_HEVME UniProt:Swiss-Prot

    ID: Q03499

    Description: AMBP/bikunin Interaction with host SRC, HCK, FYN, PIK3R3 and GRB2 Cys-rich Pro-rich...

  12. ORF3_HEVCT UniProt:Swiss-Prot

    ID: Q9IVZ7

    Description: AMBP/bikunin Interaction with host SRC, HCK, FYN, PIK3R3 and GRB2 Cys-rich Pro-rich...

  13. Mediating effects of miR-155 on the FceRI signaling responses of mast cells BioProject

    ID: PRJNA242260

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: iR-155 regulates negatively the expression of the regulatory subunits of the kinase PI3Kgamma, Pik3r5 (p101) and Pik3r6 (p84, p87PIKAP), involved in Ca+ influx and degranulation. Overall design: Total RNA from 3 independent cultures of WT and miR-155-/- BMMC treated with anti-DNP IgE and 20 ng/ml DNP-HSA for 1hr were used to performed gene expression analysis using the Affymetrix Genechip® Mouse Gene 1.0 ST...
  14. P55G_MOUSE UniProt:Swiss-Prot

    ID: Q64143

    Description: Phosphatidylinositol 3-kinase regulatory subunit gamma SH2 1 SH2 2 Phosphoty...

  15. P55G_BOVIN UniProt:Swiss-Prot

    ID: O46404

    Description: Phosphatidylinositol 3-kinase regulatory subunit gamma SH2 1 SH2 2 Phosphoty...

  16. A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyp... BioProject

    ID: PRJNA301353

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. Mediating effects of miR-155 on the FceRI signaling responses of mast cells ArrayExpress

    ID: E-GEOD-56030

    Description: iR-155 regulates negatively the expression of the regulatory subunits of the kinase PI3Kgamma, Pik3r5 (p101) and Pik3r6 (p84, p87PIKAP), involved in Ca+ influx and degranulation. Total RNA from 3 independent cultures of WT and miR-155-/- BMMC treated with anti-DNP IgE and 20 ng/ml DNP-HSA for 1hr were used to performed gene expression analysis using the Affymetrix Genechip® Mouse Gene 1.0 ST...

  18. Whole Genome Sequencing Informs Therapeutic Selection for Pancreatic Cancer BioProject

    ID: PRJNA261329

    Keywords: Variation

    Access Type: download

    dataset.description: ned druggable oncogenes (ERBB2, MET, FGFR1, CDK6, PIK3R3, and PIK3CA), but at low individual frequency. Genomic instability co-segregated with inactivation of DNA maintenance genes (BRCA1, BRCA2, PALB2 or RPA1), and a mutational signature of DNA damage repair deficiency. This subgroup was associated with response to platinum-based therapy and defines candidate biomarkers of therapeutic responsiveness. Overall design: DNA was assayed using Illumina SNP BeadChips as per manufacturer’s instructions (Illumina, San Diego CA) (HumanOmni1-Quad or HumanOmni2.5-8 BeadChips). SNP arrays were scanned and data was processed using the Genotyping module (v1.8.4) in Genomestudio v2010.3 (Illumina, San Diego CA) to calculate B-allele frequencies (BAF) and logR values. GenoCN4 and GAP5 were used to call somatic regions of copy number change...
  19. Solution structure of the erythroid p55 PDZ domain PDB

    ID: PDB:2EV8

    Description: 55 kDa erythrocyte membrane protein

  20. Structural Basis of Histone H4 Recognition by p55 PDB

    ID: PDB:3C9C

    Description: Chromatin assembly factor 1 p55 subunit, Histone H4


Displaying 20 of 80 results for "PIK3R3"