NDEL1 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 22 results for "NDEL1"
i
  1. COILED-COIL REGION OF NUDEL PDB

    ID: PDB:2V71

    Description: NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1

  2. CRYSTAL STRUCTURE OF THE COILED-COIL DOMAIN OF NDEL1 (A.A. 58 TO 169)C PDB

    ID: PDB:2V66

    Description: NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1

  3. LIS1_MACFA UniProt:Swiss-Prot

    ID: Q8HXX0

    Description: g factor acetylhydrolase IB subunit alpha LisH WD 1 WD 2 WD 3 WD 4 WD 5 WD 6 WD 7 Interaction with NDEL1 Interaction with NDE1 Required for self-association and interaction with PA...

  4. DISC1_RAT UniProt:Swiss-Prot

    ID: Q810H6

    Description: Disrupted in schizophrenia 1 homolog Interaction with MAP1A Interaction with TRAF3IP1 Required for localization to punctate cytoplasmic foci Necessary and suf...

  5. LIS1_FELCA UniProt:Swiss-Prot

    ID: B0LSW3

    Description: g factor acetylhydrolase IB subunit alpha LisH WD 1 WD 2 WD 3 WD 4 WD 5 WD 6 WD 7 Interaction with NDEL1 Interaction with NDE1 Required for self-association and interaction with PA...

  6. LIS1_BOVIN UniProt:Swiss-Prot

    ID: P43033

    Description: g factor acetylhydrolase IB subunit alpha LisH WD 1 WD 2 WD 3 WD 4 WD 5 WD 6 WD 7 Interaction with NDEL1 Interaction with NDE1 Required for self-association and interaction with PA...

  7. LIS1_PANTR UniProt:Swiss-Prot

    ID: Q5IS43

    Description: g factor acetylhydrolase IB subunit alpha LisH WD 1 WD 2 WD 3 WD 4 WD 5 WD 6 WD 7 Interaction with NDEL1 Interaction with NDE1 Required for self-association and interaction with PA...

  8. LIS1_PONAB UniProt:Swiss-Prot

    ID: Q5REG7

    Description: g factor acetylhydrolase IB subunit alpha LisH WD 1 WD 2 WD 3 WD 4 WD 5 WD 6 WD 7 Interaction with NDEL1 Interaction with NDE1 Required for self-association and interaction with PA...

  9. LIS1_PIG UniProt:Swiss-Prot

    ID: Q9GL51

    Description: g factor acetylhydrolase IB subunit alpha LisH WD 1 WD 2 WD 3 WD 4 WD 5 WD 6 WD 7 Interaction with NDEL1 Interaction with NDE1 Required for self-association and interaction with PA...

  10. KTNA1_MOUSE UniProt:Swiss-Prot

    ID: Q9WV86

    Description: ion with microtubules Interaction with dynein and NDEL1 Interaction with KATNB1 Phosphoserine; by DYRK2...

  11. KTNA1_MACFA UniProt:Swiss-Prot

    ID: Q4R407

    Description: ion with microtubules Interaction with dynein and NDEL1 Interaction with KATNB1 Phosphoserine; by DYRK2 Phosphoserine; by DYRK2 Phosphothreonine; by DYRK2 Phosphoserine...

  12. NDL1A_XENLA UniProt:Swiss-Prot

    ID: Q6DK98

    Description: Nuclear distribution protein nudE-like 1-A

  13. NDL1B_XENLA UniProt:Swiss-Prot

    ID: Q66IZ7

    Description: Nuclear distribution protein nudE-like 1-B

  14. Yeast response to the DNA damaging beta-lapachone ArrayExpress

    ID: E-GEOD-15412

    Description: eatment elicited similar ROS production in WT and nde2 cells, and dicoumarol did not affect cell viability in b-lap treated yeasts. Most interestingly, DNA damage responses triggered by b-lap were abolished in the nde2 mutant. Furthermore, the nde2 mutant was sensitive to DNA damaging agents other than b-lap. These data indicated that ROS production did not mediate b-lap cytotoxicity and highlighted a role of Nde2p in DNA damage checkpoints. Amino acid biosynthesis genes were also differentially expressed in b-lap treated cells, suggesting that b-lap exposure somehow triggered the General Control of Nutrients (GCN) pathway. Supporting this, b-lap treatment increased phosphorylation of eIF2 alpha in a Gcn2p-dependent manner. eIF2alpha phosphorylation required Gcn1p and Gcn20p and surprisingly Nde2p. Gcn2p was also shown to be required for the G1 checkpoint triggered by b-lap and for cell survival. Remarkably, b-lap treatment also increased phosphorylation of eIF2 alpha in breast tumour cells, which was partially dependent on the Nde...

