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Displaying 20 of 177 results for "PEG10"
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  1. The placental gene PEG10 promotes progression of neuroendocrine prostate cancer [Expression] BioProject

    ID: PRJNA257216

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. The placental gene PEG10 promotes progression of neuroendocrine prostate cancer [aCGH] BioProject

    ID: PRJNA257215

    Keywords: Variation

    Access Type: download

  3. The placental gene PEG10 promotes progression of neuroendocrine prostate cancer [aCGH] ArrayExpress

    ID: E-GEOD-59985

    Description: nd identified up-regulation of the placental gene PEG10. We found that the androgen receptor and the E2F/RB pathway dynamically regulate distinct post-transcriptional and post-translational isoforms of PEG10 at different stages of NEPC development. In vitro, PEG10 promoted cell cycle progression from G0/G1 in the context of TP53 loss, and regulated Snail expression via TGF-β signaling to promote invasion. Finally we show in vivo proof of principal using an...

  4. The placental gene PEG10 promotes progression of neuroendocrine prostate cancer [Expression] OmicsDI

    ID: E-GEOD-59984

    Date Released: 01-10-2015

    Description: nd identified up-regulation of the placental gene PEG10. We found that the androgen receptor and the E2F/RB pathway dynamically regulate distinct post-transcriptional and post-translational isoforms of PEG10 at different stages of NEPC development. In vitro, PEG10 promoted cell cycle progression from G0/G1 in the context of TP53 loss, and regulated Snail expression via TGF-β signaling to promote invasion. Finally we show in vivo proof of principal using an...

  5. The placental gene PEG10 promotes progression of neuroendocrine prostate cancer [aCGH] OmicsDI

    ID: E-GEOD-59985

    Date Released: 01-10-2015

    Description: nd identified up-regulation of the placental gene PEG10. We found that the androgen receptor and the E2F/RB pathway dynamically regulate distinct post-transcriptional and post-translational isoforms of PEG10 at different stages of NEPC development. In vitro, PEG10 promoted cell cycle progression from G0/G1 in the context of TP53 loss, and regulated Snail expression via TGF-β signaling to promote invasion. Finally we show in vivo proof of principal using an...

  6. The placental gene PEG10 promotes progression of neuroendocrine prostate cancer ArrayExpress

    ID: E-GEOD-59986

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  7. PEG3_PANPA UniProt:Swiss-Prot

    ID: A1YGK6

    Description: Paternally-expressed gene 3 protein SCAN box 2-1 2-2 2-3 1-1

  8. PEG3_GORGO UniProt:Swiss-Prot

    ID: A1YFC1

    Description: Paternally-expressed gene 3 protein SCAN box 2-1 2-2 2-3 1-1

  9. Methanosarcina horonobensis HB-1 = JCM 15518 : Methanogenic archaea and the global carbon cycle BioProject

    ID: PRJNA230942

    Keywords: Genome sequencing

    Access Type: download

  10. Role of Tet1 in genomic imprinting erasure [RRBS-PGC] BioProject

    ID: PRJNA214851

    Keywords: Epigenomics

    Access Type: download

    dataset.description: by the dysregulation of imprinted genes, such as Peg10 and Peg3, which exhibit aberrant hypermethylation in the paternal allele of differential methylated regions (DMRs). RNA-seq reveals extensive dysregulation of imprinted genes in the next generation due to paternal functional loss of Tet1. Genome-wide DNA methylation analysis of E13.5 PGCs and sperm derived from Tet1-KO mice reveals hypermethylation of DMRs of imprinted genes in sperm, which can be traced back to PGCs. Dynamics of methylation change in Tet1-affected sites suggested that Tet1 swipes remaining methylation including imprinted genes at late reprogramming stage. We also revealed that Tet1play a role in paternal imprinting erasure in females germline. Thus, our study establishes a critical function for Tet1 in the erasure of genomic imprinting. Overall design: Genome-wide DNA methylation analysis of E13.5 PGCs from control and Tet1-KO mice...
  11. Role of Tet1 in genomic imprinting erasure [RNA-seq] ArrayExpress

    ID: E-GEOD-49761

    Description: by the dysregulation of imprinted genes, such as Peg10 and Peg3, which exhibit aberrant hypermethylation in the paternal allele of differential methylated regions (DMRs). RNA-seq reveals extensive dysregulation of imprinted genes in the next generation due to paternal functional loss of Tet1. Genome-wide DNA methylation analysis of E13.5 PGCs and sperm derived from Tet1-KO mice reveals hypermethylation of DMRs of imprinted genes in sperm, which can be traced back to PGCs. Dynamics of methylation change in Tet1-affected sites suggested that Tet1 swipes remaining methylation including imprinted genes at late reprogramming stage. We also revealed that Tet1play a role in paternal imprinting erasure in females germline. Thus, our study establishes a critical function for Tet1 in the erasure of genomic imprinting. Gene expression analysis of E9.5 embryos...

