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Displaying 20 of 24 results for "PAX2"
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  1. Down-regulation of PAX2 affects ovarian cancer cell growth and migration BioProject

    ID: PRJNA143339

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Pax2 Dependent Expression in the Intermediate Mesoderm at E11.5 BioProject

    ID: PRJNA270228

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Pax2 Dependent Expression in the Intermediate Mesoderm at E11.5 ArrayExpress

    ID: E-GEOD-64129

    Description: Heterozygous and homozygous Pax2 E11.5 embryos were collected and the intermediate mesoderm was dissected and dispersed into single cells. The Pax2

  4. Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Dnase-Seq] ArrayExpress

    ID: E-GEOD-59782

    Description: in the HEE open chromatin, include the motif for paired box 2 (PAX2). PAX2 is a critical transcriptional regulator of urogenital tract development, which is well studied in the kidney but is unexplored in the epididymis. Due to the limited lifespan of primary HEE cells in culture we investigated the role of PAX2 in an immortalized HEE cell line (REP). First, REP cells were evaluated by DNase-seq and their open chromatin map overlapped that of primary HEE cells at ~ 65% of sites. Moreover, the PAX2-binding motif was again identified as an overrepresented TFBS within intergenic open chromatin, though on fewer chromosomes than in the primary HEE cells. To i...

  5. Expression analysis of Human esophagus cancer cell line TE-1 transfected with PCDNA3.1 and PCDNA3.1-Pax2 ArrayExpress

    ID: E-GEOD-64093

    Description: level changes of TE-1 transfected with PCDNA3.1-Pax2 ,compared to TE-1 transfected with PCDNA3.1. Compare PAX2 activated genes by analyzing mRNA profilings between pcDNA3.1 and pcDNA3.1-PAX2

  6. PAX2-null progenitors define multiple lineages with common expression signatures in benign and neoplastic oviductal epithelium ArrayExpress

    ID: E-GEOD-58842

    Description: ed with older age and serous cancer. We evaluated PAX2 expression in proliferating oviductal cells, normal mucosa, SCOUTs, Walthard cell nests, STINs and HGSCs. Non-ciliated cells in normal mucosa were PAX2 positive but became PAX2 negative in multilayered epithelium. PAX2 ...

  7. Actions of tamoxifen in the uterus and its molecular effectors in endometrial carcinogenesis. BioProject

    ID: PRJNA93193

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: oxifen. Among those target genes, we identified a paired-box gene PAX2 that is critically involved in cell proliferation and carcinogenesis in the endometrium. Our experiments also demonstrated that PAX2 is activated by oestrogen and tamoxifen in endometrial carcinomas but not in normal endometrium, and this activation is associated with cancer-linked hypomethylation of the PAX2 promoter. Keywords: actions of tamoxifen Overall design: each experiment repeat 2 times....
  8. Comparison of gene expression between wild-type and PTIP deficient chicken DT40 B cells BioProject

    ID: PRJNA121245

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: PTIP (Pax2 transactivation domain-interacting protein) is a nuclear protein containing six BRCT domains. It has been shown that PTIP affe...
  9. Gene expression profiling in sinonasal sarcoma ArrayExpress

    ID: E-GEOD-52252

    Description: ors including 8 SNS (6 with PAX3-MAML3 fusion and 2 with PAX3 rearrangement only) and 33 cases from other 10 different types of tumors. Gene expression profiling of fusion group including 8 SNA vs.non-fusion group including 33 control tumors were analyszed....

  10. Expression data of lungs from chickens infected with different H5N1 Avian Influenza Viruses [24 hours post infection] ArrayExpress

    ID: E-GEOD-53931

    Description: Samples were named as follows: CK10 (CK10-1,CK10-2,CK10-3), CK-PAX3 (CK-PAX3-1,CK-PAX3-2, CK-PAX3-3), Control (C-1, C-2, C-3)....

