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Displaying 20 of 26 results for "PCDH10"
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  1. Genome-wide profiling of EZH2-interacting RNAs reveals lncRNA MALAT1 inhibiting PCDH10 by recruiting PRC2 in metastatic gastric cancer cells BioProject

    ID: PRJEB10143

    Keywords: Other

    Access Type: download

  2. Genome-wide profiling of EZH2-interacting RNAs reveals lncRNA MALAT1 inhibiting PCDH10 by recruiting PRC2 in metastatic gastric cancer cells OmicsDI

    ID: E-MTAB-3767

    Date Released: 02-23-2016

    Description: hat EZH2-associated lncRNA MALAT1 tethers EZH2 to PCDH10 promoter for its transcriptional repression and contributes to gastric cellular invasion and migration....

  3. Genome-wide profiling of EZH2-interacting RNAs reveals lncRNA MALAT1 inhibiting PCDH10 by recruiting PRC2 in metastatic gastric cancer cells ArrayExpress

    ID: E-MTAB-3767

    Description: hat EZH2-associated lncRNA MALAT1 tethers EZH2 to PCDH10 promoter for its transcriptional repression and contributes to gastric cellular invasion and migration....

  4. Crystal Structure of Mouse Protocadherin-15 EC9-10 PDB

    ID: PDB:5KJ4

    Description: protocadherin15-EC8-10

  5. Crystal Structure of Human Protocadherin-15 EC8-10 PDB

    ID: PDB:4XHZ

    Description: protocadherin15-EC8-10

  6. EpCAM knock-down in FaDu head and neck carcinoma cells ArrayExpress

    ID: E-GEOD-37257

    Description: ., 2004). Equal amounts of total RNA (RIN score = 10) from control- and EpCAM-siRNA-treated FaDu cells were next subjected to a single, explorative cDNA microarray analysis with the aim to identify potential target genes of the signal transduction cascade of EpCAM. All genes, which were up- or down-regulated by at least two-fold (>2-fold; 716 genes up-regulated, 552 genes down-regulated), were then subjected to a Panther classification software analysis (). Special emphasis was put on the regulation of genes associated with signalling pathways. Angiogenesis, Alzheimer's disease-presenilin pathway, Wnt signalling pathway, inflammation and cadherin signalling pathways were most strongly affected by EpCAM knock-down. mRNA levels of selected genes differently regulated following partial knock-down of EpCAM included the co-regulated genes for secreted frizzled-related protein 5, protocadherin 10, dickkopf homolog 2, MMP24, SPARC, Myst3, ErbB4, MMP12, WISP2, MMP7, Nanos1, WNT9A, and the counter-regulated genes for MMP11, fibronectin 1, DACT3, WNT2B, WNT5A, APC2, Spondin 1, and cateninα2. All genes except for protocadherin 10, Myst3, ErbB4, and WNT2B were validated in RT-PCR assays. Since several matrix metalloproteases were regulated after EpCAM knock-down and EpCAM is known to correlate with invasion, we chose this protein family for in-depth analysis. Matrix metalloprotease 7 (MMP-7) is a soluble factor, which, unlike other family members, is preferentially expressed in epithelial cells (Wilson, et al., 1995). Since EpCAM also displays highest expression in epithelia, we chose to proceed with the analysis of MMP7. SiRNA-mediated knock-down of EpCAM resulted in a comparable 50% down-regulation of MMP7 mRNA levels in RT-PCR and qPCR. C...

  7. PCDAA_PANTR UniProt:Swiss-Prot

    ID: Q5DRF4

    Description: Protocadherin alpha-10 Extracellular Helical Cytoplasmic Cadherin 1 Cadherin 2 Cadherin 3 Cadherin 4 Cadherin 5 ...

  8. PCDAA_MOUSE UniProt:Swiss-Prot

    ID: Q91Y20

    Description: Protocadherin alpha-10 Extracellular Helical Cytoplasmic Cadherin 1 Cadherin 2 Cadherin 3 Cadherin 4 Cadherin 5 ...

