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Displaying 20 of 184 results for "NLK"
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  1. NLK_BOVIN UniProt:Swiss-Prot

    ID: E1BMN8

    Description: Serine/threonine-protein kinase NLK Protein kinase ATP Required for interaction with TAB2 Sufficient for interaction w...

  2. Neuron-specific deletion of the miRNA-processing enzyme DICER induces severe but transient obesity in mice BioProject

    ID: PRJNA262716

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ated pathways including leptin, somatostatin, and nemo-like kinase signaling, as well as genes involved in feeding and appetite (e.g. Pmch, Neurotensin). A cluster of genes involved in synaptic plasticity was specifically enriched in post-obese mice that did not appear in obese mice. While other studies have identified a role for miRNAs in obesity our model is unique in that it allows for the study of processes involved in reversing obesity. Overall design: Tissues were collected 4 weeks and 8 weeks after induction of dicer gene knock-out. For each tissue (i.e., cortex, hypothalamus, hippocampus) a total of 3 animals per treatment and per time point was used. Genetic modification....
  3. LEF1_RAT UniProt:Swiss-Prot

    ID: Q9QXN1

    Description: -rich Poly-Lys Phosphoserine Phosphothreonine; by NLK Phosphoserine; by NLK Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)...

  4. LEF1_MOUSE UniProt:Swiss-Prot

    ID: P27782

    Description: -rich Poly-Lys Phosphoserine Phosphothreonine; by NLK Phosphoserine; by NLK Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) In isoform 2. Strongly diminishes CTNNB1 b...

  5. NLK_CAEBR UniProt:Swiss-Prot

    ID: A8XSC1

    Description: Serine/threonine kinase NLK Protein kinase ATP Gln-rich His-rich Proton acceptor ATP

  6. STAT3_RAT UniProt:Swiss-Prot

    ID: P52631

    Description: nd PTK6 Phosphothreonine Phosphoserine; by DYRK2, NLK, NEK6, IRAK1, RPS6KA5, ZIPK/DAPK3 and PKC/PRKCE...

  7. STA32_XENLA UniProt:Swiss-Prot

    ID: Q7ZXK3

    Description: Signal transducer and activator of transcription 3.2 SH2 Essential for nuclear import Phosphoserine; by NLK

  8. NLK2_XENTR UniProt:Swiss-Prot

    ID: B1H3E1

    Description: Serine/threonine-protein kinase NLK2 Protein kinase ATP Poly-Gly Proton acceptor ATP

  9. FOXO1_RAT UniProt:Swiss-Prot

    ID: G3V7R4

    Description: nding DNA binding Sufficient for interaction with NLK Required for interaction with RUNX2 Nuclear localization signal Required for interaction with SIRT1 Poly-Ala Pro-rich DNA binding DNA binding DNA binding Phosphothreon...

  10. FOXO1_PIG UniProt:Swiss-Prot

    ID: A4L7N3

    Description: nding DNA binding Sufficient for interaction with NLK Required for interaction with RUNX2 Nuclear localization signal Required for interaction with SIRT1 Ala-rich Pro-rich Poly-Ser DNA binding DNA binding DNA binding Phos...

  11. STA31_XENLA UniProt:Swiss-Prot

    ID: Q9PVX8

    Description: H2 Essential for nuclear import Phosphoserine; by NLK Does not induce t/bra expression; when associated A-728. Induces t/bra expression; when associated with E-728 Inhibits t/bra expression and mesoderm induction Inhibits t/bra express...

  12. MYB_BOVIN UniProt:Swiss-Prot

    ID: P46200

    Description: -T-H motif H-T-H motif Interaction with HIPK2 and NLK Transcriptional activation domain Negative regulatory domain Leucine-zipper N6-acetyllysine N6-acetyllysine Phosphoserine Phosphothreonine...

  13. FOXO1_ICTTR UniProt:Swiss-Prot

    ID: Q810W5

    Description: nding DNA-binding Sufficient for interaction with NLK Required for interaction with RUNX2 Nuclear localization signal Required for interaction with SIRT1 Poly-Ala DNA-binding DNA-binding DNA-binding Phosphothreonine; by P...

  14. STAT3_BOVIN UniProt:Swiss-Prot

    ID: P61635

    Description: nd PTK6 Phosphothreonine Phosphoserine; by DYRK2, NLK, NEK6, IRAK1, RPS6KA5, ZIPK/DAPK3 and PKC/PRKCE...

  15. STAT3_PIG UniProt:Swiss-Prot

    ID: Q19S50

    Description: nd PTK6 Phosphothreonine Phosphoserine; by DYRK2, NLK, NEK6, IRAK1, RPS6KA5, ZIPK/DAPK3 and PKC/PRKCE...

  16. FOXO1_BOVIN UniProt:Swiss-Prot

    ID: E1BPQ1

    Description: nding DNA binding Sufficient for interaction with NLK Required for interaction with RUNX2 Nuclear localization signal Required for interaction with SIRT1 Ala-rich Poly-Ser DNA binding DNA binding DNA binding Phosphothreon...

  17. TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma ArrayExpress

    ID: E-GEOD-15264

    Description: ation of multiple receptors activates the IkappaB kinase (IKK) complex that phosphorylates IkappaB at two specific serine residues, followed by its ubiquitination and proteasomal degradation, thereby releasing NF-kappaB proteins and allowing their nuclear translocation (3). Recently, two studies provided further insights into the molecular mechanisms of IKK activation upon TNF stimulation (4, 5). Activation of the IKK complex and subsequent NF-kappaB activation requires Lys63 polyubiquitination of RIP1, a kinase which is recruited to the receptor upon TNF stimulation. IKK-(NEMO), the regulatory subunit of the IKK complex, specifically recognizes these Lys63-linked polyubiquitins attached to RIP1 and thereby activates IKK and NF-kappaB (4, 5...

  18. NLK_RAT UniProt:Swiss-Prot

    ID: D3ZSZ3

    Description: Serine/threonine-protein kinase NLK Protein kinase ATP Required for interaction with TAB2 Sufficient for interaction w...

  19. NLK_CANLF UniProt:Swiss-Prot

    ID: E2QWQ2

    Description: Serine/threonine-protein kinase NLK Protein kinase ATP Required for interaction with TAB2 Sufficient for interaction w...

  20. TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma BioProject

    ID: PRJNA116491

    Keywords: Variation

    Access Type: download

    dataset.description: ation of multiple receptors activates the IkappaB kinase (IKK) complex that phosphorylates IkappaB at two specific serine residues, followed by its ubiquitination and proteasomal degradation, thereby releasing NF-kappaB proteins and allowing their nuclear translocation (3). Recently, two studies provided further insights into the molecular mechanisms of IKK activation upon TNF stimulation (4, 5). Activation of the IKK complex and subsequent NF-kappaB activation requires Lys63 polyubiquitination of RIP1, a kinase which is recruited to the receptor upon TNF stimulation. IKK-gamma (NEMO), the regulatory subunit of the IKK complex, specifically recognizes these Lys63-linked polyubiquitins attached to RIP1 and thereby activates IKK and NF-kappaB (4, 5...

Displaying 20 of 184 results for "NLK"