MEDAG | bioCADDIE Data Discovery Index
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Displaying 3 of 3 results for "MEDAG"
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  1. MEDAG_BOVIN UniProt:Swiss-Prot

    ID: A4IFN2

    Description: Mesenteric estrogen-dependent adipogenesis protein

    gene.name: MEDAG
  2. 5 Metabolomics

    Study Name: LIPID MAPS Lipidomics studies

    Grant ID: U01 DK097430-01

    Grant: NIGMS

    study.usesReagent.material.name: MeDAG(60:2)
  3. Chronic sublethal exposure to silver nanoparticles disrupts thyroid hormone signaling during Xenopus laevis metamorphosis BioProject

    ID: PRJNA242206

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: y-relevant nAg concentrations (LoAg, 0.018 µg/L; MedAg, 0.18 µg/L; HiAg, 1.8 µg/L) on naturally metamorphosing Xenopus laevis tadpoles in two 28-day chronic exposures beginning with pre- and prometamorphic stages, respectively. nAg was found to significantly bioaccumulate in tadpoles after 28 days. While nAg didn’t alter metamorphic timing, it increased hindlimb length during early premetamorphosis and in post-metamorphic juvenile tadpoles. Using MAGEX microarray and QPCR transcript analyses, 7 markers of nAg exposure were discovered and validated, 5 of which showed nAg-induced disruption of their TH-response. The increased mRNA abundance of two peroxidase genes suggests that nAg could generate reactive oxygen species (ROS) even at low, environmental concentrations. Furthermore, differential responsiveness to nAg was observed between developme...

Displaying 3 of 3 results for "MEDAG"