  9. PCDBA_PANTR UniProt:Swiss-Prot

    ID: Q5DRD9

    Description: Protocadherin beta-10 Extracellular Helical Cytoplasmic Cadherin 1 Cadherin 2 Cadherin 3 Cadherin 4 Cadherin 5 C...

  10. PCDL_ACRMI UniProt:Swiss-Prot

    ID: B8V7Q1

    Description: Protocadherin-like protein Extracellular Helical Cytoplasmic Cadherin 1 Cadherin 2 Cadherin 3 Cadherin 4 Cadherin 5 Cadherin 6 Cadh...

  11. EpCAM knock-down in FaDu head and neck carcinoma cells BioProject

    ID: PRJNA159229

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ., 2004). Equal amounts of total RNA (RIN score = 10) from control- and EpCAM-siRNA-treated FaDu cells were next subjected to a single, explorative cDNA microarray analysis with the aim to identify potential target genes of the signal transduction cascade of EpCAM. All genes, which were up- or down-regulated by at least two-fold (>2-fold; 716 genes up-regulated, 552 genes down-regulated), were then subjected to a Panther classification software analysis (http://www.pantherdb.org/). Special emphasis was put on the regulation of genes associated with signalling pathways. Angiogenesis, Alzheimer's disease-presenilin pathway, Wnt signalling pathway, inflammation and cadherin signalling pathways were most strongly affected by EpCAM knock-down. mRNA levels of selected genes differently regulated following partial knock-down of EpCAM included the co-regulated genes for secreted frizzled-related protein 5, protocadherin 10, dickkopf homolog 2, MMP24, SPARC, Myst3, ErbB4, MMP12, WISP2, MMP7, Nanos1, WNT9A, and the counter-regulated genes for MMP11, fibronectin 1, DACT3, WNT2B, WNT5A, APC2, Spondin 1, and cateninα2. All genes except for protocadherin 10, Myst3, ErbB4, and WNT2B were validated in RT-PCR assays. Since several matrix metalloproteases were regulated after EpCAM knock-down and EpCAM is known to correlate with invasion, we chose this protein family for in-depth analysis. Matrix metalloprotease 7 (MMP-7) is a soluble factor, which, unlike other family members, is preferentially expressed in epithelial cells (Wilson, et al., 1995). Since EpCAM also displays highest expression in epithelia, we chose to proceed with the analysis of MMP7. SiRNA-mediated knock-down of EpCAM resulted in a comparable 50% down-regulation of MMP7 mRNA lev...
  12. PCD16_MOUSE UniProt:Swiss-Prot

    ID: E9PVD3

    Description: Protocadherin-16 Extracellular Helical Cytoplasmic Cadherin 1 Cadherin 2 Cadherin 3 Cadherin 4 Cadherin 5 Cadherin 6 Cadherin 7 Cad...

  13. FAT1_HUMAN UniProt:Swiss-Prot

    ID: Q14517

    Description: Protocadherin Fat 1 Protocadherin Fat 1, nuclear form Extracellular Helical Cytoplasmic Cadherin 1 Cadherin 2 Ca...

  14. Additional file 6: Figure S4. of Whole-genome bisulfite sequencing of cell-free DNA identifies signature associated with metastatic breast cancer Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3637367_D4

    Release Date: 12-15-2016

    Description: ing results shown by gene for GP5 (A), HTR1B (B), PCDH10 (C), and UNC13A (D). The top panel, separated by a thick black line, shows a histogram representing the percent methylation value for each CpG locus in each amplicon for H, DFS, and MBC. I...

  15. FAT2_RAT UniProt:Swiss-Prot

    ID: O88277

    Description: Protocadherin Fat 2 Extracellular Helical Cytoplasmic Cadherin 1 Cadherin 2 Cadherin 3 Cadherin 4 Cadherin 5 Cadherin 6 Cadherin 7 ...

