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Displaying 20 of 64 results for "NRCAM"
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  1. Human thymic epithelial cell: untransfected control vs. scramble-siRNA transfected vs. CD49e-siRNA transfected BioProject

    ID: PRJNA119437

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. NMR solution structure of human FNIII domain 2 of NCAM PDB

    ID: PDB:5LKN

    Description: Neural cell adhesion molecule 1

  3. Investigation of colominic acid effects on immortalized Schwann cells ArrayExpress

    ID: E-GEOD-14944

    Description: ysialic acid (PSA), which has – attached to the neuronal cell adhesion molecule (NCAM) – emerged as particulate attractive candidate for promoting morphological plasticity of axonal processes during axonal path finding and activity-dependent remodelling. For this purpose self-spotted microarrays with 352 neurospecific genes were hybrid...

  4. Transcription profiling of human perisylvian cerebral cortical patterning ArrayExpress

    ID: E-GEOD-9335

    Description: posterior peri-sylvian cortices in many facets of human-cognitive specializations, including language, little is known about the developmental patterning of these regions in human brain. We performed a genome-wide a...

  5. Investigation of colominic acid effects on immortalized Schwann cells BioProject

    ID: PRJNA111989

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ysialic acid (PSA), which has – attached to the neuronal cell adhesion molecule (NCAM) – emerged as particulate attractive candidate for promoting morphological plasticity of axonal processes during axonal path finding and activity-dependent remodelling. For this purpose self-spotted microarrays with 352 neurospecific genes were hybridiz...
  6. Crystal Structure of domain VI and LE1 of human Netrin-G2 PDB

    ID: PDB:3TBD

    Description: Netrin-G2

  7. Genome-wide analyses of human perisylvian cerebral cortical patterning BioProject

    ID: PRJNA103015

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Genome-wide analyses of human perisylvian cerebral cortical patterning - GPL96 GEMMA

    ID: 1606

    Keywords: functional genomics

    Description: posterior peri-sylvian cortices in many facets of human-cognitive specializations, including language, little is known about the developmental patterning of these regions in human brain. We performed a genome-wide a...

  9. Gene expression profile for L1CAM knockdown in esophageal squamous carcinoma cell BioProject

    ID: PRJNA341332

    Keywords: Transcriptome or Gene expression

    Access Type: download

  10. Genome-wide analyses of human perisylvian cerebral cortical patterning - GPL885 GEMMA

    ID: 1607

    Keywords: functional genomics

    Description: posterior peri-sylvian cortices in many facets of human-cognitive specializations, including language, little is known about the developmental patterning of these regions in human brain. We performed a genome-wide a...

  11. Immunomagnetic purification of mES derived neuronal precursors increases neuronal migration and differentiation in vivo BioProject

    ID: PRJNA150721

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. Immunomagnetic purification of mES derived neuronal precursors increases neuronal migration and differentiation in vivo ArrayExpress

    ID: E-GEOD-35125

    Description: lished protocols for differentiation of mouse and human pluripotent stem cells into specific neural subpopulations generate a considerable cellular heterogeneity that hampers experimental an...

  13. c-JUN REPROGRAMS SCHWANN CELLS OF INJURED NERVES TO GENERATE A REPAIR CELL ESSENTIAL FOR REGENERATION BioProject

    ID: PRJNA168482

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. Profiling data on the developing olfactory/GnRH system reveal cellular and molecular pathways potentially relevant for the Kallmann syndrome ArrayExpress

    ID: E-GEOD-52800

    Description: s differentially expressed during development are neuronal differentiation, extracellular remodelling and cell adhesion. From the analysis of Dlx5 mutant tissues we identify about 120 genes with a prevalence of intermediate filaments, cell signalling, epithelial and neuronal differentiation. Filtering for true OE expression and for the presence of Dlx5 binding sites, yielded twenty genes, of the following categories: 1) transmembrane adhesion/receptor molecules, 2) axon-glia interaction molecules, 3) synaptic proteins, 4) scaffold/adapter for signalling molecules. To functionally analyze these genes in vivo, we used three zebrafish fluorescent reporter zebrafish strains, in which we monitored early phases of olfactory/GnRH development upon gene downmodulation. The depletion of three (of five) Dlx5 targets affected axonal extension and targeting, while two (of two) altered GnRH neuron position and neurite organization. In one experiment we compare the olfactrory sensory epithelium from wild-type embryos, at three times of development, i.e. E11.5, E12.5 and E14.5. In a second experiment we compare the olfactory sensory epithelium from wild-type embryo with that from Dlx5 knock-out embryos, at the age E12.5...

