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Displaying 14 of 14 results for "KIR2DL4"
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  1. Crystal structure of Killer cell immunoglobulin-like receptor 2DL4 PDB

    ID: PDB:3WYR

    Description: Killer cell immunoglobulin-like receptor 2DL4

    gene.name: KIR2DL4, CD158D, KIR103AS
  2. Epigenetic regulation of the transcriptional program in memory and terminally differentiated CD8+ T cells [HCAFIS_12_Gene_Expression] BioProject

    ID: PRJNA325147

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: LYN) and a large array of NK receptors (KIR2DL3, KIR2DL4, KIR2DL1, KIR3DL1, KIR2DS5, etc.). In addition, we identified up to 161 genes that encode transcriptional regulators, some of unknown function in CD8+ T cells, that were differentially expressed in the course of differentiation. Overall, these results provide new insights into the regulatory networks involved in memory CD8+ T cell maintenance and T cell terminal differentiation. Overall design: Genome-wide changes in gene Expression in naive CD8+ T cells control and after LEF1 knockdown were generated by Human HT12 v4 BeadChips (Illumina Inc.)....
  3. DNA Methylation Changes and Childhood Asthma in the Inner City [methylation] ArrayExpress

    ID: E-GEOD-40576

    Description: specific genes relevant to natural killer cells (KIR2DL4, KIR2DL3, KIR3DL1, and KLRD1) and T cells lymphocytes (TIGIT). 14 differentially methylated regions (DMRs) were associated with the serum IgE concentration of IgE, including RUNX3. These results were internally and externally validated with a global methylation assessment using a different methodology in our inner-city cohort and an independent European cohort (GABRIELA). Hypo- and hypermethylated genes tended to be associated with increased and decreased gene expression, respectively (P<0.6x10-11 for asthma and ; P<0.01 for IgE). To further explore the relationship between methylation and gene expression, we created a matrix of genomic changes in methylation versus transcriptional changes (methyl eQTL) for asthma, and identified cis- and trans-regulated genes whose expression was related to asthma asthma-associated methylation marks. peripheral blood mononuclear cells (PBMCs) from 97 atopic asthmatic and 97 nonatopic nonasthmatic children...

  4. DNA Methylation Changes and Childhood Asthma in the Inner City [gene expression] ArrayExpress

    ID: E-GEOD-40732

    Description: specific genes relevant to natural killer cells (KIR2DL4, KIR2DL3, KIR3DL1, and KLRD1) and T cells lymphocytes (TIGIT). 14 differentially methylated regions (DMRs) were associated with the serum IgE concentration of IgE, including RUNX3. These results were internally and externally validated with a global methylation assessment using a different methodology in our inner-city cohort and an independent European cohort (GABRIELA). Hypo- and hypermethylated genes tended to be associated with increased and decreased gene expression, respectively (P<0.6x10-11 for asthma and ; P<0.01 for IgE). To further explore the relationship between methylation and gene expression, we created a matrix of genomic changes in methylation versus transcriptional changes (methyl eQTL) for asthma, and identified cis- and trans-regulated genes whose expression was related to asthma asthma-associated methylation marks. peripheral blood mononuclear cells (PBMCs) from 97 atopic asthmatic and 97 nonatopic nonasthmatic children...

  5. Epigenetic regulation of the transcriptional program in memory and terminally differentiated CD8+ T cells [HCAFIS_07_Gene_Expression] BioProject

    ID: PRJNA325148

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: LYN) and a large array of NK receptors (KIR2DL3, KIR2DL4, KIR2DL1, KIR3DL1, KIR2DS5, etc.). In addition, we identified up to 161 genes that encode transcriptional regulators, some of unknown function in CD8+ T cells, that were differentially expressed in the course of differentiation. Overall, these results provide new insights into the regulatory networks involved in memory CD8+ T cell maintenance and T cell terminal differentiation. Overall design: Genome-wide changes in gene expression in human CD8+ T cell subsets isolated from peripheral blood were generated by Human HT12 v4 BeadChips (Illumina Inc.)...
  6. Epigenetic regulation of the transcriptional program in memory and terminally differentiated CD8+ T cells [HCAFIS_03_ChIPseq] BioProject

    ID: PRJNA325150

    Keywords: Epigenomics

    Access Type: download

    dataset.description: LYN) and a large array of NK receptors (KIR2DL3, KIR2DL4, KIR2DL1, KIR3DL1, KIR2DS5, etc.). In addition, we identified up to 161 genes that encode transcriptional regulators, some of unknown function in CD8+ T cells, that were differentially expressed in the course of differentiation. Overall, these results provide new insights into the regulatory networks involved in memory CD8+ T cell maintenance and T cell terminal differentiation. Overall design: Genome-wide changes in H3K9Ac and H3k9me3 in human CD8+ T cell subsets isolated from peripheral blood...
  7. Epigenetic regulation of the transcriptional program in memory and terminally differentiated CD8+ T cells [HCAFIS_05_Methylation] BioProject

    ID: PRJNA325149

    Keywords: Epigenomics

    Access Type: download

    dataset.description: LYN) and a large array of NK receptors (KIR2DL3, KIR2DL4, KIR2DL1, KIR3DL1, KIR2DS5, etc.). In addition, we identified up to 161 genes that encode transcriptional regulators, some of unknown function in CD8+ T cells, that were differentially expressed in the course of differentiation. Overall, these results provide new insights into the regulatory networks involved in memory CD8+ T cell maintenance and T cell terminal differentiation. Overall design: Genome-wide changes in DNA methylation in human CD8+ T cell subsets isolated from peripheral blood were generated by HumanMethylation450 (HM450) BeadChips (Illumina Inc.)...
  8. DNA Methylation Changes and Childhood Asthma in the Inner City [gene expression] BioProject

