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Displaying 20 of 20 results for "MMP26"
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  1. Solution Structure of Matrilysin (MMP-7) Complexed to Constraint Conformational Sulfonamide Inhibitor PDB

    ID: PDB:2DDY

    Description: Matrilysin (E.C.3.4.24.23)

  2. MATRILYSIN COMPLEXED WITH HYDROXAMATE INHIBITOR PDB

    ID: PDB:1MMQ

    Description: MATRILYSIN, N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10...

  3. MMP7_MOUSE UniProt:Swiss-Prot

    ID: Q10738

    Description: Activation peptide Matrilysin Cysteine switch Zinc 2; in inhibited form Calcium 1 Zinc 1 Zinc 1 Calcium 2 Calciu...

  4. MATRILYSIN COMPLEXED WITH SULFODIIMINE INHIBITOR PDB

    ID: PDB:1MMR

    Description: MATRILYSIN, 4-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.0(13,18)]NONADECA-12(19),13(18),15,17-TETRAENE-10-CARBAMOYL)PENTA-METHYLSUL...

  5. MMP7_RAT UniProt:Swiss-Prot

    ID: P50280

    Description: Activation peptide Matrilysin Cysteine switch Zinc 2; in inhibited form Calcium 1 Zinc 1 Zinc 1 Calcium 2 Calciu...

  6. MMP7_FELCA UniProt:Swiss-Prot

    ID: P55032

    Description: Activation peptide Matrilysin Cysteine switch Zinc 2; in inhibited form Calcium 1 Zinc 1 Zinc 1 Calcium 2 Calciu...

  7. Differential gene expression in adipose tissue from obese human subjects during weight loss and weight maintenance ArrayExpress

    ID: E-GEOD-35411

    Description: JAZF zinc finger 1 (JAZF1), associated with type 2 diabetes, were downregulated. We could also confirm the downregulation of candidates for obesity and related traits, such as tenomodulin (TNMD) and matrix metallopeptidase 9 (MMP9), with weight loss. The expression of other candidates, such as cell death-inducing DFFA-like effector A (CIDEA) and stearoyl-CoA desaturase (SCD) were upregulated during weight loss but returned to baseline levels during weight maintenance. Conclusion. Genes in the adipose tissue are differentially expressed during weight loss and weight maintenance after weight loss. Genes that show sustained regulation may be of potential interest as markers of the beneficial effects of weight loss whereas others seem to be primarily involved in the process of weight loss itself. Nine participants were prescribed a low calorie diet (LCD) containing 1200 kcal/day for approximately three months (101 ± 26 days). Following the weight reduction phase the participants attended a six month follow-up period (167 ±...

  8. NMR Solution Structure of the PRO Form of Human Matrilysin (proMMP-7) in Complex with Anionic Membrane PDB

    ID: PDB:2MZI

    Description: Matrilysin (E.C.3.4.24.23)

  9. NMR Solution Structure of the PRO Form of Human Matrilysin (proMMP-7) in Complex with Zwitterionic Membrane PDB

    ID: PDB:2MZH

    Description: Matrilysin (E.C.3.4.24.23)

  10. NMR Solution Structure of the PRO Form of Human Matrilysin (proMMP-7) PDB

    ID: PDB:2MZE

    Description: Matrilysin (E.C.3.4.24.23)

  11. Expression data from Pseudomonas aeruginosa exposed airway epithelium from C57Bl6 and MMP-7 and MMP-10 deficient mice. BioProject

    ID: PRJNA100703

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: epithelial transcriptional responses dependent on matrilysin (MMP-7) and stromelysin-2 (MMP-10), two matrix metalloproteinases induced by acute P. aeruginosa pulmonary infection. Extraction of Differential Gene Expression (EDGE) analysis of gene expression changes in P. aeruginosa infected organotypic tracheal epithelial cell cultures from wildtype, Mmp7-/-, and Mmp10-/- m...
  12. Transcription profiling of mouse C57Bl6 MMP-7 and MMP-10 deficient mice Pseudomonas aeruginosa exposed airway epithelium. OmicsDI

    ID: E-GEOD-7957

    Date Released: 03-27-2012

    Description: epithelial transcriptional responses dependent on matrilysin (MMP-7) and stromelysin-2 (MMP-10), two matrix metalloproteinases induced by acute P. aeruginosa pulmonary infection. Extraction of Differential Gene Expression (EDGE) analysis of gene expression changes in P. aeruginosa infected organotypic tracheal epithelial cell cultures from wildtype, Mmp7-/-, and Mmp10-/- m...

  13. Transcription profiling of mouse C57Bl6 MMP-7 and MMP-10 deficient mice Pseudomonas aeruginosa exposed airway epithelium ArrayExpress

    ID: E-GEOD-7957

    Description: epithelial transcriptional responses dependent on matrilysin (MMP-7) and stromelysin-2 (MMP-10), two matrix metalloproteinases induced by acute P. aeruginosa pulmonary infection. Extraction of Differential Gene Expression (EDGE) analysis of gene expression changes in P. aeruginosa infected organotypic tracheal epithelial cell cultures from wildtype, Mmp7-/-, and Mmp10-/- m...

