NKX2-5 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 202 results for "NKX2-5"
i
  1. Transcription profiling of hearts from Nkx2.5 knockout mice (mouse model of congenital heart disease) at embryonic day 12.5 shows Nkx2.5 is not only cr... ArrayExpress

    ID: E-GEOD-528

    Description: The NK2 family of homeobox genes constitutes a family of transcription factors that play an important role in differ...

  2. TBX5 DB, NKX2.5 HD, ANF DNA Complex PDB

    ID: PDB:4S0H

    Description: T-box transcription factor TBX5, Homeobox protein Nkx-2.5

  3. NKX2.5 Homeodomain dimer bound to ANF-242 DNA PDB

    ID: PDB:3RKQ

    Description: Homeobox protein Nkx-2.5/DNA

  4. Transcriptome of Nkx2-5-null atria BioProject

    ID: PRJNA226638

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. NK2 model of congenital heart disease BioProject

    ID: PRJNA85533

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Transcriptional profile of Nkx2-5 knockin mutant adult hearts BioProject

    ID: PRJNA339723

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Identification of putative targets of Nkx2-5 in Xenopus laevis using gene expression analysis and cross-species annotation BioProject

    ID: PRJNA155215

    Access Type: download

  8. Mus musculus : Analysis of Tbx5, Nkx2-5 and Gata4 genomic occupancy and gene expression in differentiating cardiomyocytes. BioProject

    ID: PRJNA292836

    Keywords: genome sequencing and assembly

    Access Type: download

  9. Genome-wide maps of Nkx2-5 in E11.5 mouse embryonic heart BioProject

    ID: PRJNA190090

    Keywords: Epigenomics

    Access Type: download

  10. Congenital heart disease in Csx/ Nkx2.5 mutant embryos BioProject

    ID: PRJNA85515

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. NKX2-5 mutations causative for congenital heart disease retain functionality and are directed to hundreds of targets BioProject

    ID: PRJNA192669

    Keywords: Epigenomics

    Access Type: download

  12. Next Generation Sequencing Analysis of Wild Type and Hypomorphic Nkx2-5 mutant heart Transcriptomes BioProject

    ID: PRJNA190089

    Keywords: Transcriptome or Gene expression

    Access Type: download

  13. NK2 model of congenital heart disease GEMMA

    ID: 1071

    Keywords: functional genomics

    Description: Lack of the conserved NK2-domain of the cardiac transcription factor Nkx2.5 causes multiple heart defects . The NK2

  14. Identification of putative targets of Nkx2-5 in Xenopus laevis using gene expression analysis and cross-species annotation OmicsDI

    ID: E-GEOD-29791

    Date Released: 12-13-2011

    Description: of cardiac specification is the expression of the homeobox transcription factor Nkx2-5 and its paralogs. While some downstream targets of Nkx2-5 have been discovered, they alone are not sufficient to completely rescue Nkx2-5 knock-downs, suggesting that othe...

  15. Transcriptome of Nkx2-5-null atria OmicsDI

    ID: E-GEOD-52080

    Date Released: 12-23-2014

    Description: Atrial specific knockout of Nkx2-5 results in hyperplastic atria with ASD and conduction defects. To examine how Nkx2-

  16. Transcriptome of Nkx2-5-null atria ArrayExpress

    ID: E-GEOD-52080

    Description: Atrial specific knockout of Nkx2-5 results in hyperplastic atria with ASD and conduction defects. To examine how Nkx2-

  17. Identification of putative targets of Nkx2-5 in Xenopus laevis using gene expression analysis and cross-species. BioProject

    ID: PRJNA140935

    Access Type: download

  18. miR-302-367 regulates cardiomycyte proliferation and differentiation during development BioProject

    ID: PRJNA238214

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: cluster in mouse heart by using R26R-miR-302-367; Nkx2.5-Cre mice. This data set contains the microarrays examining gene expression in the hearts of R26R-miR-302-367; Nkx2.5-Cre mice at postnatal day 14. Overall design: We overexpressed miR-302-367 cluster ...
  19. Transcription profiling by array of tbx5, nkx2-5 or both transcription factor knockouts during early heart formation in mouse OmicsDI

    ID: E-GEOD-77576

    Date Released: 03-14-2016

    Description: between the T-box TF TBX5 and the homeodomain TF NKX2-5 have been proposed as a mechanism for human congenital heart disease. In order to study the role of each TF during heart formation, embryonic stem (ES) cell-derived embryos were generated fro...

  20. mCasz1_conditional knockout BioProject

    ID: PRJNA239462

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: 1 knockout mice to show that ablation of CASZ1 in Nkx2.5-positive cardiomyocytes leads to cardiac hypoplasia, ventricular septal defects and lethality by E13.5. To identify the pathways and networks by which Casz1 regulates cardiomyocyte development, we used RNA-Seq and identified genes involved in cell proliferation are upregulated in Casz1 mutants compared to wild-type littermates. We conclude that Casz1 is essential for cardiac development and has a pivotal role in regulating part of the cardiac transcriptional pro...

Displaying 20 of 202 results for "NKX2-5"