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Displaying 19 of 19 results for "NDNF"
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  1. NDNF_XENLA UniProt:Swiss-Prot

    ID: Q6GNK9

    Description: Protein NDNF Fibronectin type-III 1 Fibronectin type-III 2 Poly-Ser N-linked (GlcNAc...)

  2. Proneurogenic ligands defined by modeling developing cortex growth factor communication networks BioProject

    ID: PRJNA329432

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Proneurogenic ligands defined by modeling developing cortex growth factor communication networks ArrayExpress

    ID: E-GEOD-84482

    Description: a. The resultant model predicts a complex growth factor environment with multiple autocrine and paracrine interactions. We tested this communication model, focusing on neurogenesis, and identified IFNγ, Nrtn and glial-derived neurotrophic factor (GDNF) as ligands with unexpected roles in promoting neurogenic differentiation of NPCs in vivo. We prepared E16 cortical neuron, E13 cortical precursor and co-cultured E16 cortical neuron and E13 cortical precursor cultures from three independent biological replicates....

  4. Mus musculus : Glial cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence BioProject

    ID: PRJNA314493

    Keywords: metagenome

    Access Type: download

  5. ChIP-on-Chip for the Ciliary derived stem/progenitor cells and their differentiated progeny ArrayExpress

    ID: E-GEOD-65268

    Description: ion (H3K4me3, H3K27me3 and RNA Pol II) in Ciliary derived stem/progenitor cells and differentiated cells. In the present study we focus on the cellular differentiation that involves loss of pluripotency and gain of lineage ...

  6. ChIP-on-Chip for the Ciliary derived stem/progenitor cells and their differentiated progeny. BioProject

    ID: PRJNA273564

    Keywords: Epigenomics

    Access Type: download

  7. Transcription profiling of mouse Bax null versus NGF-Bax double null animals ArrayExpress

    ID: E-GEOD-10498

    Description: d mediated by a series of feedback loops. Target-derived nerve growth factor (NGF) promoted expression of its receptor TrkA in neurons and prolonged TrkA-mediated signals. NGF also controlled expression of brain derived neurotrophic factor (BDNF) and neurotrophin-4 (NT...

  8. Proneurogenic ligands defined by modeling developing cortex growth factor communication networks OmicsDI

    ID: E-GEOD-84482

    Date Released: 08-23-2016

    Description: a. The resultant model predicts a complex growth factor environment with multiple autocrine and paracrine interactions. We tested this communication model, focusing on neurogenesis, and identified IFNγ, Nrtn and glial-derived neurotrophic factor (GDNF) as ligands with unexpected roles in promoting neurogenic differentiation of NPCs in vivo. We prepared E16 cortical neuron, E13 cortical precursor and co-cultured E16 cortical neuron and E13 cortical precursor cultures from three independent biological replicates....

  9. ChIP-on-Chip for the Ciliary derived stem/progenitor cells and their differentiated progeny. OmicsDI

    ID: E-GEOD-65268

    Date Released: 01-09-2016

    Description: ion (H3K4me3, H3K27me3 and RNA Pol II) in Ciliary derived stem/progenitor cells and differentiated cells. In the present study we focus on the cellular differentiation that involves loss of pluripotency and gain of lineage ...

  10. Comparison of SCG expression profiles from Bax null versus NGF-Bax double null mice BioProject

    ID: PRJNA107953

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: d mediated by a series of feedback loops. Target-derived nerve growth factor (NGF) promoted expression of its receptor TrkA in neurons and prolonged TrkA-mediated signals. NGF also controlled expression of brain derived neurotrophic factor (BDNF) and neurotrophin-4 (NT...
  11. Transcription profiling by array of human SK-N-AS neuroblastoma cells treated with constructs expressing truncated or full-length NRSF ArrayExpress

    ID: E-GEOD-22467

    Description: Neuron-restrictive silencer factor (NRSF) and its isoforms are differentially regulated in rodent models of sel...

