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Displaying 20 of 70 results for "PCDH8"
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  1. STRUCTURE OF THE P PILUS USHER (PAPC) TRANSLOCATION PORE PDB

    ID: PDB:2VQI

    Description: OUTER MEMBRANE USHER PROTEIN PAPC

  2. Hydrogen modulates signal transduction through manipulating oxidized phospholipid mediators ArrayExpress

    ID: E-GEOD-62434

    Description: asured at 4 hours after exposure to phospholipid, PAPC or oxidized PAPC that had been air-oxidized for 3 days with 0, 1.3 or 5% H2. Three independent experiments were performed for each experiment....

  3. Transcription profiling of UV- or oxidized lipid treated dermal skin fibroblasts ArrayExpress

    ID: E-GEOD-13606

    Description: yl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (PAPC), which then induced the synthesis of the stress response protein heme oxygenase 1 (HO-1) in dermal fibroblasts. Here we examined the effects of UVA-1 and (UV-) oxidized phospholipids on the global gene expression in human dermal fibroblasts. We identified a cluster of genes that were co-induced by UVA-1-oxidized PAPC and UVA-1 radiation. The cluster included HO-1, glutamate-cysteine ligase modifier subunit (GCLM), aldo-keto reductases-1-C1 and -C2 (AKR1C1,...

  4. Hydrogen modulates signal transduction through manipulating oxidized phospholipid mediators BioProject

    ID: PRJNA264091

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: asured at 4 hours after exposure to phospholipid, PAPC or oxidized PAPC that had been air-oxidized for 3 days with 0, 1.3 or 5% H2. Three independent experiments were performed for each experiment....
  5. Evidence for the importance of OxPAPC interaction with cysteines in regulating endothelial cell function ArrayExpress

    ID: E-GEOD-35709

    Description: 2-arachidonoyl-sn-glycerol-2-phosphatidylcholine (PAPC), referred to as OxPAPC, accumulate in atherosclerotic lesions and regulate over 1000 genes in human aortic endothelial cells (HAEC). We previously demonstrate...

  6. Crystal structure of the C-terminal domain of the PapC usher PDB

    ID: PDB:3L48

    Description: Outer membrane usher protein PapC

  7. Crystal structure of Usher PapC translocation pore PDB

    ID: PDB:3FIP

    Description: Outer membrane usher protein papC

  8. Structural homology between the C-terminal domain of the PapC usher and its plug PDB

    ID: PDB:2KT6

    Description: Outer membrane usher protein papC

  9. Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids ArrayExpress

    ID: E-GEOD-29903

    Description: Cs) to produce inflammatory cytokines, such as IL-8. In studies with mouse models, we previously demonstrated that genetic variation in inflammatory responses of endothelial cells to oxidized lipids contributes importantly to atherosclerosis susceptibility. We now show that s...

  10. PCDB8_PANTR UniProt:Swiss-Prot

    ID: Q5DRC6

    Description: Protocadherin beta-8 Extracellular Helical Cytoplasmic Cadherin 1 Cadherin 2 Cadherin 3 Cadherin 4 Cadherin 5 Ca...

  11. PCDA8_PANTR UniProt:Swiss-Prot

    ID: Q5DRE4

    Description: Protocadherin alpha-8 Extracellular Helical Cytoplasmic Cadherin 1 Cadherin 2 Cadherin 3 Cadherin 4 Cadherin 5 C...

  12. UV- or oxidized lipid treated dermal skin fibroblasts BioProject

    ID: PRJNA110627

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: yl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (PAPC), which then induced the synthesis of the stress response protein heme oxygenase 1 (HO-1) in dermal fibroblasts. Here we examined the effects of UVA-1 and (UV-) oxidized phospholipids on the global gene expression in human dermal fibroblasts. We identified a cluster of genes that were co-induced by UVA-1-oxidized PAPC and UVA-1 radiation. The cluster included HO-1, glutamate-cysteine ligase modifier subunit (GCLM), aldo-keto reductases-1-C1 and -C2 (AKR1C1,...
  13. Genome-wide DNA Methylation Analysis Reveals Novel Targets for Drug Development in Mantle Cell Lymphoma ArrayExpress

    ID: E-GEOD-19243

    Description: ntified four hypermethylated genes CDKN2B, MLF-1, PCDH8, HOXD8 and four hypomethylated genes CD37, HDAC1, NOTCH1 and CDK5 where aberrant methylation was associated with inverse changes in mRNA levels. MassArray Epityper analysis confirmed the presence of differential methylation at the promoter region of these genes. Immunohistochemical analysis of an independent cohort of 14 MCL patient samples, confirmed CD37 surface expression in 93% of patients, validating its selection as a target for MCL therapy. Treatment of MCL cell lines with a novel small modular immunopharmaceutical(CD37-SMIP) resulted in sign...