  15. Yeast response to the DNA damaging beta-lapachone OmicsDI

    ID: E-GEOD-15412

    Date Released: 05-01-2014

    Description: eatment elicited similar ROS production in WT and nde2 cells, and dicoumarol did not affect cell viability in b-lap treated yeasts. Most interestingly, DNA damage responses triggered by b-lap were abolished in the nde2 mutant. Furthermore, the nde2 mutant was sensitive to DNA damaging agents other than b-lap. These data indicated that ROS production did not mediate b-lap cytotoxicity and highlighted a role of Nde2p in DNA damage checkpoints. Amino acid biosynthesis genes were also differentially expressed in b-lap treated cells, suggesting that b-lap exposure somehow triggered the General Control of Nutrients (GCN) pathway. Supporting this, b-lap treatment increased phosphorylation of eIF2 alpha in a Gcn2p-dependent manner. eIF2alpha phosphorylation required Gcn1p and Gcn20p and surprisingly Nde2p. Gcn2p was also shown to be required for the G1 checkpoint triggered by b-lap and for cell survival. Remarkably, b-lap treatment also increased phosphorylation of eIF2 alpha in breast tumour cells, which was partially dependent on the Nde...

  16. Yeast response to the DNA damaging beta-lapachone BioProject

    ID: PRJNA117087

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: eatment elicited similar ROS production in WT and nde2 cells, and dicoumarol did not affect cell viability in b-lap treated yeasts. Most interestingly, DNA damage responses triggered by b-lap were abolished in the nde2 mutant. Furthermore, the nde2 mutant was sensitive to DNA damaging agents other than b-lap. These data indicated that ROS production did not mediate b-lap cytotoxicity and highlighted a role of Nde2p in DNA damage checkpoints. Amino acid biosynthesis genes were also differentially expressed in b-lap treated cells, suggesting that b-lap exposure somehow triggered the General Control of Nutrients (GCN) pathway. Supporting this, b-lap treatment increased phosphorylation of eIF2 alpha in a Gcn2p-dependent manner. eIF2alpha phosphorylation required Gcn1p and Gcn20p and surprisingly Nde2p. Gcn2p was also shown to be required for the G1 checkpoint triggered by b-lap and for cell survival. Remarkably, b-lap treatment also increased phosphorylation of eIF2 alpha in breast tumour cells, which was partially dependent on the Nde...
  17. Additional file 5: Table S4. of VarElect: the phenotype-based variation prioritizer of the GeneCards Suite Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3601016_D4

    Release Date: 12-14-2016

    Description: Two vcf files produced from the exome sequencing of the Capillary Leak Syndrome clinical case described in the results section, consisting of the infl...

    dataset.creators: Nudel, Ron
  18. Additional file 7: Table S6. of VarElect: the phenotype-based variation prioritizer of the GeneCards Suite Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3601016_D1

    Release Date: 12-14-2016

    Description: Vcf file produced from the exome sequencing of the Arthrogryposis Multiplex Congenita clinical case described in the results section. (GZ 1665 kb)

    dataset.creators: Nudel, Ron
  19. Additional file 4: Table S3. of VarElect: the phenotype-based variation prioritizer of the GeneCards Suite Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3601016_D2

    Release Date: 12-14-2016

    Description: Vcf file produced from the exome sequencing of the Congenital Diarrhea clinical case described in the results section. (GZ 14654 kb)

    dataset.creators: Nudel, Ron
  20. Additional file 3: Table S2. of VarElect: the phenotype-based variation prioritizer of the GeneCards Suite Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3601016_D5

    Release Date: 12-14-2016

    Description: Gene lists and corresponding phenotypes for Phenomyzer and Exomiser benchmarking. (XLSX 16.0 kb)

    dataset.creators: Nudel, Ron

Displaying 20 of 22 results for "NDEL1"