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Displaying 20 of 237 results for "MELK"
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  1. MELK-T1, a small molecule inhibitor of protein kinase MELK, decreases DNA damage tolerance in highly proliferating cancer cells BioProject

    ID: PRJNA264218

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Glioma stem cell treatment with MELK-signaling inhibitors BioProject

    ID: PRJNA217324

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Human TNBC Cells 72h Treatment with 45nM OTSSP167 MELK Inhibitor vs. DMSO Control (SUM159) BioProject

    ID: PRJNA290119

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. Human TNBC Cells 48h Treatment with OTSSP167 MELK Inhibitor vs. DMSO Control BioProject

    ID: PRJNA283301

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Human TNBC Cells 72h Treatment with 45nM OTSSP167 MELK Inhibitor vs. DMSO Control BioProject

    ID: PRJNA283401

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Human TNBC Cells 72h Treatment with 4.5nM OTSSP167 MELK Inhibitor vs. DMSO Control BioProject

    ID: PRJNA283402

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Human TNBC Cells 72h Treatment with 4.5nM OTSSP167 MELK Inhibitor vs. DMSO Control (SUM159) BioProject

    ID: PRJNA290120

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. MELK and UBE2C gene knockdown in prostate cancer cell line PC3 BioProject

    ID: PRJNA146599

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. Glioma stem cell treatment with MELK-signaling inhibitors OmicsDI

    ID: E-GEOD-50227

    Date Released: 06-03-2014

    Description: kinase, maternal embryonic leucine-zipper kinase (MELK), is highly expressed in GBM tissues, specifically in GSCs, and its expression is inversely correlated with the post-surgical survival period of GBM patients. In addition, patient-derived GSCs depend on MELK for their survival and growth both in vitro and in vivo. Here, we provide evidence that the kinase activity of MELK is essential for the action of MELK in GSCs and vital for GBM growth. We utilized in silico structure-based analysis for protein-compound interaction to predict that a r...

  10. Human TNBC Cells 48h Treatment with OTSSP167 MELK Inhibitor vs. DMSO Control ArrayExpress

    ID: E-GEOD-68652

    Description: ing TNBC cells treated for 48 hours with OTSSp167 MELK Inhibitor and control (DMSO) Two-condition arrays: MDA-MB-231 cells were treated with either 4.5nM OTSSP167 MELK Inhibitor o...

  11. MPIP2_RAT UniProt:Swiss-Prot

    ID: P48966

    Description: atase 2 Rhodanese Phosphoserine Phosphoserine; by MELK Phosphoserine Phosphoserine; by MAPKAPK2 and MELK Phosphoserine; by MELK and MAPK14 Phosphoserine; by AURKA Ph...

  12. Glioma stem cell treatment with MELK-signaling inhibitors ArrayExpress

    ID: E-GEOD-50227

    Description: kinase, maternal embryonic leucine-zipper kinase (MELK), is highly expressed in GBM tissues, specifically in GSCs, and its expression is inversely correlated with the post-surgical survival period of GBM patients. In addition, patient-derived GSCs depend on MELK for their survival and growth both in vitro and in vivo. Here, we provide evidence that the kinase activity of MELK is essential for the action of MELK in GSCs and vital for GBM growth. We utilized in silico structure-based analysis for protein-compound interaction to predict that a r...

  13. Human TNBC Cells 72h Treatment with 45nM OTSSP167 MELK Inhibitor vs. DMSO Control ArrayExpress

    ID: E-GEOD-68692

    Description: ing TNBC cells treated for 72 hours with OTSSP167 MELK Inhibitor and control (DMSO) Two-condition arrays: MDA-MB-231 cells were treated with either 45nM OTSSP167 MELK Inhibitor or...

  14. Human TNBC Cells 72h Treatment with 4.5nM OTSSP167 MELK Inhibitor vs. DMSO Control (SUM159) ArrayExpress

    ID: E-GEOD-71026

    Description: ing TNBC cells treated for 72 hours with OTSSP167 MELK Inhibitor and control (DMSO) Two-condition arrays: SUM159 cells were treated with either 4.5nM OTSSP167 MELK Inhibitor or 0....

  15. Human TNBC Cells 72h Treatment with 45nM OTSSP167 MELK Inhibitor vs. DMSO Control (SUM159) ArrayExpress

    ID: E-GEOD-71027

    Description: ing TNBC cells treated for 72 hours with OTSSP167 MELK Inhibitor and control (DMSO) Two-condition arrays: SUM159 cells were treated with either 45nM OTSSP167 MELK Inhibitor or 0.0...

  16. MELK and UBE2C gene knockdown in prostate cancer cell line PC3 ArrayExpress

    ID: E-GEOD-32873

    Description: In order to address the putative role of MELK and UBE2C in prostate cancer development and progression, we performed functional analysis upon siRNA-based knockdown, and sea...

  17. MELK Leucine Zipper Kinase is a Key Differentiator between Glioblastoma Multiforme and Pilocytic Astrocytomas BioProject

    ID: PRJNA98051

    Keywords: Transcriptome or Gene expression

    Access Type: download

  18. Human TNBC Cells 72h Treatment with 4.5nM OTSSP167 MELK Inhibitor vs. DMSO Control ArrayExpress

    ID: E-GEOD-68691

    Description: ing TNBC cells treated for 72 hours with OTSSP167 MELK Inhibitor and control (DMSO) Two-condition arrays: MDA-MB-231 cells were treated with either 4.5nM OTSSP167 MELK Inhibitor o...

  19. of the maternal embryonic leucine zipper kinase (MELK) in triple-negative breast cancer cells indicate context-dependent effects and p53 as a key determinant... BioProject

    ID: PRJNA283397

    Access Type: download

  20. Crystal structure of unphosphorylated Maternal Embryonic Leucine zipper Kinase (MELK) in complex with a benzodipyrazole inhibitor PDB

    ID: PDB:4BKZ

    Description: MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE (E.C.2.7.11.1, 2.7.10.2)


Displaying 20 of 237 results for "MELK"