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Displaying 20 of 29 results for "OCA2"
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  1. Data from: Albinism in phylogenetically and geographically distinct populations of Astyanax cavefish arises through the same loss-of-function ... Dryad

    DateIssued: 07-18-2013

    Description: ed from the Micos cave locality in 1970, in which albinism appeared over the last two decades. We combined novel coloration analyses, coding sequence comparisons, and mRNA expression level studies to investigate the origin of albinism in captive-bred Micos cavefish. We discovered albino Micos cavefish harbor two copies of a loss-of-function Oca2 allele previously identified in the geographically distant Pachón cave population. This result suggests that phylogenetically young Micos cavefish and phylogenetically old Pachón fish inherited this

  2. OCA2_SCHPO UniProt:Swiss-Prot

    ID: O59763

    Description: Serine/threonine-protein kinase oca2 Protein kinase ATP His-rich Proton acceptor ATP Phosphoserine Phosphoseri...

  3. Raw Quantitative PCR Measurements Dryad

    DateIssued: 06-07-2013

    Description: ta collected for quantitative PCR measurements of Oca2 (experimental gene) expression and GAPDH (control gene) expression. These data were collected using a Bio-Rad MiniOpticon real-time PCR instrument....

  4. Data from: Evolutionary history inferred from the de novo assembly of a non-model organism, the blue-eyed black lemur Dryad

    DateIssued: 08-27-2015

    Description: ion in humans, where 5′ regulatory variation of OCA2 explains most of the brown/blue eye colour differences. We built a de novo genome assembly for E. flavifrons, providing the most complete lemur genome to date, and a high confidence consensus sequence for close sister species E. macaco, the (brown-eyed) black lemur. From diversity and divergence patterns across the genomes, we estimated a recent split time of the two species (160 Kya) and temporal fluctuations in effective population sizes that accord with known environmental changes. By looking for regions of unusually low diversity, we identified potential signals of directional selection in E. flavifrons at MITF, a melanocyte development gene that regul...

  5. Descriptive Statistics Coloration Measurements Dryad

    DateIssued: 06-07-2013

    Description: This data file contains the descriptive statistics for all raw coloration and greyscale measurements collected from each of seven individuals from fiv...

    dataset.keywords: ocular and cutaneous albinism type II (Oca2); melanin; regressive phenotypic evolution; epigean; hypogean; mitocho...
  6. Raw filter Images Dryad

    DateIssued: 06-07-2013

    Description: This folder contains raw, high-resolution filter images from which coloration measurements were collected.

    dataset.keywords: ocular and cutaneous albinism type II (Oca2); melanin; regressive phenotypic evolution; epigean; hypogean; mitocho...
  7. Raw fin clip Photographs Dryad

    DateIssued: 06-07-2013

    Description: These are the raw images of caudal fin clips collected from a representative albino Micos cavefish and a representative pigmented Micos cavefish.

    dataset.keywords: ocular and cutaneous albinism type II (Oca2); melanin; regressive phenotypic evolution; epigean; hypogean; mitocho...
  8. Raw filter Images + Grids Dryad

    DateIssued: 06-07-2013

    Description: These are the high-resolution filter images overlain with a "digital" grid". This grid was used to determine the position from which coloration measur...

    dataset.keywords: ocular and cutaneous albinism type II (Oca2); melanin; regressive phenotypic evolution; epigean; hypogean; mitocho...
  9. Data from: MC1R variants affect the expression of melanocortin and melanogenic genes and the association between melanocortin genes and coloration Dryad

    DateIssued: 01-27-2017

    Description: ression of melanogenic-related genes (TYR, TYRP1, OCA2, SLC45A2, KIT, DCT) but also with a lower MC1R expression and a higher expression of ASIP, the MC1R antagonist. More importantly, the expression of PCSK2, responsible for the maturation of the MC1R agonist, α-melanocyte-stimulating hormone, was positively related to pheomelanin content in MC1R white homozygotes but not in individuals carrying the MC1R rufous allele. These findings indicate that MC1R mutations not only alter the expression of melanogenic-related genes but also the association between coloration and the expression of melanocortin genes upstream of MC1R. This suggests that MC1R mutations can modulate the regulation of coloration by the pleiotropic melanocortin genes, potentially decoupling the often-observed associations between coloration and other phenotypes....

  10. Raw Filter Coloration Measurements Dryad

    DateIssued: 06-07-2013

    Description: The first tab of this data file contains the raw "eye dropper" values collected for each of 13 concentric circular grid points in the CMYK color mode....

    dataset.keywords: ocular and cutaneous albinism type II (Oca2); melanin; regressive phenotypic evolution; epigean; hypogean; mitocho...
  11. ADH6_PERMA UniProt:Swiss-Prot

    ID: P41681

    Description: Alcohol dehydrogenase 6 NAD NAD Zinc 1; catalytic Zinc 1; catalytic Zinc 2 Zinc 2 Zinc 2 Zinc 2 Zinc 1; catalytic NAD NAD NAD

    dataset.creators: Bey M.
  12. ADH1_PERMA UniProt:Swiss-Prot

    ID: P41680

    Description: Removed Alcohol dehydrogenase 1 NAD NAD Zinc 1; catalytic Zinc 1; catalytic Zinc 2 Zinc 2 Zinc 2 Zinc 2 Zinc 1; catalytic NAD NAD NAD N-acetylserine N...

    dataset.creators: Bey M.
  13. CCDC 1500195: Experimental Crystal Structure Determination CCDC

    ID: doi:10.5517/CCDC.CSD.CC1MC2DG

    Release Date: 11-16-2016

    dataset.creators: Bey, Sara N.
  14. Crystal structure of the editing domain of threonyl-tRNA synthetase complexed with seryl-3'-aminoadenosine PDB

    ID: PDB:1TKY

    Description: Threonyl-tRNA synthetase (E.C.6.1.1.3)

    dataset.creators: Bey, G.
  15. Crystal structure of the editing domain of threonyl-tRNA synthetase PDB

    ID: PDB:1TJE

    Description: Threonyl-tRNA synthetase (E.C.6.1.1.3)

    dataset.creators: Bey, G.
  16. FRIH_ANAPL UniProt:Swiss-Prot

    ID: P80145

    Description: Ferritin heavy chain

    dataset.creators: Bey F.
  17. Crystal structure of PPARgamma ligand binding domain in complex with tetrabromo-bisphenol A (TBBPA) PDB

    ID: PDB:3OSW

    Description: Peroxisome proliferator-activated receptor gamma

    dataset.creators: Bey, G.
  18. Crystal structure of the editing domain of threonyl-tRNA synthetase complexed with an analog of seryladenylate PDB

    ID: PDB:1TKG

    Description: Threonyl-tRNA synthetase (E.C.6.1.1.3)

    dataset.creators: Bey, G.
  19. Crystal structure of the editing domain of threonyl-tRNA synthetase complexed with serine PDB

    ID: PDB:1TKE

    Description: Threonyl-tRNA synthetase (E.C.6.1.1.3)

    dataset.creators: Bey, G.
  20. The walker-type atpase paby2304 of pyrococcus abyssi PDB

    ID: PDB:2QEN

    Description: walker-type atpase

    dataset.creators: Bey, G.

Displaying 20 of 29 results for "OCA2"