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Displaying 20 of 24 results for "LMO1"
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  1. SCL and LMO1 reprogram thymocytes into self-renewing cells. BioProject

    ID: PRJNA301090

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. SCL and LMO1 reprogram thymocytes into self-renewing cells ArrayExpress

    ID: E-GEOD-74659

    Description: The SCL and LMO1 oncogenic transcription factors reprogram thymocytes into self-renewing pre-leukemic stem cells (pre-LSCs). Here we report tha...

  3. Genetic predisposition to neuroblastoma mediated by a single nucleotide polymorphism within a LMO1 oncogene super-enhancer element BioProject

    ID: PRJNA274662

    Keywords: Epigenomics

    Access Type: download

  4. SCL and LMO1 reprogram thymocytes into self-renewing cells. OmicsDI

    ID: E-GEOD-74659

    Date Released: 12-01-2015

    Description: The SCL and LMO1 oncogenic transcription factors reprogram thymocytes into self-renewing pre-leukemic stem cells (pre-LSCs). Here we report tha...

  5. APOBEC Signature Mutation Forms an Oncogenic Enhancer Upstream of LMO1 in T-ALL BioProject

    ID: PRJNA369547

    Keywords: Epigenomics

    Access Type: download

  6. Transcription profiling of Medicago truncatula Mt TTG1 mutant seed ArrayExpress

    ID: E-MEXP-1757

    Description: Medicago truncatula Tnt-1 insertional mutant for MtTTG1 gene (NF977) versus the wild-type R108. The seed samples are harvested at 16 days after pollin...

  7. Gene expression signature of the T-ALL cell line LOUCY treated with 250nM (+)-JQ1 for 4h BioProject

    ID: PRJNA323419

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: utative oncogenes such as BAALC, WT1, MN1, MEF2C, LMO1 and LMO2. Genes associated with the 500 highest ranked enhancer regions in LOUCY, were significantly enriched in genes downregulated after JQ1 treatment. Overall design: LOUCY cells were treated with 250nM (+)-JQ1 or DMSO for 4h. Three biological replicates of this treatment were performed....
  8. ChIP-Seq of TAL1 and its regulatory partners in T-ALL cells ArrayExpress

    ID: E-GEOD-29180

    Description: led by TAL1 and its regulatory partners HEB, E2A, LMO1, LMO2, GATA3 and RUNX1 in T-ALL cells. We show that TAL1 forms an interconnected auto-regulatory loop with its partners, and that the TAL1 complex directly activates the MYB oncogene, forming a feed-forward positive regulatory loop that further promotes the TAL1-regulated oncogenic program. one of the cirtical downstream targets in this circuitry is the TRIB2 gene, which is oppositely regulated ...

  9. Transcription profiling of Medicago sativa MtTTG1 over-expression transgenic alfalfa gene ArrayExpress

    ID: E-MEXP-1759

    Description: Transcriptomics analysis of transgenic alfalfa (TTG1) versus gus control (GUS) in the cultivar R2336.

  10. Gene expression signature of the T-ALL cell line LOUCY treated with 1µM (+)-JQ1 for 48h BioProject

    ID: PRJNA323424

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: utative oncogenes such as BAALC, WT1, MN1, MEF2C, LMO1, LMO2, BCL2, IGFBP7, ZEB2, GFI1B, MYB and LYL1. Overall design: LOUCY cells were treated with 1µM (+)-JQ1 or DMSO for 48h. Three biological replicates of this treatment were performed....
  11. ChIP-Seq of TAL1 and its regulatory partners in T-ALL cells BioProject

    ID: PRJNA142977

    Keywords: Epigenomics

    Access Type: download

    dataset.description: led by TAL1 and its regulatory partners HEB, E2A, LMO1, LMO2, GATA3 and RUNX1 in T-ALL cells. We show that TAL1 forms an interconnected auto-regulatory loop with its partners, and that the TAL1 complex directly activates the MYB oncogene, forming a feed-forward positive regulatory loop that further promotes the TAL1-regulated oncogenic program. one of the cirtical downstream targets in this circuitry is the TRIB2 gene, which is oppositely regulated ...
  12. Core transcriptional regulatory circuit controlled by the tal1 complex in human t-cell acute lymphoblastic leukemia (Subseries) BioProject

