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Displaying 20 of 77 results for "MLLT10"
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  1. The Leukemia-associated Mllt10/Af10- Dot1l, dedicated b-catenin coactivators essential for intestinal homeostasis BioProject

    ID: PRJNA126101

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. EZH2 mutations can be detected in 23% of PICALM-MLLT10 (CALM-AF10) positive acute leukemias ArrayExpress

    ID: E-GEOD-30599

    Description: gic malignancies, such as EZH2 (enhancer of zeste homolog 2). EZH2 mutations were recurrently observed in lymphomas and chronic myeloid malignancies, but data in acute leukemias are limited. We investigated 13 PICALM-

  3. The Leukemia-associated Mllt10/Af10- Dot1l, dedicated b-catenin coactivators essential for intestinal homeostasis ArrayExpress

    ID: E-GEOD-21367

    Description: pal Findings: Using proteomics, we identified the leukemia-associated Mllt10/Af10 and the methyltransferase Dot1l, as Tcf4/beta-catenin interactors in mouse small intestinal crypts. Mllt10/Af10-Dot1l, essential for transcription elongation, are recruited to Wnt target genes in a beta-catenin -dependent manner, resulting in H3K79 methylation over their coding regions in vivo in proliferative crypts of mouse small intestine, in colorectal cancer and Wnt-inducible HEK293T cells. Depletion of MLLT10/AF10 in colorectal cancer and Wnt-inducible HEK293T cells followed by expression array analysis identifies MLLT10/

  4. The Leukemia-associated Mllt10/Af10- Dot1l, dedicated b-catenin coactivators essential for intestinal homeostasis OmicsDI

    ID: E-GEOD-21367

    Date Released: 05-01-2014

    Description: pal Findings: Using proteomics, we identified the leukemia-associated Mllt10/Af10 and the methyltransferase Dot1l, as Tcf4/beta-catenin interactors in mouse small intestinal crypts. Mllt10/Af10-Dot1l, essential for transcription elongation, are recruited to Wnt target genes in a beta-catenin -dependent manner, resulting in H3K79 methylation over their coding regions in vivo in proliferative crypts of mouse small intestine, in colorectal cancer and Wnt-inducible HEK293T cells. Depletion of MLLT10/AF10 in colorectal cancer and Wnt-inducible HEK293T cells followed by expression array analysis identifies MLLT10/

  5. EZH2 mutations can be detected in 23% of PICALM-MLLT10 (CALM-AF10) positive acute leukemias OmicsDI

    ID: E-GEOD-30599

    Date Released: 12-07-2011

    Description: gic malignancies, such as EZH2 (enhancer of zeste homolog 2). EZH2 mutations were recurrently observed in lymphomas and chronic myeloid malignancies, but data in acute leukemias are limited. We investigated 13 PICALM-

  6. EZH2 mutations can be detected in 23% of PICALM-MLLT10 (CALM-AF10) positive acute leukemias BioProject

    ID: PRJNA144567

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. MLLT10 gene recombinations in pediatric T-Acute Lymphoblastic Leukemia BioProject

    ID: PRJNA183087

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Expression Profiling of a CALM/AF10 leukemia mouse model BioProject

    ID: PRJNA95819

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. AF10.txt Figshare

    ID: doi:10.6084/M9.FIGSHARE.3506372.V1

    Release Date: 08-02-2016

    Description: Additional File 10. Phylip file of the concatenated nucleotide dataset (9711 nt.)

  10. MLLT10 gene recombinations in pediatric T-Acute Lymphoblastic Leukemia OmicsDI

    ID: E-GEOD-42765

    Date Released: 06-02-2014

    Description: MLLT10, a 24 exons gene at 10p12, is known in leukemogenesis as partner of MLL or PICALM and recently NAP1L1. We identified HNRNPH1...

  11. MLLT10 gene recombinations in pediatric T-Acute Lymphoblastic Leukemia ArrayExpress

    ID: E-GEOD-42765

    Description: MLLT10, a 24 exons gene at 10p12, is known in leukemogenesis as partner of MLL or PICALM and recently NAP1L1. We identified HNRNPH1...

  12. Identification of a Potently Oncogenic CALM-AF10 Minimal-Fusion Mutant (miRNA) ArrayExpress

    ID: E-GEOD-27512

    Description: 11) p (13;q14) translocation, giving rise to CALM-AF10, is a recurring chromosomal translocation observed in several types of acute leukemias as well as in lymphoma. We have previously demon...

  13. Identification of a Potently Oncogenic CALM-AF10 Minimal-Fusion Mutant (miRNA) BioProject

    ID: PRJNA141867

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. Identification of a Potently Oncogenic CALM-AF10 Minimal-Fusion Mutant (mRNA) ArrayExpress

    ID: E-GEOD-27513

    Description: 11) p (13;q14) translocation, giving rise to CALM-AF10, is a recurring chromosomal translocation observed in several types of acute leukemias as well as in lymphoma. We have previously demon...

  15. Gene expression profiling of CA10 and NHD13 murine AML ArrayExpress

    ID: E-GEOD-40531

    Description: issues in two different mouse models of AML, CALM-AF10 and NHD13, to clincally healthy transgenic and wildtype hematopoetic tissue to identify genes and pathways that can collaborate with these oncogenic fusion proteins to promote leukemic ...

  16. Microarray data of mouse MLL-AF10 leukemia cells with or without IKK inhibitor treatment BioProject

    ID: PRJNA198509

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. Identification of a Potently Oncogenic CALM-AF10 Minimal-Fusion Mutant (mRNA) BioProject

    ID: PRJNA141749

    Keywords: Transcriptome or Gene expression

    Access Type: download

  18. Crystal structure of PZP domain of human AF10 protein PDB

    ID: PDB:5DAG

    Description: Protein AF-10

  19. Microarray data of mouse MLL-AF10 leukemia cells with or without IKK inhibitor treatment ArrayExpress

    ID: E-GEOD-46250

    Description: MLL fusion proteins in leukemia induce aberrant transcriptional elongation and associated chromatin perturbations, however the upstream signaling pathways...

  20. Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide PDB

    ID: PDB:5DAH

    Description: Protein AF-10, Histone H3 peptide


Displaying 20 of 77 results for "MLLT10"