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Displaying 20 of 40 results for "NFKB2"
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  1. crystal structure of the C-terminal domain of p100/NF-kB2 PDB

    ID: PDB:4OT9

    Description: Nuclear factor NF-kappa-B p100 subunit

    gene.name: NFKB2, LYT10
  2. Developmental LTbR synergistically activates TLR4 mediated inflammatory RelA/NF-kB response OmicsDI

    ID: E-GEOD-62301

    Date Released: 05-10-2015

    Description: nonical signaling targets canonical TLR4 induced, nfkb2 encoded p100 not only to deplete inhibitory IkBd/(p100)2, but also to supplement RelA:p52/NF-kB dimers. Robust crosstalk in the gut epithelial cells are important, as crosstalk-defective nfkb2-/- mice succumbed to gut infection by Citrobacter rodentium due to hypo-inflammatory responses. Finally, we present evidence for a crosstalk motif that integrates tissue microenvironment derived developmental cues to ameliorate the pathogen response. Total RNA from WT early passage MEFs stimulated with ligands LPS, L...

  3. The NFKB inducing kinase (NIK) modulates hematopoiesis during stress BioProject

    ID: PRJNA268831

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: inducing kinase, NIK, and the downstream molecule NFkB2) had a defect in response to stressors such as supraphysiological doses of cytokines, chemotherapy and hematopoietic transplantation. NIK-deficient mice had peripheral blood and bone marrow leukocyte numbers within normal ranges (except for the already reported defects in B-cell maturation), however, HSCs showed significantly slower expansion capacity in in vitro cultures compared to wild ty...
  4. Developmental LTbR synergistically activates TLR4 mediated inflammatory RelA/NF-kB response BioProject

    ID: PRJNA263799

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: nonical signaling targets canonical TLR4 induced, nfkb2 encoded p100 not only to deplete inhibitory IkBd/(p100)2, but also to supplement RelA:p52/NF-kB dimers. Robust crosstalk in the gut epithelial cells are important, as crosstalk-defective nfkb2-/- mice succumbed to gut infection by Citrobacter rodentium due to hypo-inflammatory responses. Finally, we present evidence for a crosstalk motif that integrates tissue microenvironment derived developmental cues to ameliorate the pathogen response. Overall design: Total RNA from WT early passage MEFs stimulated wit...
  5. Developmental LTbR synergistically activates TLR4 mediated inflammatory RelA/NF-kB response ArrayExpress

    ID: E-GEOD-62301

    Description: nonical signaling targets canonical TLR4 induced, nfkb2 encoded p100 not only to deplete inhibitory IkBd/(p100)2, but also to supplement RelA:p52/NF-kB dimers. Robust crosstalk in the gut epithelial cells are important, as crosstalk-defective nfkb2-/- mice succumbed to gut infection by Citrobacter rodentium due to hypo-inflammatory responses. Finally, we present evidence for a crosstalk motif that integrates tissue microenvironment derived developmental cues to ameliorate the pathogen response. Total RNA from WT early passage MEFs stimulated with ligands LPS, L...

  6. NFKB2_XENLA UniProt:Swiss-Prot

    ID: O73630

    Description: Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p52 subunit RHD ANK 1 ANK 2 ANK 3 ANK 4 ANK 5 ANK 6 Death GRR Nuclear localization si...

    gene.name: nfkb2
  7. NFKB2_CHICK UniProt:Swiss-Prot

    ID: P98150

    Description: Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p52 subunit RHD ANK 1 ANK 2 ANK 3 ANK 4 ANK 5 ANK 6 Death GRR Nuclear localization si...

    gene.name: NFKB2
  8. NFKB2_MOUSE UniProt:Swiss-Prot

    ID: Q9WTK5

    Description: Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p52 subunit RHD ANK 1 ANK 2 ANK 3 ANK 4 ANK 5 ANK 6 ANK 7 Death GRR Nuclear localizat...

    gene.name: Nfkb2
  9. RNA-seq data from murine eGFP+ relbfl/flnfkb2fl/flCg1-Cre and Cg1-Cre splenic germinal center B cells purified by fluorescent activated cell sorting ArrayExpress

    ID: E-GEOD-77374

    Description: RNA-seq analysis of murine eGFP+ relbfl/flnfkb2fl/flCg1-Cre and Cg1-Cre splenic germinal center B cells identifies genes regulated by the transcriptio...

