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Displaying 20 of 197 results for "MAP3K1"
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  1. Deciphering Gene Expression Program of MAP3K1 in Mouse Eyelid Morphogenesis ArrayExpress

    ID: E-GEOD-39240

    Description: mitogen-activated protein kinase kinase kinase 1 (MAP3K1) is essentially required for eyelid closure. We used microarray to characterize the central role that MAP3K1 plays in embryonic eyelid closure. We used Laser Capture Microdissection (LCM) to obtain highly enriched eyelid leading edge and inner eyelid cells from E15.5 wild type and MAP3K1-deficient fetuses and analyze genome-wide expr...

  2. Deciphering Gene Expression Program of MAP3K1 in Mouse Eyelid Morphogenesis BioProject

    ID: PRJNA170306

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Deciphering Gene Expression Program of MAP3K1 in Mouse Eyelid Morphogenesis OmicsDI

    ID: E-GEOD-39240

    Date Released: 09-26-2012

    Description: mitogen-activated protein kinase kinase kinase 1 (MAP3K1) is essentially required for eyelid closure. We used microarray to characterize the central role that MAP3K1 plays in embryonic eyelid closure. We used Laser Capture Microdissection (LCM) to obtain highly enriched eyelid leading edge and inner eyelid cells from E15.5 wild type and MAP3K1-deficient fetuses and analyze genome-wide expr...

  4. Transcription profiling of Th17 cells from mice expressing Mekk1 without catalytic domain (Map3k1∆KD) and control mice ArrayExpress

    ID: E-MTAB-4499

    Description: l mice will demonstrate whether Mekk1 (encoded by Map3k1) signaling activates Jnks to regulate cell cycle molecules and proliferative expansion. Comparative transcriptional profiling of Th17 molecular expression between experimental and control genotypes will reveal molecular targets that could play a role in the

  5. Transcription profiling by array of Map3k1 control and mutant mice to investigate iNKT gene expression ArrayExpress

    ID: E-MTAB-1561

    Description: Transcriptional profiling of iNKT gene expression in Map3k1 control and mutant mice

  6. ling by array of embryonic stem cells from mutant Map3k1 mice in comparison to control EL14 cells to investigate molecular mechanisms regulating MAPK signaling in embryonic stem cells... ArrayExpress

    ID: E-MTAB-1679

    Description: ne expression of embryonic stem cells from mutant Map3k1 mice in comparison to control EL14 cells. The differential expression of specific genes between the mutant and control groups generated from the microarray...

  7. Transcription profiling by array of Map3k1 control and mutant mice to investigate iNKT gene expression OmicsDI

    ID: E-MTAB-1561

    Date Released: 05-29-2015

    Description: Transcriptional profiling of iNKT gene expression in Map3k1 control and mutant mice

  8. Transcription profiling of Th17 cells from mice expressing Mekk1 without catalytic domain (Map3k1∆KD) and control mice OmicsDI

    ID: E-MTAB-4499

    Date Released: 08-31-2016

    Description: l mice will demonstrate whether Mekk1 (encoded by Map3k1) signaling activates Jnks to regulate cell cycle molecules and proliferative expansion. Comparative transcriptional profiling of Th17 molecular expression between experimental and control genotypes will reveal molecular targets that could play a role in the

  9. Homo sapiens : Estrogen Receptor Positive Breast Cancer Aromatase Inhibitor Response Study BioProject

    ID: PRJNA89531

    Access Type: download

    dataset.description: multiple markers of poor outcome and mutations in MAP3K1 associated with inferior clinical response. Mutations in MAP3K1 and MAP2K4 were mutually exclusive and positively associated with mutations in PIK3CA. The majority of tumors were multiclonal, as defined by distinct mutation clusters... (for more see dbGaP study page.)...
  10. Estrogen Receptor Positive Breast Cancer Aromatase Inhibitor Response Study BioProject

    ID: PRJNA157235

    Keywords: Phenotype or Genotype

    Access Type: download

    dataset.description: multiple markers of poor outcome and mutations in MAP3K1 associated with inferior clinical response. Mutations in MAP3K1 and MAP2K4 were mutually exclusive and positively associated with mutations in PIK3CA. The majority of tumors were multiclonal, as defined by distinct mutation clusters... (for more see dbGaP study page.)...
  11. ling by array of embryonic stem cells from mutant Map3k1 mice in comparison to control EL14 cells to investigate molecular mechanisms regulating MAPK signaling in embryonic stem cells... OmicsDI

    ID: E-MTAB-1679

    Date Released: 05-29-2015

    Description: ne expression of embryonic stem cells from mutant Map3k1 mice in comparison to control EL14 cells. The differential expression of specific genes between the mutant and control groups generated from the microarray...