  12. microRNA-125b Promotes Neuronal Differentiation in Human Cells by Repressing Multiple Targets BioProject

    ID: PRJNA112219

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: on induced by all-trans¬-retinoic acid and brain-derived neurotrophic factor. We demonstrated that ectopic expression of either miR-124a or miR-125b increases the percentage of differentiated SH-SY5Y cells with neurite outgrowth. Subsequently, we focused our functional analysis on miR-125b and demonstrated the important role of th...
  13. Impact of NRSF variant over-expression in SK-N-AS human neuroblastoma cells BioProject

    ID: PRJNA128615

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Neuron-restrictive silencer factor (NRSF) and its isoforms are differentially regulated in rodent models of sel...
  14. Transcription profiling by array of human SK-N-AS neuroblastoma cells treated with constructs expressing truncated or full-length NRSF OmicsDI

    ID: E-GEOD-22467

    Date Released: 05-01-2014

    Description: Neuron-restrictive silencer factor (NRSF) and its isoforms are differentially regulated in rodent models of sel...

  15. USSC secretome OmicsDI

    ID: PXD002241

    Date Released: 07-20-2015

    Description: factors like, e.g., neuronal growth regulator 1, NDNF, SPARC and PEDF spanning the whole abundance range of USSC secretome. By the means of primary cortical neurons in vitro assays we verified SPARC and PEDF as significantly involved in USSC mediated neurite growth and therewith underline their role in improved locomotor recovery after transplantation. From our data we are convinced that USSC are a valuable tool in regenerative medicine as USSC’s secretome contains a comprehensive network of trophic factors supporting nerve regeneration not only by a single process but also maintained its regenerative phenotype by a multitude of relevant biological processes....

  16. Identification of a neuronal gene expression signature: Role of cell-cycle arrest in murine neuronal differentiation in vitro ArrayExpress

    ID: E-GEOD-24116

    Description: dy of the C17.2 NSC line and primary neurons (PN) derived from embryonic mouse brains. Microarray analysis revealed a neuron-specific gene expression signature that distinguishes PN from NSCs, with elevated levels of transcripts involved in neuronal functions such as neurite development, axon guidance, in PN. The same comparison revealed decreased levels of multiple cytokine transcripts such as IFN, TNF, TGF, and IL. Among the differentially expressed genes, we found a statistically significant enrichment of genes in the ephrin, neurotrophin, CDK5 and actin pathways which cont...

  17. Methylphenidate exposure induces dopamine neuron loss and activation of microglia in the basal ganglia of mice ArrayExpress

    ID: E-GEOD-33619

    Description: served a significant reduction (~20%) in dopamine neuron numbers in the substantia nigra pars compacta (SNpc) following chronic administration of 10mg/kg MPH. This dosage of MPH also induced a significant increase in the number of morphologically-activated SNpc microglia. Additionally, exposure to either 1mg/kg or 10 mg/kg MPH increased the sensitivity of SNpc dopamine neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced oxidative stress. Unbiased gene screening employing Affymetrix GeneChip® HT MG-430 PM revealed changes in 115 and 54 genes in the substantia nigra (SN) of mice exposed to 1mg/kg and 10mg/kg MPH doses, respectively. Decreases in the mRNA levels of gdnf, dat1, vmat2 and th in the substantia ni...

  18. Methylphenidate exposure induces dopamine neuron loss and activation of microglia in the basal ganglia of mice BioProject

    ID: PRJNA148497

    Keywords: Transcriptome or Gene expression

    Access Type: download

  19. Identification of a neuronal gene expression signature: Role of cell-cycle arrest in murine neuronal differentiation in vitro BioProject

    ID: PRJNA130049

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: dy of the C17.2 NSC line and primary neurons (PN) derived from embryonic mouse brains. Microarray analysis revealed a neuron-specific gene expression signature that distinguishes PN from NSCs, with elevated levels of transcripts involved in neuronal functions such as neurite development, axon guidance, in PN. The same comparison revealed decreased levels of multiple cytokine transcripts such as IFN, TNF, TGF, and IL. Among the differentially expressed genes, we found a statistically significant enrichment of genes in the ephrin, neurotrophin, CDK5 and actin pathways which cont...

Displaying 19 of 19 results for "NDNF"