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Displaying 20 of 23 results for "KCNMA1"
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  1. Study of Differential Gene Expression in Metastatic Breast Tumors BioProject

    ID: PRJNA117767

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: though ubiquitously present in most human organs, calcium-activated potassium (BK) channel is significantly upregulated in breast cancer cells. In this study we investigated the role of KCNMA1 gene, which encodes α subunit of KCa channels (BK channels) in breast cancer metastasis and invasion. Methods: We per...
  2. Structure of the Intracellular Gating Ring from the Human High-conductance Ca2+ gated K+ Channel (BK Channel) PDB

    ID: PDB:3NAF

    Description: Calcium-activated potassium channel subunit

  3. Open Structure of the BK channel Gating Ring PDB

    ID: PDB:3U6N

    Description: High-Conductance Ca2+-Activated K+ Channel protein

  4. Borrelia parkeri SLO : Borrelia parkeri SLO Genome sequencing BioProject

    ID: PRJNA195597

    Keywords: Genome sequencing

    Access Type: download

  5. Regulation of global gene expression in human Loa loa infection is a function of chronicity BioProject

    ID: PRJNA145209

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Regulation of global gene expression in human Loa loa infection is a function of chronicity ArrayExpress

    ID: E-GEOD-31894

    Description: Differential gene expression to parasite and nonparasite antigen was seen in infected patients with lifelong exposure to the human filarial parasite L...

    datasetDistributions.accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-31894/E-GEOD-31894.raw.1.zip
  7. PRJEB1521 BioProject

    Keywords: Other

    Access Type: download

  8. KCMB2_HUMAN UniProt:Swiss-Prot

    ID: Q9Y691

    Description: Calcium-activated potassium channel subunit beta-2 Cyto...

  9. Cell Image Library Dataset CIL:12650 CIL

    ID: 12650

    Description: Spiroplasmas are bacteria in the Class Mollicutes that are frequently associated with insects and/or plants. This electron micrograph shows a negative...

    Data Types: image

  10. Gene-level expression data in melanocytes and in melanoma cell lines WM1552C and A375 over-expressing miR211 ArrayExpress

    ID: E-GEOD-15281

    Description: miR-211. Four such target genes (TCF12, RAB22A, KCNMA1 and SLC37A3) were confirmed by a target cleavage assay. Stable over-expression of miR-211 in two melanoma cell lines caused significant growth inhibition and reduced invasiveness. The differential expression of miR-211 in a variety of melanoma cell lines and clinical samples, consistent inverse correlation between miR-211 and its target mRNA levels, and growth retardation and reduced invasiveness of melanoma cell lines by miR-211 are all consistent with the idea that the depletion of miR-211 is a key step in melanoma development and/or progression The 15 Samples in this submission represent gene-level expression profiling of isolated total RNA from WM1552C, WM1552+miRNA211, A375, A375+miRNA211 and melanocytes hybridized to Affymetrix exon ararys....

  11. Gene expression profiles in group G streptococci during infection ArrayExpress

    ID: E-GEOD-43222

    Description: Streptococcus dysgalactiae subsp. equeisimilis (SDSE) has Lancefield group G or C antigens. Recent epidemiological studies reveal that invasive SDSE i...

    datasetDistributions.accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-43222/E-GEOD-43222.raw.1.zip
  12. A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice [expression profiling] BioProject

    ID: PRJNA354601

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: n of the methionine adenosyltransferase Mat2a and BK channel subunit Kcnmb2, which was associated with changes in Kcnmb2 promoter methylation in MD F1 mice. These phenomena did not extend into the F2 offspring generation. Together, our data indicate that paternal dietary factors influence cognitive and neural functions in the offspring generation. Overall design: 6 pools of 4 mouse hippocampal cDNA each from F1 and from F2...
  13. Rattus norvegicus breed:Sprague–Dawley : Rattus norvegicus breed:Sprague–Dawley Epigenomics BioProject