  16. FAT3_RAT UniProt:Swiss-Prot

    ID: Q8R508

    Description: Protocadherin Fat 3 Extracellular Helical Cytoplasmic Cadherin 1 Cadherin 2 Cadherin 3 Cadherin 4 Cadherin 5 Cadherin 6 Cadherin 7 ...

  17. EpCAM knock-down in FaDu head and neck carcinoma cells OmicsDI

    ID: E-GEOD-37257

    Date Released: 04-23-2012

    Description: ., 2004). Equal amounts of total RNA (RIN score = 10) from control- and EpCAM-siRNA-treated FaDu cells were next subjected to a single, explorative cDNA microarray analysis with the aim to identify potential target genes of the signal transduction cascade of EpCAM. All genes, which were up- or down-regulated by at least two-fold (>2-fold; 716 genes up-regulated, 552 genes down-regulated), were then subjected to a Panther classification software analysis (http://www.pantherdb.org/). Special emphasis was put on the regulation of genes associated with signalling pathways. Angiogenesis, Alzheimer's disease-presenilin pathway, Wnt signalling pathway, inflammation and cadherin signalling pathways were most strongly affected by EpCAM knock-down. mRNA levels of selected genes differently regulated following partial knock-down of EpCAM included the co-regulated genes for secreted frizzled-related protein 5, protocadherin 10, dickkopf homolog 2, MMP24, SPARC, Myst3, ErbB4, MMP12, WISP2, MMP7, Nanos1, WNT9A, and the counter-regulated genes for MMP11, fibronectin 1, DACT3, WNT2B, WNT5A, APC2, Spondin 1, and cateninα2. All genes except for protocadherin 10, Myst3, ErbB4, and WNT2B were validated in RT-PCR assays. Since several matrix metalloproteases were regulated after EpCAM knock-down and EpCAM is known to correlate with invasion, we chose this protein family for in-depth analysis. Matrix metalloprotease 7 (MMP-7) is a soluble factor, which, unlike other family members, is preferentially expressed in epithelial cells (Wilson, et al., 1995). Since EpCAM also displays highest expression in epithelia, we chose to proceed with the analysis of MMP7. SiRNA-mediated knock-down of EpCAM resulted in a comparable 50% down-regulation of MMP7 mRNA lev...

  18. Expression data from CD8+ Central memory T cells after different time periods of Concanavalin A in vitro activation. OmicsDI

    ID: E-GEOD-34618

    Date Released: 05-11-2012

    Description: l interacting partner for p56lck in nonlytic TIL, Protocadherin-18 (‘pcdh18’), and show that pcdh18 is transcribed upon in vitro or in vivo activation of CD8+ central memory T cells (CD44+CD62LhiCD127+) coincident with conversion into effector memory cells (CD44+CD62LloCD127+). Expression of pcdh18 in primary CD8+ effector cells induces the phenotype of nonlytic...

  19. X-Ray Diffraction data from human WAVE Regulatory Complex (WRC) bound to a WIRS peptide from Protocadherin-10, source of 4N78 structure SBGrid

    ID: doi:10.15785/SBGRID/132

    Release Date: 11-02-2016

  20. Expression data from CD8+ Central memory T cells after different time periods of Concanavalin A in vitro activation ArrayExpress

    ID: E-GEOD-34618

    Description: l interacting partner for p56lck in nonlytic TIL, Protocadherin-18 (‘pcdh18’), and show that pcdh18 is transcribed upon in vitro or in vivo activation of CD8+ central memory T cells (CD44+CD62LhiCD127+) coincident with conversion into effector memory cells (CD44+CD62LloCD127+). Expression of pcdh18 in primary CD8+ effector cells induces the phenotype of nonlytic...


Displaying 20 of 26 results for "PCDH10"