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Displaying 20 of 70 results for "LTB"
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  1. Structure of heterotrimeric lymphotoxin LTa1b2 bound to lymphotoxin beta receptor LTbR and anti-LTa Fab PDB

    ID: PDB:4MXW

    Description: Tumor necrosis factor receptor superfamily member 3, anti-Lymphotoxin alpha antibody light chain, anti-

  2. Parvularcula sp. P33 : Parvularcula sp. P33 Genome Sequencing BioProject

    ID: PRJNA170400

    Keywords: Genome sequencing

    Access Type: download

  3. Clostridioides difficile P33 : Clostridioides difficile P33 Genome sequencing and assembly BioProject

    ID: PRJNA86005

    Keywords: Genome sequencing and assembly

    Access Type: download

  4. Transcription profiling of mouse aorta smooth muscle cells reveals they differentiate into lymphoid tissue organizers upon combined TNFR1/LTBR NF-kB s... ArrayExpress

    ID: E-GEOD-15062

    Description: Mouse aorta smooth muscle cells (SMCs) express TNF receptor superfamily member 1A (TNFR1) and lymphotoxin ß receptor (LT...

  5. Sporosarcina sp. P33 : Sporosarcina sp. P33 Genome sequencing and assembly BioProject

    ID: PRJNA316714

    Keywords: genome sequencing and assembly

    Access Type: download

  6. Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizers upon combined TNFR1/LTBR NF-kB signaling GEMMA

    ID: 2613

    Keywords: functional genomics

    Description: Mouse aorta smooth muscle cells (SMCs) express TNF receptor superfamily member 1A (TNFR1) and lymphotoxin ß receptor (LT...

  7. Blood Transcriptional Profiles of TB in South Africa ArrayExpress

    ID: E-GEOD-19442

    Description: um Tuberculosis on culture of sputum. Latent TB: LTB - All patients were screened at a tuberculosis clinic. All were positive by Interferon-Gamma Release assay(IGRA); specifically Quantiferon Gold In-Tube Assay (Cellestis, Australia). Latent patients had no clinical, or microbiological evidence of active infection and were asymptomatic. Experimental Variables: Patient group: Active PTB; Latent TB. There are no healthy controls in this dataset as it was being used for validation only. Controls: Latent TB individuals are used as a control for PTB in this dataset sin...

  8. Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizers upon combined TNFR1/LTBR NF-kB signaling BioProject

    ID: PRJNA114833

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Mouse aorta smooth muscle cells (SMCs) express TNF receptor superfamily member 1A (TNFR1) and lymphotoxin ß receptor (LT...
  9. Transcription profiling by array of human macrophages from tuberculosis patients stimulated with M. tuberculosis whole cell lysate ArrayExpress

    ID: E-GEOD-11199

    Description: o Mtb- stimulated macrophages in 12 subjects with 3 clinical phenotypes: latent, pulmonary and meningeal tuberculosis (n=4 per group). After identifying differentially expressed genes, we confirmed these results in 34 additional subjects by real-time PCR. We also used a case-control study design to examine whether polymorphisms in differentially regulated genes were associated with susceptibility to these different clinical forms of TB. We compared gene expression profiles in Mtb-stimulated and unstimulated macrophages and identified 1608 and 199 genes that were differentially expressed by >2 and >5-fold, respe...

  10. Implications of the miR-10 family in chemotherapy response of NPM1 mutated AML ArrayExpress

    ID: E-GEOD-55519

    Description: MD Anderson Cancer Center Leukemia Tissue Bank (LTB) using the Ohio State University (OSU) miRNA microarray (ver.3)....

  11. Transcription profiling of mouse MRP14(S100A9)-positive and -negative bone marrow granulocytes under different stimulations ArrayExpress

    ID: E-GEOD-3079

    Description: at time point 4h) and then stimulated for 4h with LTB-4 (1 repeat each), A23187 (a calcium ionophore, 4 repeats each), LPS (part of gram negative bacteria, 3 repeats each) and PMA (1 repeat each); MRP14(SA100A9)-positive and -negative mouse spleen tissue (1 repeat each) for comparison; another data set contains all experiments of this data set with Mu11KsubA instead of Mu11KsubB arrays...

  12. Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation ArrayExpress

    ID: E-GEOD-6952

    Description: To find developmental stage specific genes controled by EDA Keywords: development or differentiation design,genetic modification design Triplicated fo...

  13. Development of gene expression signatures for latent and clinical tuberculosis (TB) ArrayExpress

    ID: E-GEOD-27882

    Description: lls between healthy control, latent tuberculosis (LTB) and clinical tuberculosis (TB). Our experiment included 4 groups: healthy donor (HD), latent TB1 (LTB1) with low IFN-gamma release level, latent TB2 (LTB2) with high IFN-gamma release level, and tuberculosis (TB) with high IFN-gamma release level. Human peripheral blood mononuclear cells were collected, from which CD4+T cells were isolated. ...

