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Displaying 20 of 21 results for "LGSN"
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  1. Lengsin is a survivor of an ancient family of class I glutamine synthetases in eukaryotes that has undergone evo... PDB

    ID: PDB:2J9I

    Description: GLUTAMATE-AMMONIA LIGASE DOMAIN-CONTAINING PROTEIN 1

  2. Genetic Analyses in Epileptic Encephalopathies BioProject

    ID: PRJNA219686

    Keywords: Phenotype or Genotype

    Access Type: download

    dataset.description: nfantile spasms (IS) and Lennox-Gastaut syndrome (LGS). The probands and parents studied were collected and phenotyped as part of the Epilepsy Phenome/Genome Project (EPGP). In this initial study, a total of 337 probands (IS, n=200, LGS, n=137) and their parents were exome sequenced and screened for de novo mutations....
  3. Genetic mapping with multiple levels of phenotypic information reveals new determinants of lymphocyte glucocorticoid sensitivity ArrayExpress

    ID: E-GEOD-48801

    Description: dely used as pharmaceuticals, varies extensively, with many patients (~30%) showing a weak response to treatment. Although little is known about the molecular basis of this variation, regulatory polymorphisms are likely to play a key role as GC...

  4. Genetic mapping with multiple levels of phenotypic information reveals new determinants of lymphocyte glucocorticoid sensitivity OmicsDI

    ID: E-GEOD-48801

    Date Released: 06-03-2014

    Description: dely used as pharmaceuticals, varies extensively, with many patients (~30%) showing a weak response to treatment. Although little is known about the molecular basis of this variation, regulatory polymorphisms are likely to play a key role as GC...

  5. Inter-ethnic differences in lymphocyte sensitivity to glucocorticoids reflect variation in transcriptional response ArrayExpress

    ID: E-GEOD-33649

    Description: we measured in vitro lymphocyte GC sensitivity (LGS) and transcriptome-wide response to GCs in peripheral blood mononuclear cells (PBMCs) from African-American and European-American healthy donors. We found that transcriptional response after 8hrs treatment was significantly correlated with variation in LGS within and between populations. We found that NFKB1, a gene previously found to predict LGS within populations, was more strongly downregulated in European-Americ...

  6. Genetic mapping with multiple levels of phenotypic information reveals new determinants of lymphocyte glucocorticoid sensitivity BioProject

    ID: PRJNA211814

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Inter-ethnic differences in lymphocyte sensitivity to glucocorticoids reflect variation in transcriptional response BioProject

    ID: PRJNA148657

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: we measured in vitro lymphocyte GC sensitivity (LGS) and transcriptome-wide response to GCs in peripheral blood mononuclear cells (PBMCs) from African-American and European-American healthy donors. We found that transcriptional response after 8hrs treatment was significantly correlated with variation in LGS within and between populations. We found that NFKB1, a gene previously found to predict LGS within populations, was more strongly downregulated in European-Americ...
  8. Inter-ethnic differences in lymphocyte sensitivity to glucocorticoids reflect variation in transcriptional response OmicsDI

    ID: E-GEOD-33649

    Date Released: 02-14-2012

    Description: we measured in vitro lymphocyte GC sensitivity (LGS) and transcriptome-wide response to GCs in peripheral blood mononuclear cells (PBMCs) from African-American and European-American healthy donors. We found that transcriptional response after 8hrs treatment was significantly correlated with variation in LGS within and between populations. We found that NFKB1, a gene previously found to predict LGS within populations, was more strongly downregulated in European-Americ...

  9. Cryptococcus neoformans var. neoformans : Genetic linkage map of serotype D (B-3501 x B-3502) BioProject

    ID: PRJNA15563

    Keywords: Map

    Access Type: download

    dataset.description: nd B-3502. They identified twenty linkage groups (LGs) based on segregation analysis of 301 polymorphic markers consisting of 228 restriction site polymorphisms, 63 microsatellites, two indels, and eight mating-type (MAT)-associated markers. Marra et al. assigned the LGs to specific chromosomes. All chromosomes except chromosome 10...
  10. Transcription profiling of rat lacrimal gland samples from normal, sham and operated animals OmicsDI

    ID: E-GEOD-844

    Date Released: 03-27-2012

    Description: anization of the LG. Long-Evans rats anesthetized with a mixture of ketamine/xylazine (80:10 mg/kg) underwent unilateral sectioning of the greater superficial petrosal nerve, the input to the pterygopalatine ganglion. After 7 days, tear secretion was measured, the animals were killed, and structural changes in the LG were examined by light microscopy. Total RNA from control and experimental LGs (n = 5) was used for DNA microarray analysis employing the U34A GeneChip. Cont...