    ID: PRJNA310210

    Keywords: epigenomics

    Access Type: download

    dataset.description: d regions (DHMRs) in genes encoding voltage (Kv1. 1, Kv1. 2, Kvb1, and Kv2. 2)- and calcium (KCNMA1, KCNN1 and KCNN2)-gated potassium channels observed in the NAc of non-addicted rats were accompanied by increased mRNA levels of these potassium channels when compared to mRNA expression in METH-addicted rats. These observations indicate that changes in DHMRs and increased expression of specific potassium channels in the NAc may promote abstinence from drug taking behaviors. Thus, activation of specific subclasses of voltage- and/or calcium-gated potassium channels may provide an important approach to the beneficial treatment for METH addiction....
  14. Gene-level expression data in melanocytes and in melanoma cell lines WM1552C and A375 over-expressing miR211 BioProject

    ID: PRJNA116507

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: miR-211. Four such target genes (TCF12, RAB22A, KCNMA1 and SLC37A3) were confirmed by a target cleavage assay. Stable over-expression of miR-211 in two melanoma cell lines caused significant growth inhibition and reduced invasiveness. The differential expression of miR-211 in a variety of melanoma cell lines and clinical samples, consistent inverse correlation between miR-211 and its target mRNA levels, and growth retardation and reduced invasiveness of melanoma cell lines by miR-211 are all consistent with the idea that the depletion of miR-211 is a key step in melanoma development and/or progression Overall design: The 15 Samples in this submission represent gene-level expression profiling of isolated total RNA from WM1552C, WM1552+miRNA211, A375, A375+miRNA211 and melanocytes hybridized to Affymetrix exon ararys....
  15. Effects of MaxiK silencing in corporal smooth muscle cells ArrayExpress

    ID: E-GEOD-19672

    Description: The MaxiK potassium channel is a key modulator of smooth muscle tone. Due to its calcium and voltage se...

  16. Crystal Structure of the Human BK Gating Apparatus PDB

    ID: PDB:3MT5

    Description: Crystal Structure of the Human BK Gating Apparatus

  17. Hastings Reserve Annual Report Dryad

    DateIssued: 04-26-2011

    Description: Name: Dr. Walter Koenig Institution: UC Berkeley-MVZ HNHR Topic: Behavioral Ecology, Acorn Woodpeckers Funding Source: NSF Name: ...

  18. Streptococcus pyogenes strain:MTB314 : Streptococcus pyogenes MTB314 genome sequencing BioProject

    ID: PRJDB1668

    Keywords: Genome sequencing

    Access Type: download

    dataset.description: into MTB313. Then, MTB313 and MAT100 showed the large quantities of cell-associated HA in the cell pellets and the small quantities of SpeB associated with low activities in the culture supernatants. In contrast, MTB314 and MAT101 showed the opposite results. Meanwhile, the SLO production was much the same among these four strains in the culture supernatants. Finally, when the mortality rates by two weeks of these four strains were examined in a CD46-expressing transgenic mouse model of subcutaneous infection into both hind footpads, the higher mortalities were observed in the MTB313- or MAT100-infected mice than in the MTB314- or MAT101-infected mice. These results clearly indicate that the point mutation in the rocA gene of S. pyogenes led to the high-pathogenicity phenotype associated with the suppression of covR expression, which occurred within the patient....
  19. A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice [MeDIP_chip] BioProject

    ID: PRJNA354934

    Keywords: Epigenomics

    Access Type: download

    dataset.description: n of the methionine adenosyltransferase Mat2a and BK channel subunit Kcnmb2, which was associated with changes in Kcnmb2 promoter methylation in MD F1 mice. These phenomena did not extend into the F2 offspring generation. Together, our data indicate that paternal dietary factors influence cognitive and neural functions in the offspring generation. Overall design: Adult male mice were given either a normal laboratory control diet or a methyl-donor supplement diet containing added folic acid, L-methionine, choline, zinc, betaine and vitamine B12 for 6 weeks prior to mating. Their sperm DNA methylation, as well as their offspring (and grand-offspring) hippocampal methylation was evaluated using MeDIP-chip...
  20. Effects of MaxiK silencing in corporal smooth muscle cells BioProject

    ID: PRJNA122495

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: The MaxiK potassium channel is a key modulator of smooth muscle tone. Due to its calcium and voltage se...

Displaying 20 of 23 results for "KCNMA1"