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Displaying 20 of 20 results for "MIR193B"
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  1. Mus musculus : STAT5-regulated microRNA-193b controls hematopoietic stem and progenitor cell expansion by modulating cytokine receptor signaling BioProject

    ID: PRJNA267041

    Keywords: transcriptome

    Access Type: download

  2. miR-193b represses cell proliferation and regulates cyclin D1 in melanoma: benign nevi and metastatic melanoma ArrayExpress

    ID: E-GEOD-18509

    Description: re differentially expressed in melanoma. Notably, miR-193b was significantly down-regulated in the melanoma tissue examined. Using functional studies we demonstrated that over-expression of miR-193b significantly reduced melanoma cell proliferation, and arrested cell at G1 phase. Further gene expression analysis revealed that miR-193b regulated targets involved in cell cycle. Cyclin D1 was down-regulated by miR-193b at both the mRNA and protein level. This is the first study to show that the miR

  3. miR-193b represses cell proliferation and regulates cyclin D1 in melanoma: benign nevi and metastatic melanoma BioProject

    ID: PRJNA123265

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. miR-193b represses cell proliferation and regulates cyclin D1 in melanoma: benign nevi and metastatic melanoma OmicsDI

    ID: E-GEOD-18509

    Date Released: 06-10-2011

    Description: re differentially expressed in melanoma. Notably, miR-193b was significantly down-regulated in the melanoma tissue examined. Using functional studies we demonstrated that over-expression of miR-193b significantly reduced melanoma cell proliferation, and arrested cell at G1 phase. Further gene expression analysis revealed that miR-193b regulated targets involved in cell cycle. Cyclin D1 was down-regulated by miR-193b at both the mRNA and protein level. This is the first study to show that the miR

  5. MiR-193b promotes autophagy and non-apoptotic cell death in oesophageal cancer cells BioProject

    ID: PRJNA309528

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. MicroRNA-expression in tonsillar and base of tongue cancer related to HPV and clinical outcome BioProject

    ID: PRJNA323918

    Keywords: Other

    Access Type: download

  7. miRNA expression profiles in the serum of diabetic cats ArrayExpress

    ID: E-GEOD-37177

    Description: roRNAs are detectable in feline serum and whether microRNA expression profiles differ between healthy and diabetic cats. METHODS: Total RNA was extracted from 400 µl serum of healthy lean (HL) and newly diagnosed diabetic (D) cats. MicroRNA microarrays representing 1079 distinct mouse miRNA targets were used to measure miRNA expression in samples from eight HL and eight D cats. RESULTS: By microarray, 227 distinct microRNAs wer...

  8. MIRnome Profiling of Hereditary Pheochromocytoma and Paraganglioma Reveals Specific Signatures According to Primary Mutation: Possible Implications in... OmicsDI

    ID: E-GEOD-29742

    Date Released: 06-02-2014

    Description: nd progression of PCC/PGL, as well as to identify microRNA biomarkers specifically related to different PCC/PGL genetic classes known so far, we characterized microRNA profiles in a large series of frozen tumors with germline mutations in SDHD, SDHB, VHL, RET, NF1, and TMEM127 genes through microarray analysis. We identified microRNA signatures specific to, as well as common among, the genetic classes of PCC/PGLs, and the best candidate microRNAs (miR-122, miR-126*, miR-129*, miR-133b, miR-137, miR-183, miR-2...

  9. miRNA expression profiles in the serum of diabetic cats BioProject

    ID: PRJNA159203

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: roRNAs are detectable in feline serum and whether microRNA expression profiles differ between healthy and diabetic cats. METHODS: Total RNA was extracted from 400 µl serum of healthy lean (HL) and newly diagnosed diabetic (D) cats. MicroRNA microarrays representing 1079 distinct mouse miRNA targets were used to measure miRNA expression in samples from eight HL and eight D cats. RESULTS: By microarray, 227 distinct microRNAs wer...
  10. miRNA expression profiles in the serum of diabetic cats OmicsDI

    ID: E-GEOD-37177

    Date Released: 04-22-2013

    Description: roRNAs are detectable in feline serum and whether microRNA expression profiles differ between healthy and diabetic cats. METHODS: Total RNA was extracted from 400 µl serum of healthy lean (HL) and newly diagnosed diabetic (D) cats. MicroRNA microarrays representing 1079 distinct mouse miRNA targets were used to measure miRNA expression in samples from eight HL and eight D cats. RESULTS: By microarray, 227 distinct microRNAs wer...

  11. MIRnome Profiling of Hereditary Pheochromocytoma and Paraganglioma Reveals Specific Signatures According to Primary Mutation: Possible Implications in... ArrayExpress

    ID: E-GEOD-29742

    Description: nd progression of PCC/PGL, as well as to identify microRNA biomarkers specifically related to different PCC/PGL genetic classes known so far, we characterized microRNA profiles in a large series of frozen tumors with germline mutations in SDHD, SDHB, VHL, RET, NF1, and TMEM127 genes through microarray analysis. We identified microRNA signatures specific to, as well as common among, the genetic classes of PCC/PGLs, and the best candidate microRNAs (miR-122, miR-126*, miR-129*, miR-133b, miR-137, miR-183, miR-2...