  14. A mesodermal gene regulatory network directed by zebrafish No tail ArrayExpress

    ID: E-GEOD-12331

    Description: er studies (wnt11, flh, vent, msgn1, myod, fgf8, pcdh8) and these probes are arrayed on both slides slide. We also included in this design 502 intensity control probes. Finally there are 2,256 controls added by Agilent. The final design contained 378,002 probes, including 365,537 experimental probes divided between nine microarray slides: slides 1-8 contained 40,616 experimental probes and slide 9 contained 40, 609. Further information on design and manufacture of the microarrays can be found on the Agilent Technologies website (www.agilent.com)....

  15. A network of transcriptional repression specifies muscle fibre type in the zebrafish embryo ArrayExpress

    ID: E-GEOD-10883

    Description: ylz2, myhz2, wnt11, flh, vent, msgn1, myod, fgf8, pcdh8) and these probes are arrayed on both slides slide. Finally on each array there are 1804 controls added by Agilent. The final design contained 352,490 probes divided between two microarray slides. Further information on design and manufacture of the microarrays can be found at the Agilent Technologies website....

  16. Genome-wide DNA Methylation Analysis Reveals Novel Targets for Drug Development in Mantle Cell Lymphoma OmicsDI

    ID: E-GEOD-19243

    Date Released: 05-01-2014

    Description: ntified four hypermethylated genes CDKN2B, MLF-1, PCDH8, HOXD8 and four hypomethylated genes CD37, HDAC1, NOTCH1 and CDK5 where aberrant methylation was associated with inverse changes in mRNA levels. MassArray Epityper analysis confirmed the presence of differential methylation at the promoter region of these genes. Immunohistochemical analysis of an independent cohort of 14 MCL patient samples, confirmed CD37 surface expression in 93% of patients, validating its selection as a target for MCL therapy. Treatment of MCL cell lines with a novel small modular immunopharmaceutical(CD37-SMIP) resulted in sign...

  17. Evidence for the importance of OxPAPC interaction with cysteines in regulating endothelial cell function BioProject

    ID: PRJNA152049

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: 2-arachidonoyl-sn-glycerol-2-phosphatidylcholine (PAPC), referred to as OxPAPC, accumulate in atherosclerotic lesions and regulate over 1000 genes in human aortic endothelial cells (HAEC). We previously demonstrate...
  18. Transcription profiling of UV- or oxidized lipid treated dermal skin fibroblasts OmicsDI

    ID: E-GEOD-13606

    Date Released: 05-01-2014

    Description: yl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (PAPC), which then induced the synthesis of the stress response protein heme oxygenase 1 (HO-1) in dermal fibroblasts. Here we examined the effects of UVA-1 and (UV-) oxidized phospholipids on the global gene expression in human dermal fibroblasts. We identified a cluster of genes that were co-induced by UVA-1-oxidized PAPC and UVA-1 radiation. The cluster included HO-1, glutamate-cysteine ligase modifier subunit (GCLM), aldo-keto reductases-1-C1 and -C2 (AKR1C1,...

  19. PCDL_ACRMI UniProt:Swiss-Prot

    ID: B8V7Q1

    Description: Protocadherin-like protein Extracellular Helical Cytoplasmic Cadherin 1 Cadherin 2 Cadherin 3 Cadherin 4 Cadherin 5 Cadherin 6 Cadh...

  20. Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids BioProject

    ID: PRJNA140811

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Cs) to produce inflammatory cytokines, such as IL-8. In studies with mouse models, we previously demonstrated that genetic variation in inflammatory responses of endothelial cells to oxidized lipids contributes importantly to atherosclerosis susceptibility. We now show that s...

Displaying 20 of 70 results for "PCDH8"