  11. PAX5 overexpression is not enough to reestablish the mature B-cell phenotype in classical Hodgkin lymphoma ArrayExpress

    ID: E-GEOD-44244

    Description: used and secured by complex molecular mechanisms. 2 Burkitt lymphoma cell lines (Raji, Namalwa), the Hodgkin lymphoma cell line L428 and the PAX5-producing L428 (L428-PAX5) with or without 5-aza-2′-deoxycytidine/Trichostatin A treatment were analysed in triplicate....

  12. Expression data of lungs from chickens infected with different H5N1 Avian Influenza Viruses [12 hours post infection] BioProject

    ID: PRJNA233995

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Samples were named as follows: CK10 (CK10-1,CK10-2,CK10-3), CK-PAX3 (CK-PAX3-1,CK-PAX3-2, CK-PAX3-3), Control (C-1, C-2, C-3)....
  13. Transcription profiling of human neuroblastoma cell line expressing PHOX2B ArrayExpress

    ID: E-GEOD-9339

    Description: ments of two independent clones (K2 and K5), with 2 or 4 time points, respectively....

  14. The role of the Janus-faced transcription factor PAX5-JAK2 in acute lymphoblastic leukemia BioProject

    ID: PRJNA243350

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: 5-JAK2 chimera, which consists of the DNA-binding paired domain of PAX5 and the active kinase domain of JAK2, is a nuclear protein that has the ability to bind to wild-type PAX5 target loci. Moreover, our data provide compelling evidence that PAX5-JAK2 functions as nuclear catalytically active kinase that autophosphorylates and in turn phosphorylates and activates downstream STATs in an apparently non-canonical mode. The chime...
  15. A genome-wide analysis of open chromatin in human epididymis epithelial cells reveals novel candidate regulatory elements for male infertility [DNase-... BioProject

    ID: PRJNA219502

    Keywords: Epigenomics

    Access Type: download

    dataset.description: s including ELF5 and ELF3, the androgen receptor, Pax2 and Sox9, as components of epididymis transcriptional networks. Active genes, which are targets of each transcription factor, reveal important biological processes in the epididymis epithelium. Overall design: To identify cis-regulatory elements for genes expressed in human epididymis epithelial cells we generated genome-wide maps of open chromatin by DNase-seq....
  16. Analysis of the MSX1 downstream signaling network in neuroblastoma BioProject

    ID: PRJNA103023

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ments of two independent clones (K2 and K5), with 2 or 4 time points, respectively....
  17. FJ001: Retinoic acid-dependent and -independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons ArrayExpress

    ID: E-GEOD-32940

    Description: ions of the orphan nuclear receptor Nurr1 and the paired-like homeobox transcription factor Pitx3. Whereas all mdDA neurons require Nurr1 for expression of Th and survival, dependence on Pitx3 is only displayed by the mdDA subpopulation that will form the substan...

  18. Transcription profiling of human monoclonal B-cell PTLD, collected from 20 solid organ transplant recipients ArrayExpress

    ID: E-GEOD-8123

    Description: Post-transplant lymphoproliferative disorders (PTLD) are a major complication of solid organ transplantation and represent a cause of severe morbidity...

  19. Extinction learning BioProject

    ID: PRJNA146217

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: peatedly presented in the absence of a previously paired aversive event. Extinction of fear memories has been implicated with the treatment of anxiety disease but the molecular processes that underlie fear extinctionare only beginning to emerge. Here we show that fear extinction initiates up-regulation of hippocampal insulin-growth factor 2 (Igf2) and down-regulation of insulin-growth factor...
  20. Comparative Transcriptional Analysis of Canine and Human Diffuse Large B cell Lymphoma (DLBCL). Molecular Signatures of NF-κB Pathway Activation and ... ArrayExpress

    ID: E-GEOD-30881

    Description: LBCL and 10 healthy) in total. However, data from 2 canine DLBCL samples did not meet our required quality and were removed from further analysis. Only data from 33 (23 DLBCL and 10 healthy) samples were used for analysis. The generated data were used for differential expression analysis, co-expression analysis and pathway analysis, and compared with analysis of publicly available microarray data (GSE12195) from human healthy and DLBCL lymph nodes. The comparisons between species at gene level were performed by mapping the probesets in canine microarrays to orthologous genes in humans and vice versa....


Displaying 20 of 24 results for "PAX2"