    ID: PRJNA148179

    Keywords: Epigenomics

    Access Type: download

    dataset.description: Santa Cruz SC-357),TCF3/E2A (Santa Cruz SC-349X), LMO1 (Santa Cruz SC-10494), LMO2 (R&D Systems AF2726), GATA3 (Santa Cruz SC-22206) and RUNX1 (Santa Cruz SC-8563). This represents the ChIP-seq portion of this dataset. Human Jurkat cells were cross-linked with formaldehyde for 20 min. DNA was enriched by chromatin immunoprecipitation (ChIP) and analyzed by Solexa sequencing. A sample of whole cell extract (WCE) was sequenced and used as the background to determine enrichment. ChIP was performed using an antibody against total TAL1 (Santa Cruz SC-12984), TCF12/HEB (Santa Cruz SC-357),TCF3/E2A (Santa Cruz SC-349X), LMO1 (Santa Cruz SC-10494), GATA3 (Santa Cruz SC-22206) and RUNX1 (Santa Cruz SC-8563). This represents the ChIP-seq portion of this dataset....
  13. Core transcriptional regulatory circuit controlled by the tal1 complex in human t-cell acute lymphoblastic leukemia (Subseries) ArrayExpress

    ID: E-GEOD-33850

    Description: Santa Cruz SC-357),TCF3/E2A (Santa Cruz SC-349X), LMO1 (Santa Cruz SC-10494), LMO2 (R&D Systems AF2726), GATA3 (Santa Cruz SC-22206) and RUNX1 (Santa Cruz SC-8563). This represents the ChIP-seq portion of this dataset. Human Jurkat cells were cross-linked with formaldehyde for 20 min. DNA was enriched by chromatin immunoprecipitation (ChIP) and analyzed by Solexa sequencing. A sample of whole cell extract (WCE) was sequenced and used as the background to determine enrichment. ChIP was performed using an antibody against total TAL1 (Santa Cruz SC-12984), TCF12/HEB (Santa Cruz SC-357),TCF3/E2A (Santa Cruz SC-349X), LMO1 (Santa Cruz SC-10494), GATA3 (Santa Cruz SC-22206) and RUNX1 (Santa Cruz SC-8563). This represents the ChIP-seq portion of this dataset....

  14. ChIP-Seq of TAL1 and its regulatory partners in T-ALL cells OmicsDI

    ID: E-GEOD-29180

    Date Released: 03-21-2012

    Description: led by TAL1 and its regulatory partners HEB, E2A, LMO1, LMO2, GATA3 and RUNX1 in T-ALL cells. We show that TAL1 forms an interconnected auto-regulatory loop with its partners, and that the TAL1 complex directly activates the MYB oncogene, forming a feed-forward positive regulatory loop that further promotes the TAL1-regulated oncogenic program. one of the cirtical downstream targets in this circuitry is the TRIB2 gene, which is oppositely regulated ...

  15. RBTN1_XENLA UniProt:Swiss-Prot

    ID: Q3B8H4

    Description: Rhombotin-1 LIM zinc-binding 1 LIM zinc-binding 2

    gene.name: lmo1
  16. RBTN1_DANRE UniProt:Swiss-Prot

    ID: Q8JFQ2

    Description: Rhombotin-1 LIM zinc-binding 1 LIM zinc-binding 2

    gene.name: lmo1
  17. A compendium of hematopoietic regulators, chromatin modifiers and basal transcription factors occupy CBF-MYH11/RUNX1 target genes ArrayExpress

