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Displaying 20 of 1,232 results for "PIK3CA"
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  1. Targeting β-catenin overcomes resistance to MEK inhibitor in PIK3CA mutant colon cancer OmicsDI

    ID: E-GEOD-71981

    Date Released: 08-20-2015

    Description: d attractive targets for cancer therapy. However, PIK3CA mutation, which commonly co-occurs with KRAS mutation, offered resistance to MEK inhibitor through activation of PI3K-AKT signaling. We identified a gene that cooperates with MEK inhibitors to forcefully treat

  2. Reactivation of multipotency by oncogenic PIK3CA induces breast tumor heterogeneity OmicsDI

    ID: E-GEOD-69290

    Date Released: 08-19-2015

    Description: different histological and molecular subtypes1-3. Pik3ca and p53 are the two most frequently mutated genes and are associated with different types of human breast cancers4. The cellular origin and the mechanisms leading to Pik3ca-induced tumour heterogeneity remain unknown. Here, we u...

  3. Proteomic Analysis of wild-type and PIK3CA mutant cell lines OmicsDI

    ID: MSV000079060

    Date Released:

    Description: Wild-type and PIK3CA mutant MCF10A cell lines were analyzed using shotgun proteomics to identify proteins that were altered by either 545K or H10...

  4. Gene expression profiling of Lgr5-creERT2/PIK3CA H1047R and K8-creERT2/PIK3CA H1047R-evoked mammary tumors BioProject

    ID: PRJNA256962

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Transcriptional data from yeast expressing mammalian PIK3CA BioProject

    ID: PRJNA255676

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Reactivation of multipotency by oncogenic PIK3CA induces breast tumor heterogeneity BioProject

    ID: PRJNA285089

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Gene expression profiles of PIK3CA knockdown by shRNA in lung cancer cells BioProject

    ID: PRJNA202993

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Transcription profiling by array of human estrogen receptor alpha positive breast tumors with and without PIK3CA mutations. OmicsDI

    ID: E-GEOD-22035

    Date Released: 05-01-2015

    Description: les in breast cancer development and maintenance. PIK3CA, coding PIK3 catalytic subunit, is the oncogene which shows the high frequency of gain-of-function mutations leading to the PI3K/AKT pathway activation in breast ca...

  9. Targeting β-catenin overcomes resistance to MEK inhibitor in PIK3CA mutant colon cancer BioProject

    ID: PRJNA292658

    Keywords: Proteome

    Access Type: download

  10. Oncogenic PIK3CA(H1047R) and CTNNB1(stab) in intestinal organoids BioProject

    ID: PRJNA363058

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. Common PIK3CA mutants and a novel 3’UTR mutation are associated with increased sensitivity to saracatinib BioProject

    ID: PRJNA151703

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. Gene expression data in estrogen receptor alpha positive breast tumors with and without PIK3CA mutations. BioProject

    ID: PRJNA128895

    Keywords: Transcriptome or Gene expression

    Access Type: download

  13. Knock-in of PIK3CA-H1047R into MCF-10A BioProject

    ID: PRJNA267827

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. Copy number variations in mouse mammary tumours driven by mutant Pik3ca^H1047R expression BioProject

    ID: PRJNA206990

    Keywords: Variation

    Access Type: download

  15. PIK3C A/B/D expression distinctions between LumA/LumB, and between PIK3CA mut/wt, breast cancer patients BioProject

    ID: PRJNA123107

    Keywords: Transcriptome or Gene expression

    Access Type: download

  16. Affymetrix SNP array data for mammary tumors that recurred after inactivation of the oncogenic PIK3CA-H1047R OmicsDI

    ID: E-GEOD-27691

    Date Released: 08-15-2011

    Description: Gain-of-function mutation of PIK3CA represents one of the most common oncogenic events in human malignancy, making PI3K an attractive target for cancer therapy....

  17. encing and Sanger sequencing for the detection of PIK3CA mutations in breast cancer... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3603116_D1

    Release Date: 12-14-2016

    Description: Genomic positions and the primer sequences. (XLS 45 kb)

  18. Reactivation of multipotency by oncogenic PIK3CA induces breast tumor heterogeneity ArrayExpress

    ID: E-GEOD-69290

    Description: different histological and molecular subtypes1-3. Pik3ca and p53 are the two most frequently mutated genes and are associated with different types of human breast cancers4. The cellular origin and the mechanisms leading to Pik3ca-induced tumour heterogeneity remain unknown. Here, we u...

  19. Affymetrix SNP array data for mammary tumors that recurred after inactivation of the oncogenic PIK3CA-H1047R BioProject

    ID: PRJNA138147

    Keywords: Variation

    Access Type: download

  20. Gene expression profiling of Lgr5-creERT2/PIK3CA H1047R and K8-creERT2/PIK3CA H1047R-evoked mammary tumors OmicsDI

    ID: E-GEOD-59872

    Date Released: 08-19-2015

    Description: This study examined the gene expression profile of mammary tumors derived from Lgr5- and K8-positive cell-of-origins Mammary tumors and reference mamm...


Displaying 20 of 1,232 results for "PIK3CA"