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Displaying 2 of 2 results for "KLHL6"
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  1. RNA-seq of breast in 3-week and 6-week age native Pekin and Cherry Valley Pekin ducks BioProject

    ID: PRJNA358835

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Expression of cytokine-sensitive genes in islets from diabetes-prone mice BioProject

    ID: PRJNA265865

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: AIRg with SNPs in ARAP3 (5q31.3), F13A1 (6p25.3), KLHL6 (3q27.1), NID1 (1q42.3), PAMR1 (11p13), RIPK2 (8q21.3), and STEAP4 (7q21.12). These data support the mouse islet microarray data in detection of seven novel genes with potential importance to islet dysfunction in T2D. To further assess each gene, murine islets were exposed for 48-hrs to the following stressors representing models of beta-cell failure: 20nM rotenone (oxidative stress), 100nM thapsigargin (ER stress), 10pg/ml IL-1B + 20pg/ml IL-6 (cytokines/low-grade inflammation), 28mM glucose (hyperglycemia), or 50uM palmitate + 100uM oleate + 50uM linoleate (lipotoxicity). RT-PCR revealed that F13a1 was downregulated 3.3-fold by cytokines (P<0.05) and 2.6-fold by rotenone (P<0.05), Klhl6 was upre...

Displaying 2 of 2 results for "KLHL6"