    ID: PRJNA174785

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: specific genes relevant to natural killer cells (KIR2DL4, KIR2DL3, KIR3DL1, and KLRD1) and T cells lymphocytes (TIGIT). 14 differentially methylated regions (DMRs) were associated with the serum IgE concentration of IgE, including RUNX3. These results were internally and externally validated with a global methylation assessment using a different methodology in our inner-city cohort and an independent European cohort (GABRIELA). Hypo- and hypermethylated genes tended to be associated with increased and decreased gene expression, respectively (P<0.6x10-11 for asthma and ; P<0.01 for IgE). To further explore the relationship between methylation and gene expression, we created a matrix of genomic changes in methylation versus transcriptional changes (methyl eQTL) for asthma, and identified cis- and trans-regulated genes whose expression was related to asthma asthma-associated methylation marks. Overall design: peripheral blood mononuclear cells (PBMCs) from 97 atopic asthmatic and 97 nonatopic nonasthmatic children...
  9. DNA Methylation Changes and Childhood Asthma in the Inner City [methylation] BioProject

    ID: PRJNA174784

    Keywords: Epigenomics

    Access Type: download

    dataset.description: specific genes relevant to natural killer cells (KIR2DL4, KIR2DL3, KIR3DL1, and KLRD1) and T cells lymphocytes (TIGIT). 14 differentially methylated regions (DMRs) were associated with the serum IgE concentration of IgE, including RUNX3. These results were internally and externally validated with a global methylation assessment using a different methodology in our inner-city cohort and an independent European cohort (GABRIELA). Hypo- and hypermethylated genes tended to be associated with increased and decreased gene expression, respectively (P<0.6x10-11 for asthma and ; P<0.01 for IgE). To further explore the relationship between methylation and gene expression, we created a matrix of genomic changes in methylation versus transcriptional changes (methyl eQTL) for asthma, and identified cis- and trans-regulated genes whose expression was related to asthma asthma-associated methylation marks. Overall design: peripheral blood mononuclear cells (PBMCs) from 97 atopic asthmatic and 97 nonatopic nonasthmatic children...
  10. DNA Methylation Changes and Childhood Asthma in the Inner City [gene expression] OmicsDI

    ID: E-GEOD-40732

    Date Released: 02-07-2015

    Description: specific genes relevant to natural killer cells (KIR2DL4, KIR2DL3, KIR3DL1, and KLRD1) and T cells lymphocytes (TIGIT). 14 differentially methylated regions (DMRs) were associated with the serum IgE concentration of IgE, including RUNX3. These results were internally and externally validated with a global methylation assessment using a different methodology in our inner-city cohort and an independent European cohort (GABRIELA). Hypo- and hypermethylated genes tended to be associated with increased and decreased gene expression, respectively (P<0.6x10-11 for asthma and ; P<0.01 for IgE). To further explore the relationship between methylation and gene expression, we created a matrix of genomic changes in methylation versus transcriptional changes (methyl eQTL) for asthma, and identified cis- and trans-regulated genes whose expression was related to asthma asthma-associated methylation marks. peripheral blood mononuclear cells (PBMCs) from 97 atopic asthmatic and 97 nonatopic nonasthmatic children...

  11. DNA Methylation Changes and Childhood Asthma in the Inner City [methylation] OmicsDI

    ID: E-GEOD-40576

    Date Released: 02-07-2015

    Description: specific genes relevant to natural killer cells (KIR2DL4, KIR2DL3, KIR3DL1, and KLRD1) and T cells lymphocytes (TIGIT). 14 differentially methylated regions (DMRs) were associated with the serum IgE concentration of IgE, including RUNX3. These results were internally and externally validated with a global methylation assessment using a different methodology in our inner-city cohort and an independent European cohort (GABRIELA). Hypo- and hypermethylated genes tended to be associated with increased and decreased gene expression, respectively (P<0.6x10-11 for asthma and ; P<0.01 for IgE). To further explore the relationship between methylation and gene expression, we created a matrix of genomic changes in methylation versus transcriptional changes (methyl eQTL) for asthma, and identified cis- and trans-regulated genes whose expression was related to asthma asthma-associated methylation marks. peripheral blood mononuclear cells (PBMCs) from 97 atopic asthmatic and 97 nonatopic nonasthmatic children...

  12. Cellular senescence reprograms human NK cells to promote vascular remodeling ArrayExpress

    ID: E-GEOD-35330

    Description: Natural killer (NK) cells are lymphocytes that participate in immune responses through their cytotoxic activity and secretion of cytokines and chemoki...

  13. Cellular senescence reprograms human NK cells to promote vascular remodeling BioProject

    ID: PRJNA152641

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. Determinants of human NK cell diversity by mass cytometry ImmPort

    ID: SDY232

    Description: Natural Killer (NK) cells play critical roles in immune defense and reproduction, yet remain the most poorly understood lymphocyte population. Because...

    molecularEntity.name: KIR2DL4-173Yb

Displaying 14 of 14 results for "KIR2DL4"