  14. Differential gene expression in adipose tissue from obese human subjects during weight loss and weight maintenance BioProject

    ID: PRJNA152805

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: JAZF zinc finger 1 (JAZF1), associated with type 2 diabetes, were downregulated. We could also confirm the downregulation of candidates for obesity and related traits, such as tenomodulin (TNMD) and matrix metallopeptidase 9 (MMP9), with weight loss. The expression of other candidates, such as cell death-inducing DFFA-like effector A (CIDEA) and stearoyl-CoA desaturase (SCD) were upregulated during weight loss but returned to baseline levels during weight maintenance. Conclusion. Genes in the adipose tissue are differentially expressed during weight loss and weight maintenance after weight loss. Genes that show sustained regulation may be of potential interest as markers of the beneficial effects of weight loss whereas others seem to be primarily involved in the process of weight loss itself. Overall design: Nine participants were prescribed a low calorie diet (LCD) containing 1200 kcal/day for approximately three months (101 ± 26 days). Following the weight reduction phase the participants attended a six month follow-u...
  15. MATRILYSIN COMPLEXED WITH CARBOXYLATE INHIBITOR PDB

    ID: PDB:1MMP

    Description: GELATINASE A, 5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YLCARBAMOYL)-HEXANOIC ACID

  16. Expression data from Pseudomonas aeruginosa exposed airway epithelium from C57Bl6 and MMP-7 and MMP-10 deficient mice. GEMMA

    ID: 2290

    Keywords: functional genomics

    Description: epithelial transcriptional responses dependent on matrilysin (MMP-7) and stromelysin-2 (MMP-10), two matrix metalloproteinases induced by acute P. aeruginosa pulmonary infection. Extraction of Differential Gene Expression (EDGE) analysis of gene expression changes in P. aeruginosa infected organotypic tracheal epithelial cell cultures from wildtype, Mmp7-/-, and Mmp10-/- m...

  17. Differential gene expression in adipose tissue from obese human subjects during weight loss and weight maintenance OmicsDI

    ID: E-GEOD-35411

    Date Released: 02-14-2012

    Description: JAZF zinc finger 1 (JAZF1), associated with type 2 diabetes, were downregulated. We could also confirm the downregulation of candidates for obesity and related traits, such as tenomodulin (TNMD) and matrix metallopeptidase 9 (MMP9), with weight loss. The expression of other candidates, such as cell death-inducing DFFA-like effector A (CIDEA) and stearoyl-CoA desaturase (SCD) were upregulated during weight loss but returned to baseline levels during weight maintenance. Conclusion. Genes in the adipose tissue are differentially expressed during weight loss and weight maintenance after weight loss. Genes that show sustained regulation may be of potential interest as markers of the beneficial effects of weight loss whereas others seem to be primarily involved in the process of weight loss itself. Nine participants were prescribed a low calorie diet (LCD) containing 1200 kcal/day for approximately three months (101 ± 26 days). Following the weight reduction phase the participants attended a six month follow-up period (167 ±...

  18. THE DISCOVERY OF MMP7 INHIBITORS EXPLOITING A NOVEL SELECTIVITY TRIGGER PDB

    ID: PDB:2Y6D

    Description: MATRILYSIN (E.C.3.4.24.23)

  19. Fibrogenic and redox-related but not proinflammatory genes are upregulated in lewis rat model of chronic silicosis BioProject

    ID: PRJNA140375

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: 2, and CCL7), redox enzymes (superoxide dismutase-2 and arginase-1), and the enzymatic activities of matrix metalloproteinases 2 and 9 were upregulated in acute and chronic silicosis; however, proinflammatory cytokines were strongly upregulated only in acute silicosis. Thus, inflammatory cytokines are associated with acute but not chronic silicosis; however, genes regulating fibrosis, oxidative stress, and metalloproteases may contribute to both acute and chronic silicosis. Overall design: 3 rats were chronically exposed to silica by inhalation. Briefly, exposure chambers were maintained with an airflow rate of ~15 cfm and temperature range of 22–26°C. Animals were exposed to 6.2 mg/m3 aerosolized silica (Min-U-Sil 5; U.S. Silica, Mill Creek, OK) with an average particle size of 1.75 ± 0.05 mm (mass median aerodynamic diameter) 6 h/d, 5 d/wk (Monday–Friday) for 6 wk. 3 control animals received filtered air under similar inhalation conditions....
  20. THE DISCOVERY OF MMP7 INHIBITORS EXPLOITING A NOVEL SELECTIVITY TRIGGER PDB

    ID: PDB:2Y6C

    Description: MATRILYSIN (E.C.3.4.24.23)


Displaying 20 of 20 results for "MMP26"