  14. Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation BioProject

    ID: PRJNA99345

    Keywords: Transcriptome or Gene expression

    Access Type: download

  15. VP33_BPPRD UniProt:Swiss-Prot

    ID: Q3T4N8

    Description: Protein P33

  16. Blood Transcriptional Profiles in Active and Latent Tuberculosis UK (Training Set) ArrayExpress

    ID: E-GEOD-19439

    Description: tum or bronchoalvelolar lavage fluid. Latent TB: LTB - All patients were screened at a tuberculosis clinic, being either new entrants to the UK from endemic countries or being household contacts of infectious cases. All were positive by tuberculin skin test (>14mm if BCG vaccinated, >5mm if not vaccinated) and were also positive by Interferon-Gamma Release assay(IGRA); specifically Quantiferon Gold In-Tube Assay (Cellestis, Australia). Latent patients had no clinical, radiological or microbiological evidence of active infection and were asymptomatic. Healthy controls - these were volunteers without exposure to TB who were negative by both tuberculin skin test (<15mm if BCG vaccinated, <6mm if unvaccinated); who were also negative by IGRA (as described above). In this dataset: PTB n= 13; LTB n = 17; BCG+ n = 6, BCG-, n =6. Experimental variables : Patient group: Active PTB; Latent TB, Healthy controls (BCG vaccinated and unvaccinated). ethnicity - a wide range of ethnic groups is represented. However all controls in this dataset are broadly Caucasian/White. The active PTB group incorporates a range of smear positive and smear negative disease and a spectrum of disease extent/severity....

  17. Transcription profiling by array of human CD16+ and CD16- peripheral blood monocytes from healthy individuals ArrayExpress

    ID: E-GEOD-16836

    Description: raction (CXCL16, ICAM-2, LFA-1), cell activation (LTB, TNFRSF8, LST1, IFITM1-3, HMOX1, SOD-1, WARS, MGLL), and negative regulation of the cell cycle (CDKN1C, MTSS1), whereas CD16- Mo were distinguished by upregulation of myeloid (CD14, MNDA, TREM1, CD1d, C1qR/CD93) and granulocyte markers (FPR1, GCSFR/CD114, S100A8-9/12). Differential gene expression in CD16+ and CD16- Mo was confirmed by quantitative real time RT-PCR (i.e., CD16, C3AR1, C1QR1, ICAM-2, CSF1R, CSF3R, CDKN1C, TNFRSF1, and LTB) and flow cytometry (i.e., CSF1R, CSF3R, C1QR1, C3AR1, CD1d, CD43, CXCL16, and CX3CR1). Furthermore, increased expression of RARA and KLF2 transcripts in CD16+ Mo coincided with absence of cutaneous lymphocyte associated antigen (CLA) expression, indicating potential imprinting for non-skin homing. These results suggest that CD16+ and CD16- Mo originate from a common myeloid precursor, with CD16+ Mo having a more MF- and DC-like transcription program suggesting a more advanced stage of differentiation. Distinct transcriptional programs, together with their recruitment into tissues via different mechanisms, also sug...

  18. IRF4, a master transcription factor, regulates genes involved in BCR signaling, antigen processing and presentation, and GC development [expression ar... ArrayExpress

    ID: E-GEOD-64269

    Description: F4 possibly in some way involved to regulate LTA, LTB and CXCR5 those involved in immune system development, particularly light zone development related genes such as FDC clustering regulating and IL21R and IL10 who are involved in B cell development.. On the other hand, IRF4 suppressesd genes in the oxidative phosphorylation pathway. Our findings illuminate hitherto unexplored roles of IRF4 in GC B cell development. BL2 Burkitt's lymphoma-derived B cells were infected with lentivirus expressing shRNA for IRF4 or control, and total RNA was subjected to Illumina BeadsExpression Arrays analysis....

  19. Blood Transcriptional Profiles of Active and Latent TB (UK Test Set) BioProject

    ID: PRJNA123925

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: tum or bronchoalvelolar lavage fluid. Latent TB: LTB - All patients were screened at a tuberculosis clinic, being either new entrants to the UK from endemic countries or being household contacts of infectious cases. All were positive by tuberculin skin test (>14mm if BCG vaccinated, >5mm if not vaccinated) and were also positive by Interferon-Gamma Release assay(IGRA); specifically Quantiferon Gold In-Tube Assay (Cellestis, Australia). Latent patients had no clinical, radiological or microbiological evidence of active infection and were asymptomatic. Healthy controls - these were volunteers without exposure to TBwho were negative by both tuberculin skin test (<15mm if BCG vaccinated, <6mm if unvaccinated); who were also negative by IGRA (as described above). This dataset: PTB, n= 21. LTB, n = 21. BCG+, n = 12. Experimental variables : Patient group: Active PTB; Latent TB, Healthy controls (BCG vaccinated only). ethnicity - a wide range of ethnic groups is represented. The active PTB group incorporates a range of smear positive and smear negative disease and a spectrum of disease extent/severity....
  20. Blood Transcriptional Profiles of TB in South Africa BioProject

    ID: PRJNA123921

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: um Tuberculosis on culture of sputum. Latent TB: LTB - All patients were screened at a tuberculosis clinic. All were positive by Interferon-Gamma Release assay(IGRA); specifically Quantiferon Gold In-Tube Assay (Cellestis, Australia). Latent patients had no clinical, or microbiological evidence of active infection and were asymptomatic. Experimental Variables: Patient group: Active PTB; Latent TB. There are no healthy controls in this dataset as it was being used for validation only. Controls: Latent TB individuals are used as a control for PTB in this dataset since there are few...

Displaying 20 of 70 results for "LTB"