  10. X-ray structure of a NF-kB p52/RelB/DNA complex PDB

    ID: PDB:3DO7

    Description: PROTEIN/DNA Complex

    gene.name: NFKB2, LYT10
  11. Solution structure of the Death domain of Nuclear factor NF-kappa-B p100 PDB

    ID: PDB:2D96

    Description: Nuclear factor NF-kappa-B p100 subunit

    gene.name: NFKB2
  12. Transcription profiling by array of primary juvenile human dermal fiborblasts with or without single/double siRNA knock-down of transcription factors ... ArrayExpress

    ID: E-MTAB-1593

    Description: The NF-kappaB and p53 transcription factors control the expression of complex gene regulatory networks in response to many cell stresses and stimuli. ...

  13. RNA-seq data from murine eGFP+ relbfl/flnfkb2fl/flCg1-Cre and Cg1-Cre splenic germinal center B cells purified by fluorescent activated cell sorting. BioProject

    ID: PRJNA310183

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. RAG-mediated DNA double strand breaks activate a cell-type-specific checkpoint to inhibit pre-B cell receptor signals OmicsDI

    ID: E-GEOD-67854

    Date Released: 01-15-2016

    Description: (Rag1-/-:μIgH:Bcl2, Art-/-:μIgH:Bcl2 and Art-/-:Nfkb2-/-:μIgH:Bcl2) were withdrawn from IL-7 for 2 days. RNA was isolated using RNeasy (Qiagen). Gene expression profiling was performed using Illumina MouseRef-8 expression microarrays....

  15. RNAseq data from in vitro-stimulated (6 hours) murine nfkb2fl/flCD19-Cre and CD19-Cre splenic B cells purified by magnetic cell separation (CD40) BioProject

    ID: PRJNA305288

    Keywords: Transcriptome or Gene expression

    Access Type: download

  16. RNAseq data from in vitro-stimulated (6 hours) murine nfkb2fl/flCD19-Cre and CD19-Cre splenic B cells purified by magnetic cell separation (BAFF) BioProject

    ID: PRJNA305289

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. Gene expression profile of the NF-κB subunit p52 in Hodgkin’s lymphoma BioProject

    ID: PRJNA270498

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: -1236 cells. Two distinct siRNA sequences against NFKB2 and two non-targeting siRNA sequences (control) were used. Experiments were performed in biological triplicates....
  18. Comparison of RelB-/- and RelB+/- thymi ArrayExpress

    ID: E-GEOD-43154

    Description: Thymic medullary epithelial cell (mTEC) expression of the autoimmune regulator AIRE, and of tissue-specific antigens, is controlled by members of the ...

  19. RAG-mediated DNA double strand breaks activate a cell-type-specific checkpoint to inhibit pre-B cell receptor signals ArrayExpress

    ID: E-GEOD-67854

    Description: (Rag1-/-:μIgH:Bcl2, Art-/-:μIgH:Bcl2 and Art-/-:Nfkb2-/-:μIgH:Bcl2) were withdrawn from IL-7 for 2 days. RNA was isolated using RNeasy (Qiagen). Gene expression profiling was performed using Illumina MouseRef-8 expression microarrays....

  20. Comparison of RelB-/- and RelB+/- thymi BioProject

    ID: PRJNA184731

    Keywords: Transcriptome or Gene expression

    Access Type: download


Displaying 20 of 40 results for "NFKB2"