  12. RNA-Sequencing Identifies Novel Imprinted Genes in Human Placenta (SNP genotyping) ArrayExpress

    ID: E-GEOD-56685

    Description: ) and confirmed five known imprinted genes (AIM1, PEG10, RHOBTB3, ZFAT and ZFAT-AS1). The main functions of the proteins encoded by the imprinted genes can be grouped as being involved in: i) cellular apoptosis and tissue development; ii) regulating inflammation and modulating the immune system; iii) facilitating metabolic processes and iv) regulating the cell cycle. Ten family trios (mother, father, child) were analysed using SNP genotyping. Raw data contains additional two samples that were not used....

  13. The Minnesota Poll: March, 1990 - Wave 2 Dataverse

    Description: llowing issues and topics: Situation in Minnesota(1); household financial situation(1); minorities (15); racial integration(5); race relations(12)....

    Person: The Star Tribune

    Release Date: 08-26-2007

  14. ChIP-chip studies of Drosophila melanogaster transcription factors HB and MED OmicsDI

    ID: E-TABM-1021

    Date Released: 05-02-2014

    Description: embryos, and affinity purified antibodies against HB and MED. Affinity purification of the antibodies was performed with E.coli expressed His-tag fusions of the N-terminal portion of the full length protein (designated as 1, e.g....

  15. HEADBOBBER__A_COMBINED_MORPHOGENETIC_AND_COCHLEOSACCULAR_MOUSE_MODEL_TO_STUDY_10qter_DELETIONS_IN_HUMAN_DEAFNESS BioProject

    ID: PRJEB2732

    Keywords: Other

    Access Type: download

    dataset.description: The recessive mouse mutant headbobber (hb) displays the characteristic behavioural traits associated with vestibular defects including headbobbing, circling and deafness....
  16. Using RNA sequencing for identifying gene imprinting and random monoallelic expression in human placenta (SNP genotyping) BioProject

    ID: PRJNA244577

    Keywords: Variation

    Access Type: download

    dataset.description: eritance and estimating the abundance of parental expressed alleles. Imprinted genes showed consistent expression from either parental allele, as demonstrated by the SNP content of sequenced transcripts, while monoallelically expressed genes had random activity of parental alleles. We revealed 4 novel possible imprinted genes (LGALS8, LGALS14, PAPPA2 and SPTLC3) and confirmed the imprinting of 4 genes (AIM1, PEG10, RHOBTB3 and ZFAT-AS1) in human placenta. The major finding was the identification of 4 genes (ABP1, BCLAF1, IFI30 and ZFAT) with random allelic bias, expressing one of the parental alleles preferentially. The main functions of the imprinted and monoallelically expressed genes included: i) mediating cellular apoptosis and tissue development; ii) regulating inflammation and immune system; iii) facilitating metabolic processes; and iv) regulating cell cycle. Overall design: Ten family trios (mother, father, child) were analysed using SNP genotyping. Raw data ...
  17. Transcription profiling by array of Nurr1 gene expression in human neural stem cell lines OmicsDI

    ID: E-GEOD-58475

    Date Released: 04-30-2015

    Description: ion of genes modulated by Nurr1 overexpression in HB-1 HB-1 cells overexpressing Nurr1...

  18. Transcription profiling of human vascular smooth muscle cells treated with glucose oxidase and human haemoglogib reveals ferrous hemoglobin can protec... ArrayExpress

    ID: E-MEXP-2263

    Description: Hemoglobin (Hb) is released from red blood cells (RBC) during intravascular hemolysis. Cell free Hb has been implicated to p...

  19. Using RNA sequencing for identifying gene imprinting and random monoallelic expression in human placenta (RNA-seq) BioProject

    ID: PRJNA243888

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: eritance and estimating the abundance of parental expressed alleles. Imprinted genes showed consistent expression from either parental allele, as demonstrated by the SNP content of sequenced transcripts, while monoallelically expressed genes had random activity of parental alleles. We revealed 4 novel possible imprinted genes (LGALS8, LGALS14, PAPPA2 and SPTLC3) and confirmed the imprinting of 4 genes (AIM1, PEG10, RHOBTB3 and ZFAT-AS1) in human placenta. The major finding was the identification of 4 genes (ABP1, BCLAF1, IFI30 and ZFAT) with random allelic bias, expressing one of the parental alleles preferentially. The main functions of the imprinted and monoallelically expressed genes included: i) mediating cellular apoptosis and tissue development; ii) regulating inflammation and immune system; iii) facilitating metabolic processes; and iv) regulating cell cycle. Overall design: Placentas from ten family trios were analysed using RNA-Seq....
  20. AY STRUCTURE DETERMINATION OF BOVINE CARBONMONOXY HB AT 2.1 A RESOLUTION AND ITS RELATIONSHIP TO THE QUATERNARY STRUCTURE OF OTHER HB CRYSTAL FORMS... PDB

    ID: PDB:1FSX

    Description: CARBONMONOXY HB


Displaying 20 of 177 results for "PEG10"