  12. MIRnome Profiling of Hereditary Pheochromocytoma and Paraganglioma Reveals Specific Signatures According to Primary Mutation: Possible Implications in... BioProject

    ID: PRJNA141171

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: nd progression of PCC/PGL, as well as to identify microRNA biomarkers specifically related to different PCC/PGL genetic classes known so far, we characterized microRNA profiles in a large series of frozen tumors with germline mutations in SDHD, SDHB, VHL, RET, NF1, and TMEM127 genes through microarray analysis. We identified microRNA signatures specific to, as well as common among, the genetic classes of PCC/PGLs, and the best candidate microRNAs (miR-122, miR-126*, miR-129*, miR-133b, miR-137, miR-183, miR-2...
  13. MicroRNA profiling by array of 217 cases of chronic lymphocytic leukemia (CLL) comparing CLL-affected B-cells against normal B-cell... OmicsDI

    ID: E-MTAB-1454

    Date Released: 05-03-2014

    Description: rentially expressed miRNAs in CLL, which included miR-193b, miR-33b*, miR-365, miR-181b and miR-196a/b among the down-regulated and miR-23a/b, miR-26a, miR-130a, miR-532 (5p and 3p) among the up-regulated miRNAs. We also investigated differences of miRNA expression related to the IGHV somatic mutation status and to deletions at 13q, 11q and 17p or trisomy 12. Little differences were detected between unmutated (UM) versus mutated (M) CLLs, although miR-29c, miR-29c* and miR-146b were st...

  14. MicroRNA profiling by array of 217 cases of chronic lymphocytic leukemia (CLL) comparing CLL-affected B-cells against normal B-cell... ArrayExpress

    ID: E-MTAB-1454

    Description: rentially expressed miRNAs in CLL, which included miR-193b, miR-33b*, miR-365, miR-181b and miR-196a/b among the down-regulated and miR-23a/b, miR-26a, miR-130a, miR-532 (5p and 3p) among the up-regulated miRNAs. We also investigated differences of miRNA expression related to the IGHV somatic mutation status and to deletions at 13q, 11q and 17p or trisomy 12. Little differences were detected between unmutated (UM) versus mutated (M) CLLs, although miR-29c, miR-29c* and miR-146b were st...

  15. microRNA profiling of follicular lymphoma cells ArrayExpress

    ID: E-GEOD-28090

    Description: cular hits are required. We explored the role of microRNA (miRNA or miR) in the biology of FL by generating miRNA profiles of enriched sorted grade 1 and 2 FL tumor cells derived from 18 patients compared with enriched germinal center B-cells derived from seven follicular hyperplasia (FH). Expression levels of 851 human miRs were assayed and 133 miRs were sign...

  16. microRNA profiling of follicular lymphoma cells OmicsDI

    ID: E-GEOD-28090

    Date Released: 05-02-2014

    Description: cular hits are required. We explored the role of microRNA (miRNA or miR) in the biology of FL by generating miRNA profiles of enriched sorted grade 1 and 2 FL tumor cells derived from 18 patients compared with enriched germinal center B-cells derived from seven follicular hyperplasia (FH). Expression levels of 851 human miRs were assayed and 133 miRs were sign...

  17. Ethanol alters microNA expression in zebrafish embryos ArrayExpress

    ID: E-GEOD-32632

    Description: ) from 4 hours post-fertilization (hpf) to 24hpf. MicroRNA expression profiles revealed that ethanol exposure induces deregulation of miRNA expression significantly. Seven miRNAs are commonly up-regulated after both ethanol treatments, namely miR-153a, miR-725, miR-30d, let-7k, miR-100, miR-738 and miR-732, whereas downregulation of miR-23a, miR-203, let-7c, miR-128 and miR-193b is detected after 1% ethanol exposure only. Target prediction of deregulated miRNAs shows that putative targets are involved in cell cycle control, apoptosis and transcription, which are the main processes affected by ethanol toxicity. The overall study shows that the effects of ethanol on miRNA deregulation are dose-dependent and that miRNAs are relevant in the context of alcohol toxicity. Moreover, a miRNA toxicity signatur...

  18. microRNA profiling of follicular lymphoma cells BioProject

    ID: PRJNA139745

    Keywords: Transcriptome or Gene expression

    Access Type: download

  19. Ethanol alters microNA expression in zebrafish embryos OmicsDI

    ID: E-GEOD-32632

    Date Released: 06-26-2012

    Description: ) from 4 hours post-fertilization (hpf) to 24hpf. MicroRNA expression profiles revealed that ethanol exposure induces deregulation of miRNA expression significantly. Seven miRNAs are commonly up-regulated after both ethanol treatments, namely miR-153a, miR-725, miR-30d, let-7k, miR-100, miR-738 and miR-732, whereas downregulation of miR-23a, miR-203, let-7c, miR-128 and miR-193b is detected after 1% ethanol exposure only. Target prediction of deregulated miRNAs shows that putative targets are involved in cell cycle control, apoptosis and transcription, which are the main processes affected by ethanol toxicity. The overall study shows that the effects of ethanol on miRNA deregulation are dose-dependent and that miRNAs are relevant in the context of alcohol toxicity. Moreover, a miRNA toxicity signatur...

  20. Ethanol alters microNA expression in zebrafish embryos BioProject

    ID: PRJNA146975

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ) from 4 hours post-fertilization (hpf) to 24hpf. MicroRNA expression profiles revealed that ethanol exposure induces deregulation of miRNA expression significantly. Seven miRNAs are commonly up-regulated after both ethanol treatments, namely miR-153a, miR-725, miR-30d, let-7k, miR-100, miR-738 and miR-732, whereas downregulation of miR-23a, miR-203, let-7c, miR-128 and miR-193b is detected after 1% ethanol exposure only. Target prediction of deregulated miRNAs shows that putative targets are involved in cell cycle control, apoptosis and transcription, which are the main processes affected by ethanol toxicity. The overall study shows that the effects of ethanol on miRNA deregulation are dose-dependent and that miRNAs are relevant in the context of alcohol toxicity. Moreover, a miRNA toxicity signatur...

Displaying 20 of 20 results for "MIR193B"