PGRMC2 | bioCADDIE Data Discovery Index
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Displaying 15 of 15 results for "PGRMC2"
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  1. PGRC2_RAT UniProt:Swiss-Prot

    ID: Q5XIU9

    Description: Membrane-associated progesterone receptor component 2 H...

  2. PGRC2_MOUSE UniProt:Swiss-Prot

    ID: Q80UU9

    Description: Membrane-associated progesterone receptor component 2 H...

  3. Oscillochloris trichoides DG6 : Oscillochloris trichoides DG6 genome sequencing project. BioProject

    ID: PRJNA48647

    Keywords: Genome sequencing and assembly

    Access Type: download

  4. rat ovary in culture reveals interactions between progesterone and tumor necrosis factor-alpha in the regulation of primordial follicle assembly... ArrayExpress

    ID: E-GEOD-8238

    Description: e reproductive lifespan of a female. Previously, progesterone (P4) has been shown to inhibit follicle assembly, while tumor necrosis factor alpha (TNF-alpha) has been shown to promote the apoptosis that is necessary for follicle assembly. The current study examines how TNF-alpha and progesterone interact to regulate primordial follicle assembly. ...

  5. Interactions Between Progesterone and Tumor Necrosis Factor-alpha in the Regulation of Primordial Follicle Assembly BioProject

    ID: PRJNA101175

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Ligand and Target Discovery by Fragment-Based Screening in Human Cells BioProject

    ID: PRJNA355636

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ferentiation by engaging the poorly characterized membrane protein PGRMC2. Fragment-based screening in human cells thus provides an extensive proteome-wide map of protein ligandability and facilitates the coordinated discovery of bioactive small molecules and their molecular targets. Overall design: PolyA+ Rnaseq profilling of 3T3-L1 stably overexpressing Gfp or PGRMC2 treated with dmso and induced to differentiate into adipocytes. RNA samples were collected 24 hours after induction of differentiation....
  7. Enterobacter cloacae DG6 : Enterobacter cloacae DG6 genome sequencing BioProject

    ID: PRJNA302565

    Keywords: genome sequencing

    Access Type: download

  8. microRNA miR-142-3p induced expression changes in MDA-MB-231 breast cancer cells BioProject

    ID: PRJNA219097

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: regulation and cell motility. ROCK2, IL6ST, KLF4, PGRMC2 and ADCY9 were identified as additional targets in a subset of cell lines. Decreased matrigel invasiveness was associated with the miR-142-3p-induced expression changes. Confocal immunofluorescence microscopy, nanoscale atomic force microscopy and digital holographic microscopy revealed a change in cell morphology as well as a reduced cell volume and size. A more cortical actin distribution and a loss of membrane protrusions were observed in cells overexpressing miR-142-3p. Luciferase activation assays confirmed direct miR-142-3p-dependent regulation of the 3'-untranslated region of ITGAV and WASL. siRNA-mediated depletion of ITGAV andWASL resulted in a significant reduction of cellular invasiveness, highlighting the contribution of these factors to the miRNA-dependent invasion phenotype. While knockdown of WASL significantly redu...
  9. Crystal structure of human PGRMC1 cytochrome b5-like domain PDB

    ID: PDB:4X8Y

    Description: Membrane-associated progesterone receptor component 1

  10. Mechanisms of Chorioamnionitis-associated Preterm Birth: Interleukin 1 β inhibits Progesterone Receptor Expression in Decidual Cells BioProject

    ID: PRJNA275162

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. Analysis of the Pgrmc2-dependent transcriptome during murine adipocyte differentiation NURSA

    Keywords: WAT adipocytes 3T3-L1-derived

    Description: Mouse 3T3-L1 preadipocytes stably expressing Pgrmc2 or GFP were induced to differentiate into adipocytes for 24 h.

    ID: 10.1621/Yi4vVHiTW2

  12. Altered Gene Expression Profile in Ovarian Follicle in Rats Treated with Indomethacin and RU486 BioProject

    ID: PRJNA237063

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: l-known that indomethacin (the cyclooxygenase 1 & 2 inhibitor) and RU486 (or mifepristone, the progesterone receptor antagonist) block follicular ruptur...
  13. PGRN-RIKEN MA.27 Mayo Aromatase Inhibitor Musculoskeletal Adverse Events Study dbGaP

    ID: phs000210.v1.p1

    Description: MO. The primary tumor must have been ER and/or progesterone receptor positive. Patients were stratified by lymph node status at diagnosis, prior adjuvant chemotherapy, and trastuzumab use and were randomized to 5 years of adjuvant therapy with anastrozole or exemestane. The trial was activated on May 26, 2003, and reached its accrual objectives on July 31, 2008, after the randomization of 6827 North American patients, with the majority (79%) providing DNA and consent for genetic testing. Non-North American patients were also entered by the International Breast Cancer Study Group but they did not contribute DNA. From 2003 to December 21, 2004, patients also underwent a second randomization to celecoxib 400 mg twice daily or placebo but, after the entry of 1,622 patients, this treatment was discontinued because of reports of increased cardiovascular risk associated with celecoxib. Case Definition for Musculoskeletal Adverse Events Cases were defined to have ha...

    Study Types: Nested Case-Control

  14. PRJEB20432 BioProject

    Keywords: Genome sequencing

    Access Type: download

    dataset.description: Enterobacter cloacae DG6
  15. rat ovary in culture reveals interactions between progesterone and tumor necrosis factor-alpha in the regulation of primordial follicle assembly... OmicsDI

    ID: E-GEOD-8238

    Date Released: 03-27-2012

    Description: e reproductive lifespan of a female. Previously, progesterone (P4) has been shown to inhibit follicle assembly, while tumor necrosis factor alpha (TNF-alpha) has been shown to promote the apoptosis that is necessary for follicle assembly. The current study examines how TNF-alpha and progesterone interact to regulate primordial follicle assembly. ...


Displaying 15 of 15 results for "PGRMC2"