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Displaying 20 of 37 results for "NRIP1"
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  1. RNAi profiling by array of human HEC-1B endometrial tumor cell lines with silencing of NRIP1 ArrayExpress

    ID: E-MTAB-820

    Description: Measuring the effect of silencing of NRIP1 in an endometrial tumour cell line on gene expression.

  2. RNAi profiling by array of human HEC-1B endometrial tumor cell lines with silencing of NRIP1 OmicsDI

    ID: E-MTAB-820

    Date Released: 06-03-2014

    Description: Measuring the effect of silencing of NRIP1 in an endometrial tumour cell line on gene expression.

  3. A mouse Embryonic Stem Cell Bank for inducible overexpression of human chromosome 21 genes ArrayExpress

    ID: E-GEOD-19836

    Description: oarray analysis: Bach1, Erg, Ets2, Gabpa, ZFP295, Nrip1, Olig1, Olig2, Pknox1, 1810007M14Rik, Runx1, Aire, Sim2, Dscr1, DYRK1A, SNF1LK, Ripk4 , Hunk, Pdxk, Pfkl. Each triplicate clone was transcriptionally profiled by microarray analysis using Affymetrix Mouse 430_2 arrays before and after induction (Affymetrix 430A_2 in case of Runx1), yielding six arrays for each overexpression experiment....

  4. Transcription profiling of mouse adipocytes to determine the role of RIP140 in adipocyte differentiation ArrayExpress

    ID: E-MIMR-42

    Description: Title: Gene Expression analysis of the role of RIP140 in adipocyte differentiation Description: RIPKO cells are mouse embryo fibroblasts (MEF) that we...

  5. Expression of microRNAs and their gene targets are dysregulated in pre-invasive breast cancer (mRNA) ArrayExpress

    ID: E-GEOD-24506

    Description: en cell motility (also a target of miR-125b); and NRIP1/RIP140, which modulates the transcriptional activity of the estrogen receptor. Knockdown of the putative oncogenic miRNAs miR-182 and miR-183, both highly over-expressed in DCIS, increased the expression of CBX7 (which regulates E-cadherin expression), DOK4, NMT2, and EGR1. Augmentation of CBX7 by knockdown of miR-182 expression, in turn, positively regulated the expression of E-cadherin, a key protein involved in maintaining normal epithelial cell morphology which is commonly lost during neoplastic progression. Conclusions: These data provide the first miRNA expression profile of normal breast epithelium and of pre-invasive breast carcinoma. Further, we demonstrate that altered miRNA expression can modulate gene expression changes that characterize these early cancers. We conclude that miRNA dysregulation likely plays a substantial role in early breast cancer development. Two total samples were analyzed via Affymetrix U133A. Case numbers correspond to individual patients. Each sample is identified by case number, histologic lesion and corresponding microarray ID....

  6. A mouse Embryonic Stem Cell Bank for inducible overexpression of human chromosome 21 genes BioProject

    ID: PRJNA122055

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: oarray analysis: Bach1, Erg, Ets2, Gabpa, ZFP295, Nrip1, Olig1, Olig2, Pknox1, 1810007M14Rik, Runx1, Aire, Sim2, Dscr1, DYRK1A, SNF1LK, Ripk4 , Hunk, Pdxk, Pfkl. Overall design: Each triplicate clone was transcriptionally profiled by microarray analysis using Affymetrix Mouse 430_2 arrays before and after induction (Affymetrix 430A_2 in case of Runx1), yielding six arrays for each overexpression experiment....
  7. Integrative genomics of gene regulation by estrogen receptors and and coregulators [ChIP-seq] ArrayExpress

    ID: E-GEOD-42348

    Description: The closely related transcription factors (TFs), estrogen receptors ERα and ERβ, regulate divergent gene expression programs and proliferative outco...

  8. Expression of microRNAs and their gene targets are dysregulated in pre-invasive breast cancer (microRNA) ArrayExpress

    ID: E-GEOD-24508

    Description: en cell motility (also a target of miR-125b); and NRIP1/RIP140, which modulates the transcriptional activity of the estrogen receptor. Knockdown of the putative oncogenic miRNAs miR-182 and miR-183, both highly over-expressed in DCIS, increased the expression of CBX7 (which regulates E-cadherin expression), DOK4, NMT2, and EGR1. Augmentation of CBX7 by knockdown of miR-182 expression, in turn, positively regulated the expression of E-cadherin, a key protein involved in maintaining normal epithelial cell morphology which is commonly lost during neoplastic progression. Conclusions: These data provide the first miRNA expression profile of normal breast epithelium and of pre-invasive breast carcinoma. Further, we demonstrate that altered miRNA expression can modulate gene expression changes that characterize these early cancers. We conclude that miRNA dysregulation likely plays a substantial role in early breast cancer development. The expression of 365 microRNAs were measured in 19 total samples via multiplex reverse transcription PCR using the TaqMan Human MicroRNA Low Density Array. Patients age ranged from 42-75. Equal amounts of total RNA from 9 reduction mammoplasty samples (age range 42-75) were combined into a pooled RM control (PRM), this sample was run in triplicate. Remaining 16 samples consist of matched samples of ductal carcinoma in situ and adjacent histologically normal breast epithelium, these are identified by case number and histologic lesion....