    ID: E-GEOD-46044

    Description: poietic stem cell (HSC) self-renewal such as ID1, LMO1 and JAG1, are actively transcribed and upon fusion protein knock down repressed. Together these results suggest an essential role for CBF-MYH11 in regulating expression of genes involved in maintaining a stem cell phenotype. 17 ChIP-seq samples using antibodies recognizing the indicated proteins and one RNA-seq file from ME-1 cells were analyzed. In addition 2 ChIP-seq profiles were generated using patient AML cells. A CBFβ-MYH11 inducible U937 system (U937CM) was used to examine binding patterns before (1 profile) and after (2 profiles) induction of CBFb-MYH11. In addition, expression was measured through RNA-seq analysis of the two states. The U937CM cells were maintained in the presence of tetracyclin (Tet, 1 uM) and grown in the absence of tetracycline for 3 days to induce expression of CBFβ-MYH11. Finally, a CBFb-MYH11 knock down system was developed in ME-1 cells. Two ME-1 cell lines were created, one with a stably integrated shRNA construct that targets CBFb-MYH11 (ME-1_knockdown) and one with a scrambled shRNA construct (ME-1_SCR). Expressio...

  18. Core transcriptional regulatory circuit controlled by the tal1 complex in human t-cell acute lymphoblastic leukemia (Subseries) OmicsDI

    ID: E-GEOD-33850

    Date Released: 03-11-2013

    Description: Santa Cruz SC-357),TCF3/E2A (Santa Cruz SC-349X), LMO1 (Santa Cruz SC-10494), LMO2 (R&D Systems AF2726), GATA3 (Santa Cruz SC-22206) and RUNX1 (Santa Cruz SC-8563). This represents the ChIP-seq portion of this dataset. Human Jurkat cells were cross-linked with formaldehyde for 20 min. DNA was enriched by chromatin immunoprecipitation (ChIP) and analyzed by Solexa sequencing. A sample of whole cell extract (WCE) was sequenced and used as the background to determine enrichment. ChIP was performed using an antibody against total TAL1 (Santa Cruz SC-12984), TCF12/HEB (Santa Cruz SC-357),TCF3/E2A (Santa Cruz SC-349X), LMO1 (Santa Cruz SC-10494), GATA3 (Santa Cruz SC-22206) and RUNX1 (Santa Cruz SC-8563). This represents the ChIP-seq portion of this dataset....

  19. A compendium of hematopoietic regulators, chromatin modifiers and basal transcription factors occupy CBF-MYH11/RUNX1 target genes BioProject

    ID: PRJNA197000

    Keywords: Other

    Access Type: download

    dataset.description: poietic stem cell (HSC) self-renewal such as ID1, LMO1 and JAG1, are actively transcribed and upon fusion protein knock down repressed. Together these results suggest an essential role for CBF-MYH11 in regulating expression of genes involved in maintaining a stem cell phenotype. Overall design: 17 ChIP-seq samples using antibodies recognizing the indicated proteins and one RNA-seq file from ME-1 cells were analyzed. In addition 2 ChIP-seq profiles were generated using patient AML cells. A CBFβ-MYH11 inducible U937 system (U937CM) was used to examine binding patterns before (1 profile) and after (2 profiles) induction of CBFb-MYH11. In addition, expression was measured through RNA-seq analysis of the two states. The U937CM cells were maintained in the presence of tetracyclin (Tet, 1 uM) and grown in the absence of tetracycline for 3 days to induce expression of CBFβ-MYH11. Finally, a CBFb-MYH11 knock down system was developed in ME-1 cells. Two ME-1 cell lines were created, one with a stably integrated shRNA construct that targets CBFb-MYH11 (ME-1_knockdown) and one with a scrambled shRNA construct (ME-1...
  20. Additional file 2: Table S1A. of Hairy Canola (Brasssica napus) re-visited: Down-regulating TTG1 in an AtGL3-enhanced hairy leaf background improves g... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3645929_D1

    Release Date: 12-16-2016

    Description: Primer sequences used in the construction and analysis of B. napus transgenic lines. Table S1B. Blast of batch leaf Q-PCR primers to the B. rapa, B. o...


Displaying 20 of 24 results for "LMO1"