  15. Transcription profiling of human high grade gliomas with a 1p19q codeletion or with EGRF amplification ArrayExpress

    ID: E-MEXP-1507

    Description: en the two types of gliomas and the expression of neuronal genes in gliomas with 1p19q codeletion were both validated in an independent series of 16 gliomas using real-time RT-PCR with a set of 22 genes differentiating the two groups of gliomas (AKR1C3, ATOH8, BMP2, C20orf42, CCNB1, CDK2, CHI3L1, CTTNBP2, DCX, EGFR, GALNT13, GBP1, IGFBP2, IQGAP1, L1CAM, NCAM1, NOG, OLIG2, PDPN, PLAT, POSTN, RNF135). Immunohistochemical study of the most differentially expressed neuronal gene, alpha-internexin, clearly differentiated the two groups of gliomas, with 1p19q codeletion gliomas showing specific staining in tumor cells. These findings provide evidence for neuronal differentiation in oligodendrogliomas with 1p19q codeletion and support the hypothesis that the cell of origin for gliomas with 1p19q codeletion could be a bi-potential progenitor cell, able to give rise to both neurons and oligodendrocytes....

  16. TRF2 Inhibition-Mediated Degradation Derepresses the Neuronal Differentiation Program BioProject

    ID: PRJNA99295

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. Profiling data on the developing olfactory/GnRH system reveal cellular and molecular pathways potentially relevant for the Kallmann syndrome. BioProject

    ID: PRJNA230053

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: s differentially expressed during development are neuronal differentiation, extracellular remodelling and cell adhesion. From the analysis of Dlx5 mutant tissues we identify about 120 genes with a prevalence of intermediate filaments, cell signalling, epithelial and neuronal differentiation. Filtering for true OE expression and for the presence of Dlx5 binding sites, yielded twenty genes, of the following categories: 1) transmembrane adhesion/receptor molecules, 2) axon-glia interaction molecules, 3) synaptic proteins, 4) scaffold/adapter for signalling molecules. To functionally analyze these genes in vivo, we used three zebrafish fluorescent reporter zebrafish strains, in which we monitored early phases of olfactory/GnRH development upon gene downmodulation. The depletion of three (of five) Dlx5 targets affected axonal extension and targeting, while two (of two) altered GnRH neuron position and neurite organization. Overall design: In one experiment we compare the olfactrory sensory epithelium from wild-type embryos, at three times of development, i.e. E11.5, E12.5 and E14.5. In a second experiment we compare the olfactory sensory epithelium from wild-type embryo with that from Dlx5 knock-out embryos, at the age E12.5...
  18. Transcription profiling of human perisylvian cerebral cortical patterning OmicsDI

    ID: E-GEOD-9335

    Date Released: 05-02-2014

    Description: posterior peri-sylvian cortices in many facets of human-cognitive specializations, including language, little is known about the developmental patterning of these regions in human brain. We performed a genome-wide a...

  19. c-JUN REPROGRAMS SCHWANN CELLS OF INJURED NERVES TO GENERATE A REPAIR CELL ESSENTIAL FOR REGENERATION ArrayExpress

    ID: E-GEOD-38693

    Description: mammals. Using mice with inactivation of Schwann cell c-Jun, we show that the injury response involves c-Jun dependent natural reprograming of differentiated cells to generate a distinct Schwann cell state specialized to promote regeneration. Transected distal stumps of c-Jun mutants show 172 disregulated genes, resulting in abnormal expression...

  20. To identify specific glycosylated structures on brain endothelial cells that mediate rolling, adhesion, and diapedesis of leukocytes in the brain ArrayExpress

    ID: E-GEOD-29932

    Description: ic perivascular endfeet, pericytes, microglia and neuronal processes that have been shown to contribute to barrier function1. In essence, the brain endothelium limits both transcellular and paracellular passage of cells and molecules into the central nervous system (CNS). Transcellular passage of hydrophilic molecules is limited due to a low rate of transcytotic vesicles, an extremely low pinocytotic activity, expression of active efflux transporters, and high metabolic a...


Displaying 20 of 64 results for "NRCAM"