JADE2 | bioCADDIE Data Discovery Index
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Displaying 7 of 7 results for "JADE2"
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  1. JADE1_DANRE UniProt:Swiss-Prot

    ID: Q803A0

    Description: Protein Jade-1 PHD-type 1 C2HC pre-PHD-type PHD-type 2

  2. JADE3_DANRE UniProt:Swiss-Prot

    ID: Q7ZVP1

    Description: Protein Jade-3 PHD-type 1 C2HC pre-PHD-type PHD-type 2

  3. JADE1_XENLA UniProt:Swiss-Prot

    ID: Q6GQJ2

    Description: Protein Jade-1 PHD-type 1 C2HC pre-PHD-type PHD-type 2 Poly-Ser...

  4. JADE3_XENTR UniProt:Swiss-Prot

    ID: Q0P4S5

    Description: Protein Jade-3 PHD-type 1 C2HC pre-PHD-type PHD-type 2

  5. JADE1_BOVIN UniProt:Swiss-Prot

    ID: Q5E9T7

    Description: Protein Jade-1 PHD-type 1 C2HC pre-PHD-type PHD-type 2 Phosphos...

  6. Dose-Responsive Gene Expression in Suberoylanilide Hydroxamic Acid (SAHA) Treated Resting CD4+ T Cells BioProject

    ID: PRJNA278662

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: e manner (FDR p-value < 0.05 and fold change ≥ |2|). Several of these genes (CTNNAL1, DPEP2, H1F0, IRGM, PHF15, and SELL) are potential in vivo biomarkers of SAHA activity. SAHA dose-responsive gene categories included transcription factors, HIV restriction factors, histone methyltransferases, and host proteins that interact with HIV proteins or the HIV LTR. Pathway analysis suggested net downregulation of T cell activation with increasing SAHA dose. Histone acetylation was not correlated with host expression, but plausible alternative mechanisms for SAHA-modulated expression were identified. Conclusions: Numerous host genes in CD4+ T cells are modulated by SAHA in a dose-responsive manner, including genes that may negatively influence HIV activation from latency. Our study suggests that SAHA influences gene expression through a confluence of several mechanisms, including histone acetylation, histone methylation, and altered expression and activity of transcription factors. Overall design: Primary CD4+ T cells were isolated from human peripheral blood drawn from 6 healthy HIV-seronegative donors. For each donor sample, CD4+ T cells were counted and aliquoted into 6-well plates; 5 million cells per well at a concentration of 2.5 million cells per mL of media (RPMI 1640 with 5% human serum AB). Wells containing CD4+ T cells we...
  7. Additional file 2: of Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3611990_D1

    Release Date: 12-14-2016

    Description: Supplemental datasheets. Datasheet S1: Summary of the annotation of the human and felid degradomes. Datasheet S2: List of orphan genes with expression...


Displaying 7 of 7 results for "JADE2"