  12. Transcription profiling of mouse activin treated MEKK1 wild type and KO keratinocytes ArrayExpress

    ID: E-MEXP-355

    Description: MEKK1 wildtype and knockout keratinocytes were compared both with and without activin (10 ng/ml) treatment for 12 hours, and control vs activin treate...

  13. M3K1_HUMAN UniProt:Swiss-Prot

    ID: Q13233

    Description: d-type and enhances binding of RHOA to the mutant MAP3K1 complex; dbSNP:rs387906788. In SRXY6; increases phosphorylation of the downstream targets MAPK14 and MAPK3/MAPK1 compared to wild-type and enhances binding of RHOA to the mutant MAP3K1 complex; dbSNP:rs387906788. In SRXY6. In SRXY6; dbSNP:rs143853590. In dbSNP:rs702689. In dbSNP:rs832582. (in Ref. 2; AAC97073) (in Ref. 2; AAC97073) (in Ref. 2; AAC97073) (in Ref. 2; AAC97073) (in Ref. 2; AAC97073) (in Ref. 2; AAC97073) (in Ref. 2; AAC97073) (in Ref. 2; AAC97073) (in Ref. 2; AAC97073) (in Ref. 2; AAC97073) (in Ref. 2; AAC97073)...

  14. Transcriptome of mkk1-mkk2 mutants ArrayExpress

    ID: E-GEOD-24516

    Description: au08-02_mkk1-mkk2 - mkk1-mkk2 - Functional redundancy of the two MAPKKs MKK1 and MKK2. - mkk1 and mkk2 k.o. plants were crossed. Seedlings homozygous ...

  15. Transcriptome of mkk1-mkk2 mutants BioProject

    ID: PRJNA132597

    Keywords: Transcriptome or Gene expression

    Access Type: download

  16. Homo sapiens : Genetic analysis of desmoplastic melanoma BioProject

    ID: PRJNA293389

    Access Type: download

    dataset.description: 3% of samples, affecting NF1, CBL, ERBB2, MAP2K1, MAP3K1, BRAF, EGFR, PTPN11, MET... (for more see dbGaP study page.)...
  17. Genetic analysis of desmoplastic melanoma BioProject

    ID: PRJNA293390

    Keywords: Phenotype or Genotype

    Access Type: download

    dataset.description: 3% of samples, affecting NF1, CBL, ERBB2, MAP2K1, MAP3K1, BRAF, EGFR, PTPN11, MET... (for more see dbGaP study page.)...
  18. Expression changes in mRNA expression associated with the effects of nutrition on apoptosis and spermatogenesis in the adult testis BioProject

    ID: PRJNA282344

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ong these gene modules, seven (CFLAR, PTPRC, F2R, MAP3K1, EPHA7, APP, BCAP31) were also differentially expressed between nutritional treatments, indicating their potential as markers of spermatogenesis or apoptosis. We conclude that under-nutrition causes changes in mRNAs and pre-mRNA alternative splicing that, at least partly, contribute to disrupted spermatogenesis and increased germ cell apoptosis. Overall design: Two groups of 8 male sheep were fed for a 10% increase or 10% decrease in body mass over 65 days, and the small RNA expression was profiled....
  19. The ureic-based herbicide linuron and the model anti-androgen flutamide regulate common gene networks in the fathead minnow (Pimephales promelas) ovar... ArrayExpress

    ID: E-GEOD-38287

    Description: on sub-networks (e.g. beta-3 adrenergic receptor, MAP3K1, interleukin, signlaing) in common with FLUT, and only 4 sub-networks with DHT. A reciprocal gene expression network was constructed using DHT and FLUT data, and the network revealed that steroid metabolism, translation, and DNA replication are potentially regulated through AR signaling. This study characterizes cell pathways associated with E2 production and identifies cell signaling cascades that may be disrupted by ureic-based herbicides in the ovary. 16 samples total; 4 control, 4 DHT, 4 Flutamide, 4 LIN...

  20. Estrogen Receptor Positive Breast Cancer: Aromatase Inhibitor Response Study OmicsDI

    ID: phs000472.v1.p1

    Date Released:

    Description: multiple markers of poor outcome and mutations in MAP3K1 associated with inferior clinical response. Mutations in MAP3K1 and MAP2K4 were mutually exclusive and positively associated with mutations in PIK3CA. The majority of tumors were multiclonal, as defined by distinct mutation clusters. A number of potential therapeutic targets were provided by both common and rare variants. Potential therapeutically relevant mutations of tryosine kinase included ERBB2, KIT, PDGFRA, DDR1, CSF1R, and MET.

    ...


Displaying 20 of 197 results for "MAP3K1"