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Displaying 20 of 45 results for "NR4A3"
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  1. Effect of NR4A3 siRNA treatment on gene expression of islet derived hybrid cell of 1.1B4 BioProject

    ID: PRJNA343006

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Nr4a1 and Nr4a3 upregulate cell cycle genes upregulated in the Nkx6.1 β-cell proliferation pathway BioProject

    ID: PRJNA238471

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Nr4a1 and Nr4a3 upregulate cell cycle genes upregulated in the Nkx6.1 beta-cell proliferation pathway ArrayExpress

    ID: E-GEOD-55078

    Description: e that Nkx6.1 induces expression of the Nr4a1 and Nr4a3 orphan nuclear receptors, and that these factors are both necessary and sufficient for Nkx6.1-mediated β-cell proliferation. Overexpression of the Nr4a receptors results in increased expression of key cell cycle inducers E2F1 and cyclin E1. Furthermore, Nr4a receptors induce components of the anaphase-promoting complex, including Ube2c. We set up a microarray using primary rat islets that wer...

  4. ydroxymethylation of the exercise-responsive gene Nr4a3... BioProject

    ID: PRJNA347343

    Access Type: download

  5. Nr4a1 and Nr4a3 upregulate cell cycle genes upregulated in the Nkx6.1 beta-cell proliferation pathway OmicsDI

    ID: E-GEOD-55078

    Date Released: 08-03-2015

    Description: e that Nkx6.1 induces expression of the Nr4a1 and Nr4a3 orphan nuclear receptors, and that these factors are both necessary and sufficient for Nkx6.1-mediated β-cell proliferation. Overexpression of the Nr4a receptors results in increased expression of key cell cycle inducers E2F1 and cyclin E1. Furthermore, Nr4a receptors induce components of the anaphase-promoting complex, including Ube2c. We set up a microarray using primary rat islets that wer...

  6. Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors BioProject

    ID: PRJNA238469

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Nkx6.1 regulates islet beta-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors ArrayExpress

    ID: E-GEOD-55077

    Description: e that Nkx6.1 induces expression of the Nr4a1 and Nr4a3 orphan nuclear receptors, and that these factors are both necessary and sufficient for Nkx6.1-mediated beta-cell proliferation. Consistent with this finding, global knockout of Nr4a1 results in a decrease in beta-cell area in neonatal and young mice. Overexpression of Nkx6.1 and the Nr4a receptors results in increased expression of key cell cycle inducers E2F1 and cyclin E1. Furthermore, Nkx6.1 and Nr4a receptors induce components of the anaphase-promoting complex, including Ube2c, resulting in degradation of the cell cycle inhibitor p21CIP1. These stud...

  8. ydroxymethylation of the exercise-responsive gene Nr4a3 [Bisulfite-Seq]... BioProject

    ID: PRJNA347416

    Keywords: Epigenomics

    Access Type: download

  9. HMF3A_RNAi ArrayExpress

    ID: E-GEOD-690

    Description: vation. The genes chosen for targeting were BTG2, NR4A3, DUSP1, PHLDA1 and STACb. Keywords = LT antigen Keywords = senescence Keywords = fibroblast Keywords = BTG2 Keywords = DUSP1 Keywords = MKP-1 Keywords = NR4A3 Keywords = STAC Keywords = PHLDA1 Keywords = RNAi...

  10. ydroxymethylation of the exercise-responsive gene Nr4a3 [RNA-Seq]... BioProject

    ID: PRJNA347417

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. HMF3A_RNAi BioProject

    ID: PRJNA87643

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: vation. The genes chosen for targeting were BTG2, NR4A3, DUSP1, PHLDA1 and STACb. Keywords = LT antigen Keywords = senescence Keywords = fibroblast Keywords = BTG2 Keywords = DUSP1 Keywords = MKP-1 Keywords = NR4A3 Keywords = STAC Keywords = PHLDA1 Keywords = RNAi Keywords: other...
  12. NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival BioProject

    ID: PRJNA374852

    Keywords: Transcriptome or Gene expression

    Access Type: download

  13. Transcription profiling of human NOR1- and EWS/NOR1-overexpressing 293 cells ArrayExpress

    ID: E-GEOD-11185

    Description: To examine the differences between NOR1 and its fusion gene product EWS/NOR1, we compared the gene expression profiles of NOR1- and EWS/NOR1-overexpre...

