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Displaying 6 of 6 results for "PGRMC1"
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  1. Crystal structure of human PGRMC1 cytochrome b5-like domain PDB

    ID: PDB:4X8Y

    Description: Membrane-associated progesterone receptor component 1

  2. PGRC1_PONAB UniProt:Swiss-Prot

    ID: Q5RED0

    Description: Removed Membrane-associated progesterone receptor component 1 Lumenal Helical Cytoplasmic Cytochrome b5 heme-binding Phosphoserine Phosphoserine Phosp...

    gene.name: PGRMC1
  3. Transcription profiling of rat ovary in culture reveals interactions between progesterone and tumor necrosis factor-alpha in the regulation of primord... ArrayExpress

    ID: E-GEOD-8238

    Description: luded the surface membrane progesterone receptors PGRMC1, PGRMC2 and RDA288. The nuclear genomic P4 receptor was not expressed at appreciable levels. Progesterone increased the expression of several genes (TANK, NFkappaB, Bcl2l1 and Bcl2l2) involved in a signaling pathway that promotes cell survival and inhibits apoptosis. Observations indicate that P4 acts through the surface membrane progesterone receptors to regulate primordial follicle assembly, and that TNF-alpha can over-ride the inhibitory actions of P4 on follicle assembly. A major mechanism involved in the actions of P4 is an increase in cell survival genes and inhibition of the apoptosis pathway. Observations provide insight into the hormonal regulation of primordial follicle assembly and lead to novel approaches to potentially manipulate follicle assembly and reproductive capacity. Experiment Overall Design: RNA samples from two control groups (pooled untreated cultured ovaries) are compared to two treated groups (pooled cultured ovaries treated with progesterone)...

  4. PGRMC1 is a novel potential tumor biomarker of human renal cell carcinoma based on quantitative proteomics and integrative biological assessments ProteomeXchange

    ID: PXD004595

    Instrument: QSTAR

    Date Released: 01-29-2017

  5. Interactions Between Progesterone and Tumor Necrosis Factor-alpha in the Regulation of Primordial Follicle Assembly BioProject

    ID: PRJNA101175

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: luded the surface membrane progesterone receptors PGRMC1, PGRMC2 and RDA288. The nuclear genomic P4 receptor was not expressed at appreciable levels. Progesterone increased the expression of several genes (TANK, NFkappaB, Bcl2l1 and Bcl2l2) involved in a signaling pathway that promotes cell survival and inhibits apoptosis. Observations indicate that P4 acts through the surface membrane progesterone receptors to regulate primordial follicle assembly, and that TNF-alpha can over-ride the inhibitory actions of P4 on follicle assembly. A major mechanism involved in the actions of P4 is an increase in cell survival genes and inhibition of the apoptosis pathway. Observations provide insight into the hormonal regulation of primordial follicle assembly and lead to novel approaches to potentially manipulate follicle assembly and reproductive capacity. Keywords: expression analysis, progesterone, TNFa, follicle assembly, ovary Overall design: RNA samples from two control groups (pooled untreated cultured ovaries) are compared to two treated groups (pooled cultured ovaries treated with progesterone)...
  6. Transcription profiling of rat ovary in culture reveals interactions between progesterone and tumor necrosis factor-alpha in the regulation of primord... OmicsDI

    ID: E-GEOD-8238

    Date Released: 03-27-2012

    Description: luded the surface membrane progesterone receptors PGRMC1, PGRMC2 and RDA288. The nuclear genomic P4 receptor was not expressed at appreciable levels. Progesterone increased the expression of several genes (TANK, NFkappaB, Bcl2l1 and Bcl2l2) involved in a signaling pathway that promotes cell survival and inhibits apoptosis. Observations indicate that P4 acts through the surface membrane progesterone receptors to regulate primordial follicle assembly, and that TNF-alpha can over-ride the inhibitory actions of P4 on follicle assembly. A major mechanism involved in the actions of P4 is an increase in cell survival genes and inhibition of the apoptosis pathway. Observations provide insight into the hormonal regulation of primordial follicle assembly and lead to novel approaches to potentially manipulate follicle assembly and reproductive capacity. Experiment Overall Design: RNA samples from two control groups (pooled untreated cultured ovaries) are compared to two treated groups (pooled cultured ovaries treated with progesterone)...


Displaying 6 of 6 results for "PGRMC1"