PHC2 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 21 results for "PHC2"
i
  1. SAM domain polymerization links subnuclear clustering of PRC1 to silencing OmicsDI

    ID: E-GEOD-37530

    Date Released: 06-21-2013

    Description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. Examination of H3K27me3 in wild type and the Phc2 mutant cells...

  2. SAM domain polymerization links subnuclear clustering of PRC1 to silencing (Ring1B ChIP-Seq) OmicsDI

    ID: E-GEOD-42801

    Date Released: 09-05-2013

    Description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. Examination of Ring1B in wild type and the Phc2 mutant cells...

  3. ULD complex PDB

    ID: PDB:2NA1

    Description: entity

    dataset.keywords.raw: phc2
  4. SAM domain polymerization links subnuclear clustering of PRC1 to silencing ArrayExpress

    ID: E-GEOD-37530

    Description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. Examination of H3K27me3 in wild type and the Phc2 mutant cells...

  5. SAM domain polymerization links subnuclear clustering of PRC1 to silencing (Ring1B ChIP-Seq) ArrayExpress

    ID: E-GEOD-42801

    Description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. Examination of Ring1B in wild type and the Phc2 mutant cells...

  6. SAM domain polymerization links subnuclear clustering of PRC1 to silencing (Affymetrix) OmicsDI

    ID: E-GEOD-37346

    Date Released: 06-02-2014

    Description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. Wild type and Phc2L307R/L307R MEFs were used for RNA extraction and hybridization on Affymetrix microarrays....

  7. SAM domain polymerization links subnuclear clustering of PRC1 to silencing BioProject

    ID: PRJNA167299

    Keywords: Epigenomics

    Access Type: download

    dataset.description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. Overall design: Examination of H3K27me3 in wild type and the Phc2 mutant cells...
  8. SAM domain polymerization links subnuclear clustering of PRC1 to silencing (Affymetrix) ArrayExpress

    ID: E-GEOD-37346

    Description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. Wild type and Phc2L307R/L307R MEFs were used for RNA extraction and hybridization on Affymetrix microarrays....

  9. SAM domain polymerization links subnuclear clustering of PRC1 to silencing (Ring1B ChIP-Seq) BioProject

    ID: PRJNA183216

    Keywords: Epigenomics

    Access Type: download

    dataset.description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. Overall design: Examination of Ring1B in wild type and the Phc2 mutant cells...
  10. SAM domain polymerization links subnuclear clustering of PRC1 to silencing (ChIP-chip) OmicsDI

    ID: E-GEOD-37526

    Date Released: 06-02-2014

    Description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. ChIP on chip analysis was carried out using the Mouse Promoter ChIP-on-chip Microarray Set (G4490A, Agilent, Palo Alto, Calif., USA). MEFs were subjected to ChIP assay...

  11. Solution NMR structure of FCS domain of Human Polyhomeotic Homolog 1 (HPH1) PDB

    ID: PDB:2L8E

    Description: Polyhomeotic-like protein 1

  12. Crystal structure of PHC3 SAM L967R PDB

    ID: PDB:4PZO

    Description: Polyhomeotic-like protein 3

  13. SAM domain polymerization links subnuclear clustering of PRC1 to silencing detected using expression data and ChIP experiments OmicsDI

    ID: E-GEOD-38154

    Date Released: 06-02-2014

    Description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. This SuperSeries is composed of the SubSeries listed below. Refer to individual Series ChIP on chip analysis was carried out using the Mouse Promoter ChIP-on-chip Mic...

  14. SAM domain polymerization links subnuclear clustering of PRC1 to silencing (Affymetrix) BioProject

    ID: PRJNA167300

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. Overall design: Wild type and Phc2L307R/L307R MEFs were used for RNA extraction and hybridization on Affymetrix microarrays....
  15. PHC2_XENLA UniProt:Swiss-Prot

    ID: Q4V7W5

    Description: Polyhomeotic-like protein 2 SAM FCS-type HD1

  16. SAM domain polymerization links subnuclear clustering of PRC1 to silencing (ChIP-chip) ArrayExpress

    ID: E-GEOD-37526

    Description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. ChIP on chip analysis was carried out using the Mouse Promoter ChIP-on-chip Microarray Set (G4490A, Agilent, Palo Alto, Calif., USA). MEFs were subjected to ChIP assay...

  17. SAM domain polymerization links subnuclear clustering of PRC1 to silencing detected using expression data and ChIP experiments ArrayExpress

    ID: E-GEOD-38154

    Description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. This SuperSeries is composed of the SubSeries listed below. Refer to individual Series ChIP on chip analysis was carried out using the Mouse Promoter ChIP-on-chip Mic...

  18. SAM domain polymerization links subnuclear clustering of PRC1 to silencing (ChIP-chip) BioProject

    ID: PRJNA167297

    Keywords: Epigenomics

    Access Type: download

    dataset.description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. Overall design: ChIP on chip analysis was carried out using the Mouse Promoter ChIP-on-chip Microarray Set (G4490A, Agilent, Palo Alto, Calif., USA). MEFs were subject...
  19. PRJNA167348 BioProject

    Access Type: download

    dataset.description: -to-tail polymerization property of SAM domain of Phc2 and likely Phc1. We show that Phc2-SAM polymerization limits the dynamic nature of PRC1, thereby promotes stable association of PRC1 with PcG target genes and contributes to their robust silencing. Our findings suggest a novel model by which SAM polymerization of Phc2 modulates the structural organization of PcG complexes to enable robust yet reversible PcG-mediated repression during development. This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series ChIP on chip analysis was carried out using the Mouse Promoter C...
  20. The structure of polycomb ULD complex PDB

    ID: PDB:5FR6

    Description: POLYCOMB COMPLEX PROTEIN BMI-1

    dataset.keywords: PHC2

Displaying 20 of 21 results for "PHC2"