  14. Differences between NOR1 and EWS/NOR1 BioProject

    ID: PRJNA106887

    Keywords: Transcriptome or Gene expression

    Access Type: download

  15. HMF3A_RNAi OmicsDI

    ID: E-GEOD-690

    Date Released: 03-27-2012

    Description: vation. The genes chosen for targeting were BTG2, NR4A3, DUSP1, PHLDA1 and STACb. Keywords = LT antigen Keywords = senescence Keywords = fibroblast Keywords = BTG2 Keywords = DUSP1 Keywords = MKP-1 Keywords = NR4A3 Keywords = STAC Keywords = PHLDA1 Keywords = RNAi...

  16. Nkx6.1 regulates islet beta-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors OmicsDI

    ID: E-GEOD-55077

    Date Released: 08-03-2015

    Description: e that Nkx6.1 induces expression of the Nr4a1 and Nr4a3 orphan nuclear receptors, and that these factors are both necessary and sufficient for Nkx6.1-mediated beta-cell proliferation. Consistent with this finding, global knockout of Nr4a1 results in a decrease in beta-cell area in neonatal and young mice. Overexpression of Nkx6.1 and the Nr4a receptors results in increased expression of key cell cycle inducers E2F1 and cyclin E1. Furthermore, Nkx6.1 and Nr4a receptors induce components of the anaphase-promoting complex, including Ube2c, resulting in degradation of the cell cycle inhibitor p21CIP1. These stud...

  17. Effect of H2O2 treatment on gene expression of islet derived hybrid cell of 1.1B4 ArrayExpress

    ID: E-GEOD-83369

    Description: ed with control sample. HMOX1, EGR1, IGF, IL8 and NR4A3 were strongly up-regulated Gene regulation associated with antioxidant defense system in pancreatic beta cells still needs to be elucidated, we analyzed the genes expression with Agilent micro-array after 4 hours of 100mM H2O2 treatment by one color method, and found 2903 genes were up-regulated and 2283 genes were down regulated. Changes of som...

  18. Influence of muscle activity on paralyzed muscle ArrayExpress

    ID: E-GEOD-63423

    Description: ift muscle toward an oxidative phenotype (PGC-1a, NR4A3, IFRD1, ABRA, PDK4). However, chronic training increased the mRNA expression of specific metabolic pathway genes (BRP44, BRP44L, SDHB, ACADVL), mitochondrial fission and fusion genes (MFF, MFN1, MFN2), and slow muscle fiber genes (MYH6, MYH7, MYL3, MYL2).Furthermore, regulating these same pathways may be critical to developing efficient activity protocols to reduce the prevalence of diabetes in people with longstanding paralysis from SCI. We analyzed skeletal muscle using the Affymetrix Human Exon 1.0 ST platform. Array data was processed by Partek Genomic Suites....

  19. Effect of H2O2 treatment on gene expression of islet derived hybrid cell of 1.1B4 BioProject

    ID: PRJNA325724

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ed with control sample. HMOX1, EGR1, IGF, IL8 and NR4A3 were strongly up-regulated Overall design: Gene regulation associated with antioxidant defense system in pancreatic beta cells still needs to be elucidated, we analyzed the genes expression with Agilent micro-array after 4 hours of 100mM H2O2 treatment by one color method, and found 2903 genes were up-regulated and 2283 genes were down regulated...
  20. Transcription profiling of human CD34+ subsets in chronic phase CML and healthy individuals ArrayExpress

    ID: E-GEOD-11889

    Description: o found abrogation of nuclear receptors NR4A1 and NR4A3, and decreased expression of c-Jun and JunB. Re-expression of c-Jun and JunB in CD34+ cells from CML patients was achieved by co-transfection of NR4A1 and NR4A3. Moreover, we functionally corroborated a decreased adhesion capacity of the CML HSC. Taken together, these findings help to explain the hematological phenotype of CML patients in chronic phase. Experiment Overall Design: CD34+ subsets of 6 patients with chronic phase CML and 5 healthy volunteers were analysed by means of gene expression profiling with the Affymetrix HU-133A 2.0 array...


Displaying 20 of 45 results for "NR4A3"