MTA3 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 24 results for "MTA3"
i
  1. Profiling the target genes for LSD1, MTA1, MTA2, and MTA3 in MCF-7 BioProject

    ID: PRJNA111219

    Keywords: Epigenomics

    Access Type: download

  2. Profiling the target genes for LSD1, MTA1, MTA2, and MTA3 in MCF-7 ArrayExpress

    ID: E-GEOD-14260

    Description: he whole genome targets for LSD1, MTA1, MTA2, and MTA3 We analyzed arrays using antibodies against LSD1, MTA1, MTA2, or MTA3 and negative control to acquire the enriched ratio of each gene....

  3. Solution structure of the myb-like DNA-binding domain of mouse MTA3 protein PDB

    ID: PDB:2CRG

    Description: Metastasis associated protein MTA3

  4. MTA3_BOVIN UniProt:Swiss-Prot

    ID: A6QL72

    Description: Metastasis-associated protein MTA3 BAH ELM2 SANT GATA-type; atypical Phosphoserine Phosphothr...

  5. Profiling the target genes for LSD1, MTA1, MTA2, and MTA3 in MCF-7 OmicsDI

    ID: E-GEOD-14260

    Date Released: 05-04-2014

    Description: he whole genome targets for LSD1, MTA1, MTA2, and MTA3 We analyzed arrays using antibodies against LSD1, MTA1, MTA2, or MTA3 and negative control to acquire the enriched ratio of each gene....

  6. Homo sapiens : Homo sapiens Raw sequence reads BioProject

    ID: PRJNA278917

    Keywords: raw sequence reads

    Access Type: download

    dataset.description: nscription repression program composed of G9A and MTA3-, but not MTA1- or MTA2-, constituted NuRD complex. Genome-wide analysis of the GATA3/G9A/NuRD(MTA3) targets identified a cohort of genes that are critically involved in epithelial-to-mesenchymal transition and cell invasion....
  7. CHD5, A Brain-Specific Chromatin Remodeling Enzyme, Regulates Expression Of Neuronal Genes ArrayExpress

    ID: E-GEOD-27620

    Description: ssed. CHD5 protein isolated from mouse brain was associated with HDAC2, p66, MTA3 and RbAp46 in a megadalton complex. CHD5 protein was detected in several rat brain regions and appeared to be enriched in neurons. CHD5 protein was predominantly nuclear in primary rat neurons and brain sections. Microarray analysis revealed genes that were upregulated and downregulated when CHD5 was depleted from pr...

  8. ROLE OF HMGA2 IN THE EPITHELIAL TO MESENCHYMAL TRANSITION ASSOCIATED WITH ENDOMETRIAL CARCINOGENESIS ArrayExpress

    ID: E-GEOD-33723

    Description: ion between the expression of HMGA2 and let-7b, a member of the let-7 family of miRNAs that represses HMGA2 expression. These changes were also associated with overexpression of Lin28B, a suppressor of microRNA biogenesis implicated in cancer progression and metastasis. Finally, HMGA2 overexpression, which was detected in less than 3% of EECs, was observed in many non-endometrioid carcinomas (46%). For the first time, we describe a role for HMGA2 in both the process of EMT that contributes to endometrial carcinogenesis and in the acquisition of aggressive phenotypes by this neoplasia. Moreover, we demonstrate changes in the expression of genes modulating processes such as EMT, muscle differentiation, the expression of cancer testis antigens (CTAs) and the immune re...

  9. Synergism of calcium sensing receptor and vitamin D receptor mediated signaling in epidermal differentiation [double KO] ArrayExpress

    ID: E-GEOD-68725

    Description: odulating gene transcription, whereas the CaSR, a member of the family C G-protein coupled receptor, calcium mobilizes intracellular calcium and induces the formation of cell-cell junctions. 1,25D3 augments the sensitivity of the prodifferentiating actions of calcium by increasing the expression of CaSR. CaSR- and VDR-deficient keratinocytes share common characteristics such as abnormal intercellular adhesion and sphigolipid metabolism. Bo...

  10. Synergism of calcium sensing receptor and vitamin D receptor mediated signaling in epidermal differentiation [VDR KO] ArrayExpress

    ID: E-GEOD-68723

    Description: odulating gene transcription, whereas the CaSR, a member of the family C G-protein coupled receptor, calcium mobilizes intracellular calcium and induces the formation of cell-cell junctions. 1,25D3 augments the sensitivity of the prodifferentiating actions of calcium by increasing the expression of CaSR. CaSR- and VDR-deficient keratinocytes share common characteristics such as abnormal intercellular adhesion and sphigolipid metabolism. Bo...

  11. Synergism of calcium sensing receptor and vitamin D receptor mediated signaling in epidermal differentiation [CaSR KO] ArrayExpress

    ID: E-GEOD-68724

    Description: odulating gene transcription, whereas the CaSR, a member of the family C G-protein coupled receptor, calcium mobilizes intracellular calcium and induces the formation of cell-cell junctions. 1,25D3 augments the sensitivity of the prodifferentiating actions of calcium by increasing the expression of CaSR. CaSR- and VDR-deficient keratinocytes share common characteristics such as abnormal intercellular adhesion and sphigolipid metabolism. Bo...