  9. Genomic Analysis of Paired Endometrial Cancer Primaries and Metastases BioProject

    ID: PRJNA322360

    Access Type: download

    dataset.description: uding mutations in the estrogen receptor cofactor NRIP1 in 12% of patients. We found that likely driver events tended to be shared by primary and metastatic tissue-samples, with notable exceptions such as ARID1A mutations. Phylogenetic analyses in cases with multiple metastases indicated these metastases typically arose from... (for more see dbGaP study page.)...
  10. NR2C1_MACFA UniProt:Swiss-Prot

    ID: Q95K90

    Description: eraction with KAT2B Required for interaction with NRIP1 Phosphoserine Phosphoserine Phosphothreonine Phosphothreonine; by MAPK1 Phosphoserine; by PKC Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)...

  11. NR2C1_RAT UniProt:Swiss-Prot

    ID: Q8VIJ4

    Description: eraction with KAT2B Required for interaction with NRIP1 Phosphoserine Phosphoserine Phosphothreonine Phosphothreonine; by MAPK1 Phosphoserine; by PKC Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)...

  12. Expression of microRNAs and their gene targets are dysregulated in pre-invasive breast cancer (mRNA) BioProject

    ID: PRJNA133519

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: en cell motility (also a target of miR-125b); and NRIP1/RIP140, which modulates the transcriptional activity of the estrogen receptor. Knockdown of the putative oncogenic miRNAs miR-182 and miR-183, both highly over-expressed in DCIS, increased the expression of CBX7 (which regulates E-cadherin expression), DOK4, NMT2, and EGR1. Augmentation of CBX7 by knockdown of miR-182 expression, in turn, positively regulated the expression of E-cadherin, a key protein involved in maintaining normal epithelial cell morphology which is commonly lost during neoplastic progression. Conclusions: These data provide the first miRNA expression profile of normal breast epithelium and of pre-invasive breast carcinoma. Further, we demonstrate that altered miRNA expression can modulate gene expression changes that characterize these early cancers. We conclude that miRNA dysregulation likely plays a substantial role in early breast cancer development. Overall design: Two total samples were analyzed via Affymetrix U133A. Case numbers correspond to individual patients. Each sample is identified by case number, histologic lesion and corresponding microarray ID....
  13. NR2C1_BOVIN UniProt:Swiss-Prot

    ID: A0JNE3

    Description: eraction with KAT2B Required for interaction with NRIP1 Phosphoserine Phosphoserine Phosphothreonine Phosphothreonine; by MAPK1 Phosphoserine; by PKC Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)...

  14. NR2C1_PONAB UniProt:Swiss-Prot

    ID: Q5RCZ5

    Description: eraction with KAT2B Required for interaction with NRIP1 Phosphoserine Phosphoserine Phosphothreonine Phosphothreonine; by MAPK1 Phosphoserine; by PKC Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)...

  15. Crystal structure of the orphan nuclear receptor RORalpha ligand-binding domain in complex with 4alpha-caboxyl, 4beta-methyl-zymosterol (4ACD8) PDB

    ID: PDB:4S15

    Description: Nuclear receptor ROR-alpha, Nuclear receptor-interacting protein 1

  16. A mouse Embryonic Stem Cell Bank for inducible overexpression of human chromosome 21 genes OmicsDI

    ID: E-GEOD-19836

    Date Released: 03-27-2012

    Description: oarray analysis: Bach1, Erg, Ets2, Gabpa, ZFP295, Nrip1, Olig1, Olig2, Pknox1, 1810007M14Rik, Runx1, Aire, Sim2, Dscr1, DYRK1A, SNF1LK, Ripk4 , Hunk, Pdxk, Pfkl. Each triplicate clone was transcriptionally profiled by microarray analysis using Affymetrix Mouse 430_2 arrays before and after induction (Affymetrix 430A_2 in case of Runx1), yielding six arrays for each overexpression experiment....

  17. Crystal structure of the orphan nuclear receptor RORgamma ligand-binding domain in complex with 4alpha-caboxyl, 4beta-methyl-zymosterol (4ACD8) PDB

    ID: PDB:4S14

    Description: Nuclear receptor ROR-gamma, Nuclear receptor-interacting protein 1

  18. Interphase condensins regulate ligand-depedent enhancer activation (ChIP-seq) BioProject

    ID: PRJNA263508

    Keywords: Epigenomics

    Access Type: download

  19. Integrative genomics of gene regulation by estrogen receptors and and coregulators [ChIP-seq] BioProject

    ID: PRJNA181136

    Keywords: Epigenomics

    Access Type: download

  20. Integrative genomics of gene and metabolic regulation by estrogen receptors α and β and coregulators [expression] ArrayExpress

    ID: E-GEOD-42347

    Description: The closely related transcription factors (TFs), estrogen receptors ERα and ERβ, regulate divergent gene expression programs and proliferative outco...


Displaying 20 of 37 results for "NRIP1"