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Displaying 20 of 1,271 results for "NRAS"
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  1. Deciphering KRAS and NRAS mutated clones dynamics in MLL-AF4 pediatric leukemia by ultra deep sequencing analysis BioProject

    ID: PRJNA310245

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. NRAS Isoform 5 PDB

    ID: PDB:2N9C

    Description: GTPase NRas

  3. Gene expression profiling of oncogenic NRAS driven mouse melanomas that have developed resistance to NRAS withdrawal BioProject

    ID: PRJNA225793

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. Gene expression data from NRAS-driven CNS-PNET zebrafish brain tumors and normal brain. BioProject

    ID: PRJNA319956

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Comparison of the genetic extinction of NRAS to pharmacological MEK inhibition in an inducible mouse model of melanoma BioProject

    ID: PRJNA172204

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Crystal structure of the human NRAS GTPase bound with GDP PDB

    ID: PDB:3CON

    Description: GTPase NRas

  7. N-arachidonoyl dopamine or vehicle control treated NRAS-G12D transformed Ba/F3 cells expression data BioProject

    ID: PRJNA342163

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Germline NRAS mutation causes a novel human autoimmune lymphoproliferative syndrome BioProject

    ID: PRJNA100453

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. c mutations in pyrosequencing signals: a case for NRAS analysis... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3622019_D2

    Release Date: 12-15-2016

    Description: Additional file 1. Source code of AdvISER-PYRO-SMQ. The source code for the new R package which implements the AdvISER-PYRO-SMQ algorithm.

  10. Effect of DNMT3A R882H mutation or WT on gene expression in hematopoietic stem/progenitor cells with NRAS G12D co-transduction (Microarray) ArrayExpress

    ID: E-GEOD-71437

    Description: A-R882H) cooperates with constitutively activated RAS in transforming murine hematopoietic stem/progenitor cells (HSPCs) ex vivo and inducing acute leukemias in vivo. DNMT3A-R882H potentiates aberrant transactivation of ‘stemness’ gene expression programs, notably transcription factors Meis1, Hox-A, Mn1 and Mycn. Mechanistically, R882-mutated DNMT3A directly binds to cis-regulatory elements of these genes...

  11. Gene expression profiling of oncogenic NRAS driven mouse melanomas that have developed resistance to NRAS withdrawal ArrayExpress

    ID: E-GEOD-51906

    Description: ant tumors following genetic inhibition of mutant NRAS. Analysis of tumors that became resistant to NRAS suppression revealed that the most common mechanism of resistance was overexpression of the Met receptor tyrosine kinase (RTK). Importantly, inhibition of Met overcomes NRAS resistance in this context. Analysis of NRAS mutant human melanoma cells revealed that inhibition of MEK is also associated with adaptive RTK signaling. Furthermore, co-inhibition of RTK signaling and MEK overcomes acquired MEK inhibitor resistance in NRAS mutant melanoma. These data suggest that combined inhibition of RTK and MEK signaling is a rational therapeutic strategy in mutant NRAS driven melanoma. Reversible NRAS Q61R expressi...

  12. A timecourse analysis of the genetic extinction of NRAS in an inducible mouse model of melanoma. BioProject

    ID: PRJNA172205

    Keywords: Transcriptome or Gene expression

    Access Type: download

  13. capes of hematopoietic stem/progenitor cells with NRAS G12D co-transduction (ChIP-seq)... BioProject

    ID: PRJNA291344

    Keywords: Epigenomics

    Access Type: download

  14. Oncogenic potential of RAS isoforms in melanocytes BioProject

    ID: PRJNA100677

    Keywords: Transcriptome or Gene expression

    Access Type: download

  15. Effect of DNMT3A R882H mutation or WT on gene expression in hematopoietic stem/progenitor cells with NRAS G12D co-transduction (Microarray) BioProject

    ID: PRJNA291210

    Keywords: Transcriptome or Gene expression

    Access Type: download

  16. terns of hematopoietic stem/progenitor cells with NRAS G12D co-transduction (eRRBS)... BioProject

    ID: PRJNA291346

    Keywords: Epigenomics

    Access Type: download

  17. Synergistic effects of eIF4A and MEK inhibitors on proliferation of NRAS-mutant melanoma cell lines Figshare

    ID: doi:10.6084/M9.FIGSHARE.3573510.V2

    Release Date: 09-09-2016

    Description: Activating mutations of the NRAS (neuroblastoma rat sarcoma viral oncogene) protein kinase, present in...

  18. Regulators of NRAS-mediated transformation and melanoma tumor maintenance BioProject

    ID: PRJNA287169

    Keywords: Transcriptome or Gene expression

    Access Type: download

  19. Oncogenic NRAS Signaling Differentially Regulates Survival and Proliferation in Melanoma ArrayExpress

    ID: E-GEOD-39987

    Description: GSE39984: Comparison of the genetic extinction of NRAS to pharmacological MEK inhibition in an inducible mouse model of melanoma [4 days post-treatment] GSE39985: A timecourse analysis of the genetic extinction of NRAS in a...

  20. capes of hematopoietic stem/progenitor cells with NRAS G12D co-transduction (ChIP-seq)... ArrayExpress

    ID: E-GEOD-71472

    Description: A-R882H) cooperates with constitutively activated RAS in transforming murine hematopoietic stem/progenitor cells (HSPCs) ex vivo and inducing acute leukemias in vivo. DNMT3A-R882H potentiates aberrant transactivation of ‘stemness’ gene expression programs, notably transcription factors Meis1, Hox-A, Mn1 and Mycn. Mechanistically, R882-mutated DNMT3A directly binds to cis-regulatory elements of these...


Displaying 20 of 1,271 results for "NRAS"