  12. SIRT7 suppresses tumorigenesis by attenuating MYC activity ArrayExpress

    ID: E-GEOD-50076

    Description: SIRT7 is a member of the mammalian sirtuin family of NAD+ dependent deacylases, and interacts with RNA polymerase I and UB...

  13. CHD5, A Brain-Specific Chromatin Remodeling Enzyme, Regulates Expression Of Neuronal Genes. BioProject

    ID: PRJNA138245

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ssed. CHD5 protein isolated from mouse brain was associated with HDAC2, p66, MTA3 and RbAp46 in a megadalton complex. CHD5 protein was detected in several rat brain regions and appeared to be enriched in neurons. CHD5 protein was predominantly nuclear in primary rat neurons and brain sections. Microarray analysis revealed genes that were upregulated and downregulated when CHD5 was depleted from pr...
  14. K562 leukaemia cell line treated with thalidomide analog ArrayExpress

    ID: E-GEOD-14945

    Description: astoma. They are non-toxic to adult animals up-to 1 g/kg but are highly teratogenic to zebrafish embryos at micromolar concentrations resulting defects in developing muscle. The analogs resulted in calcium release from the endoplasmic reticulum (ER), induction of reactive oxygen species (ROS), ER stress and finally apoptosis. Gene expression analysis confirmed the induction of ER stress-mediated apoptosis pathway components, such as growth arrest- and DNA damage-inducible gene 153 (GADD153), ATF3, Luman/CREB3 recruitment factor (LRF) and the ER-associated degradation-related gene HERPUD1. Tumor suppressors, P53, LATS2 and ING3 were also up-regulated in various cell lines after drug treatment. Exogenous docosahexaenoic acid or ei...

  15. Influence of chitin on the transcriptome of Vibrio coralliilyticus S2052 and Photobacterium galatheae S2753 (P. galatheae) BioProject

    ID: PRJNA319974

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Members of the Vibrionaceae family are often found associated with chitin-containing organisms and they are thought to play a major role in ...
  16. Influence of chitin on the transcriptome of Vibrio coralliilyticus S2052 and Photobacterium galatheae S2753 (V. coralliilyticus) BioProject

    ID: PRJNA319975

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Members of the Vibrionaceae family are often found associated with chitin-containing organisms and they are thought to play a major role in ...
  17. K562 leukaemia cell line treated with thalidomide analog BioProject

    ID: PRJNA111991

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: astoma. They are non-toxic to adult animals up-to 1 g/kg but are highly teratogenic to zebrafish embryos at micromolar concentrations resulting defects in developing muscle. The analogs resulted in calcium release from the endoplasmic reticulum (ER), induction of reactive oxygen species (ROS), ER stress and finally apoptosis. Gene expression analysis confirmed the induction of ER stress-mediated apoptosis pathway components, such as growth arrest- and DNA damage-inducible gene 153 (GADD153), ATF3, Luman/CREB3 recruitment factor (LRF) and the ER-associated degradation-related gene HERPUD1. Tumor suppressors, P53, LATS2 and ING3 were also up-regulated in various cell lines after drug treatment. Exogenous docosahexaenoic acid or ei...
  18. Analysis of the CcpA regulon in Staphylococcus aureus ArrayExpress

    ID: E-GEOD-12614

    Description: ound The catabolite control protein A (CcpA) is a member of the LacI/GalR family of transcriptional regulators controlling carbon-metabolism pathways in low-GC Gram pos...

  19. Hepatic miRNA profiles and thyroid hormone homeostasis in rats exposed to dietary potassium perfluorooctanesulfonate (PFOS) [mRNA] ArrayExpress

    ID: E-GEOD-69520

    Description: gnificantly altered. Three members of the miR-200 family were the most increased, while miR-122 and miR-21 were the most decreased, in PFOS-treated relative to control rats. Expression of the miR-23b/27b/24 cluster also decreased in PFOS-treated animals. Pathway analysis of miRNAs and associated gene expression changes demonstrated enrichment of transcripts involved in epithelial to mesenchymal transition (EMT), which is a primary process involved in tumor cell motility and cancer metastasis. Liver expression analysis revealed transcripts that may mediate PFOS effects on thyroid hormone (TH) homeostasis including: activation of the CAR/PXR pathway, phase II/III enzymes, and deiodinase. These changes are consistent with low serum TH due to enhanced metabolic clearance of TH. However, most TH hepatic target genes were not altered in a manner consistent w...

  20. Analysis of the CcpA regulon in Staphylococcus aureus BioProject

    ID: PRJNA112883

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ound The catabolite control protein A (CcpA) is a member of the LacI/GalR family of transcriptional regulators controlling carbon-metabolism pathways in low-GC Gram pos...

Displaying 20 of 24 results for "MTA3"