  11. Control LG vs Px LG BioProject

    ID: PRJNA87853

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ralateral controls. Paired contralateral control LGs represent LG from the same animal, one side was operated and the other side unoperated. Keywords: repeat sample...
  12. Transcription profiling of rat lacrimal gland samples from normal, sham and operated animals ArrayExpress

    ID: E-GEOD-844

    Description: anization of the LG. Long-Evans rats anesthetized with a mixture of ketamine/xylazine (80:10 mg/kg) underwent unilateral sectioning of the greater superficial petrosal nerve, the input to the pterygopalatine ganglion. After 7 days, tear secretion was measured, the animals were killed, and structural changes in the LG were examined by light microscopy. Total RNA from control and experimental LGs (n = 5) was used for DNA microarray analysis employing the U34A GeneChip. Cont...

  13. Data from: Linkage map of the peppered moth, Biston betularia (Lepidoptera, Geometridae): a model of industrial melanism Dryad

    DateIssued: 02-19-2013

    Description: (AFLPs) and genes, consists of 31 linkage groups (LGs; consistent with the karyotype). Comparison with the evolutionarily distant Bombyx mori suggests that the gene content of chromosomes is highly conserved. Gene order is conserved on the autosomes, but noticeably less so on the Z chromosome, as confirmed by physical mapping using bacterial artificial chromosome fluorescence in situ hybridization (BAC-FISH). Synteny mapping identified three pairs of B. betularia LGs

  14. Data from: Deciphering the genomic architecture of the stickleback brain with a novel multi-locus gene-mapping approach Dryad

    DateIssued: 04-07-2017

    Description: ciphering the genetic architecture of such traits with traditional quantitative trait locus (QTL) mapping methods is challenging. Here, we investigated the genetic architecture of brain size (and the size of five different brain parts) in nine-spined sticklebacks (Pungitius pungitius) with the aid of n...

  15. Data from: A linkage disequilibrium perspective on the genetic mosaic of speciation in two hybridizing Mediterranean white oaks Dryad

    DateIssued: 04-16-2015

    Description: rs evenly distributed over the 12 linkage groups (LGs) of the oak linkage map to confirm the species genetic identity of the sampled genotypes, and searched for differentiation outliers. Then, we genotyped 29 additional markers from the chromosome bins containing the outliers and repeated the multilocus scans. We found one or two additional outliers within four saturated bins, thus confirming that outliers are organized into clusters. Linkage disequilibrium (LD) was extensive; even for loosely linked and for independent markers. Consequently, score tests for association between two-marker haplotypes and the ‘species trait’ showed a broad genomic divergence, although substantial va...

  16. Crystal Structure Analysis of the PHD domain of the Transcription Coactivator Pygophus PDB

    ID: PDB:2DX8

    Description: Pygopus homolog 1

  17. Structural analysis of PHD domain of Pygopus complexed with trimethylated histone H3 peptide PDB

    ID: PDB:2YYR

    Description: Pygopus homolog 1, H3K4Me3 peptide

  18. Additional file 8: Table S6. of Variations on a theme: Genomics of sex determination in the cichlid fish Astatotilapia burtoni Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3597857_D4

    Release Date: 12-14-2016

    Description: Gene expression details of genes with strongest male and female bias on LGs 5 and 14 as well as gene candidates on LG5. (XLSX 30 kb)...

  19. Brapa_BLUPs_for_qtlcart Dryad

    DateIssued: 12-23-2015

    Description: LOD= 4.1). We used R/QTL to order markers within LGs, passing the resulting best-supported positions of markers to a ripple function to explore alternative arrangements in a 5-marker sliding window. The resulting linkage map of ten chromosomes has an average distance of 0.79 cM between adjacent markers....

  20. Additional file 3: of Construction of a high-density genetic map using specific length amplified fragment markers and identification of a quantitative... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3597500_D5

    Release Date: 12-14-2016

    Description: SLAF markers on the 16 linkage groups (LGs). The SLAF markers and their locations in each LG on the maps. (XLS 404 kb)


Displaying 20 of 21 results for "LGSN"