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Displaying 20 of 418 results for "NQO1"
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  1. NQO1 regulates inflammatory signaling BioProject

    ID: PRJNA252018

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Crystal Structure of NAD(P)H dehydrogenase, quinone 1 complexed with a chemotherapeutic naphthoquinone E6a PDB

    ID: PDB:5EAI

    Description: NAD(P)H dehydrogenase [quinone] 1 (E...

  3. Crystal Structure of Holo NAD(P)H dehydrogenase, quinone 1 PDB

    ID: PDB:5EA2

    Description: NAD(P)H dehydrogenase [quinone] 1 (E...

  4. X-ray Crystal structure of NAD(P)H: Quinone Oxidoreductase-1 (NQO1) bound to the coumarin-based inhibitor AS1 PDB

    ID: PDB:3JSX

    Description: NAD(P)H dehydrogenase [quinone] 1 (E...

  5. NQO1 regulates inflammatory signaling ArrayExpress

    ID: E-GEOD-58336

    Description: NQO1 silencing by a specific shRNA against NQO1 increased migration and hormone-independent survival in hormone-...

  6. Crystal Structure of NQO1 with Dicoumarol PDB

    ID: PDB:2F1O

    Description: NAD(P)H dehydrogenase [quinone] 1 (E...

  7. Comparison of gene expression profiles of anaplastic glioma with or without the mutated IDH1/2 gene BioProject

    ID: PRJNA230506

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ls of representative NRF2 target genes, including NQO1, HMOX1, GCLM, TXNRD1, and PRDX1. Overall design: 12 anaplastic gliomas with or without mutated IDH1/2....
  8. CRYSTAL STRUCTURE OF THE H80R VARIANT OF NQO1 BOUND TO DICOUMAROL PDB

    ID: PDB:5FUQ

    Description: NAD(P)H DEHYDROGENASE [QUINONE] 1 (E...

  9. Comparison of gene expression profiles of anaplastic glioma with or without the mutated IDH1/2 gene ArrayExpress

    ID: E-GEOD-52942

    Description: ls of representative NRF2 target genes, including NQO1, HMOX1, GCLM, TXNRD1, and PRDX1. 12 anaplastic gliomas with or without mutated IDH1/2....

  10. NAs, DMSO, or CXCR2, PTGIS, HAS1, PFKFB3, JAK, or NQO1 inhibitor... ArrayExpress

    ID: E-GEOD-22917

    Description: treated with JAK, PTGIS, PFKFB3, CXCR2, HAS1, or NQO1 inhibitor (all of which decreased Stat3 transcriptional activity in Hs 578T cells except for the NQO1 inhibitor), inhibitor treatment vehicle alone (DMSO), STAT3 siRNAs, or non-targeting siRNAs. Using the resulting data, we identified a gene signature that was significantly regulated by STAT3 siRNAs...

  11. NAs, DMSO, or CXCR2, PTGIS, HAS1, PFKFB3, JAK, or NQO1 inhibitor... BioProject

    ID: PRJNA127973

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. Crystal structure of the R139W variant of human NAD(P)H:quinone oxidoreductase PDB

    ID: PDB:5A4K

    Description: NAD(P)H DEHYDROGENASE [QUINONE] 1 (E...

  13. Crystal structure of the complex of the P187S variant of human NAD(P) H:quinone oxidoreductase with Cibacron blue at 2.7 A resolution PDB

    ID: PDB:4CF6

    Description: NAD(P)H DEHYDROGENASE [QUINONE] 1 (E...

  14. Crystal structure of the complex of the P187S variant of human NAD(P) H:quinone oxidoreductase with dicoumarol at 2.2 A resolution PDB

    ID: PDB:4CET

    Description: NAD(P)H DEHYDROGENASE [QUINONE] 1 (E...

  15. NQO1_CAVPO UniProt:Swiss-Prot

    ID: Q8CHK7

    Description: NAD(P)H dehydrogenase [quinone] 1 FA...

  16. Transcription profiling of human neuroblastoma cell line IMR-32 overexpressiong SQSTM1 and DPP3 to identify activators for the antioxidant response el... ArrayExpress

    ID: E-GEOD-6451

    Description: vation. A subset of cDNAs, including sequestosome 1 (SQSTM1) and dipeptidylpeptidase III (DPP3), activated the ARE in primary mouse-derived cortical neurons. Overexpression of SQSTM1 and DPP3 in IMR-32 cells stimulated NRF2 nuclear translocation and led to increased levels of NAD(P)H:quinone oxidoreductase 1 (NQO1), a protein which is transcriptionally regulated by the ARE. When transfected into IMR-32 neuroblastoma cells that were depleted of transcription factor NRF2 by RNA interference, SQSTM1 and DPP3 were unable to activate the ARE or induce NQO1 expression, indicating that the ARE activation upon ectopic e...

  17. NQO1_PONAB UniProt:Swiss-Prot

    ID: Q5RD31

    Description: Removed NAD(P)H dehydrogenase [quinone] 1 FA...

  18. NQO1 regulates inflammatory signaling OmicsDI

    ID: E-GEOD-58336

    Date Released: 09-01-2014

    Description: NQO1 silencing by a specific shRNA against NQO1 increased migration and hormone-independent survival in hormone-...

  19. Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane treated human breast epithelial cells BioProject

    ID: PRJNA138799

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: mic responses in both the SFN treatment (R=0.679, P<0.05) and KEAP1 knockdown (R=0.853, P<0.05) experiments. Common pathways for SFN treatment and KEAP1 knockdown were xenobiotic metabolism and antioxidants, glutathione metabolism, carbohydrate metabolism and NADH/NADPH regeneration. Moreover, these pathways were most prominent in both the transcriptomic and proteomic analyses. The aldo-keto reductase family members, AKR1B10, AKR1C1, AKR1C2 and AKR1C3, as well as NQO1 and ALDH3A1, were highly upregulated at both the transcriptomic and proteomic level. Collectively, these studies served to identify potential biomarkers that can be used in clinical trials to investigate the initial pharmacodynamic action of SFN in the breast. Overall design: MCF10A cells were treated with SFN or had KEAP1 knocked down by siRNA....
  20. Yeast response to the DNA damaging beta-lapachone ArrayExpress

    ID: E-GEOD-15412

    Description: -lap cytotoxicity was shown to be mediated by the NQO1 NAD(P)H dehydrogenase and radical oxygen species (ROS) generation in several tumour cells. To further characterise the molecular effects of b-lap action, we compared the...


Displaying 20 of 418 results for "NQO1"