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Displaying 20 of 29 results for "MLKL"
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  1. Solution structure of the MLKL N-terminal domain PDB

    ID: PDB:2MSV

    Description: Mixed lineage kinase domain-like protein

  2. Crystal structure of the human MLKL kinase-like domain PDB

    ID: PDB:4M67

    Description: Mixed lineage kinase domain-like protein

  3. Crystal structure of the mouse RIP3-MLKL complex PDB

    ID: PDB:4M69

    Description: Receptor-interacting serine/threonine-protein kinase 3 (E.C.2.7.11.1), Mixed lineage kinase domain-

  4. Pseudokinase Domain of MLKL bound to Compound 4. PDB

    ID: PDB:5KO1

    Description: Mixed lineage kinase domain-like protein

  5. Crystal structure of the human MLKL pseudokinase domain PDB

    ID: PDB:4MWI

    Description: Mixed lineage kinase domain-like protein

  6. Crystal structure of the mouse MLKL kinase-like domain PDB

    ID: PDB:4M68

    Description: Mixed lineage kinase domain-like protein

  7. Structure of MLKL PDB

    ID: PDB:4BTF

    Description: MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN

  8. Pseudokinase Domain of MLKL bound to Compound 1. PDB

    ID: PDB:5KNJ

    Description: Pseudokinase Domain of human MLKL

  9. Synthetic cystine addiction via programmed necrosis in VHL-deficient renal cell carcinoma ArrayExpress

    ID: E-GEOD-60422

    Description: on of the Src-p38-Noxa signaling and TNFα-RIP1/3-MLKL necrosis pathways that culminate in MLKL oligomerization and programmed necrosis. Together, our data reveal that the contextual cystine-addictions in VHL-deficient ccRCC is dependent on activating pre-existing oncogenic pathways to trigger programmed necrosis. RNA was extracted by RNAeasy kits (Qiagen) from the RCC4 Vec and VHL-reconstituted cells which were exposed to the control full DMEM or cystine deprived DMEM media for 6 hours (three replicates in each condition)....

  10. Synthetic cystine addiction via programmed necrosis in VHL-deficient renal cell carcinoma OmicsDI

    ID: E-GEOD-60422

    Date Released: 07-11-2016

    Description: on of the Src-p38-Noxa signaling and TNFα-RIP1/3-MLKL necrosis pathways that culminate in MLKL oligomerization and programmed necrosis. Together, our data reveal that the contextual cystine-addictions in VHL-deficient ccRCC is dependent on activating pre-existing oncogenic pathways to trigger programmed necrosis. RNA was extracted by RNAeasy kits (Qiagen) from the RCC4 Vec and VHL-reconstituted cells which were exposed to the control full DMEM or cystine deprived DMEM media for 6 hours (three replicates in each condition)....

  11. Synthetic cystine addiction via programmed necrosis in VHL-deficient renal cell carcinoma BioProject

    ID: PRJNA258218

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: on of the Src-p38-Noxa signaling and TNFα-RIP1/3-MLKL necrosis pathways that culminate in MLKL oligomerization and programmed necrosis. Together, our data reveal that the contextual cystine-addictions in VHL-deficient ccRCC is dependent on activating pre-existing oncogenic pathways to trigger programmed necrosis. Overall design: RNA was extracted by RNAeasy kits (Qiagen) from the RCC4 Vec and VHL-reconstituted cells which were exposed to the control full DMEM or cystine deprived DMEM media for 6 hours (three replicates in each condition)....
  12. OTSSP167 KiNativ -- single dose experiment LINCS

    Data Type: Binding Protein binding profile

    Assay: KiNativ kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1188

    protein.name: MLKL
  13. QL-X-138 KiNativ -- single dose experiment LINCS

    Data Type: Binding Protein binding profile

    Assay: KiNativ kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1185

    protein.name: MLKL
  14. NVP-BHG712 KiNativ -- multiple dose experiment LINCS

    Data Type: Binding Protein binding profile

    Assay: KiNativ kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1090

    protein.name: MLKL
  15. GW-5074 KiNativ -- dose response experiment LINCS

    Data Type: Binding Protein binding profile

    Assay: KiNativ kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1074

    protein.name: MLKL
  16. CH5424802 KiNativ -- single dose experiment LINCS

    Data Type: Binding Protein binding profile

    Assay: KiNativ kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1091

    protein.name: MLKL
  17. 5z-7-oxozeaenol KiNativ -- single dose experiment LINCS

    Data Type: Binding Protein binding profile

    Assay: KiNativ kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1260

    protein.name: MLKL
  18. SB590885 KiNativ -- dose response experiment LINCS

    Data Type: Binding Protein binding profile

    Assay: KiNativ kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1075

    protein.name: MLKL
  19. QL-XII-47 KiNativ -- single dose experiment LINCS

    Data Type: Binding Protein binding profile

    Assay: KiNativ kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1349

    protein.name: MLKL
  20. Torin2 KiNativ -- single dose experiment LINCS

    Data Type: Binding Protein binding profile

    Assay: KiNativ kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1081

    protein.name: MLKL

Displaying 20 of 29 results for "MLKL"