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Displaying 20 of 20 results for "ITGB6"
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  1. Molecular mechanisms of cigarette smoke-induced lung emphysema ArrayExpress

    ID: E-MTAB-2756

    Description: ine expression, and reduced protein expression of ITGB6 and CFTR. We also corroborated, by using targeted proteomic approaches, several predictions such as reduced expression of ITGB6 and increased expression of BRCA1, C/EBPs, PU.1, TNF-a, IL-1b or CSF2. We believe this study will provide more insights into better understanding of CS-induced molecular processes underlying emphysema development in mice that may eventually be relevant in humans....

  2. Molecular mechanisms of cigarette smoke-induced lung emphysema OmicsDI

    ID: E-MTAB-2756

    Date Released: 07-16-2014

    Description: ine expression, and reduced protein expression of ITGB6 and CFTR. We also corroborated, by using targeted proteomic approaches, several predictions such as reduced expression of ITGB6 and increased expression of BRCA1, C/EBPs, PU.1, TNF-a, IL-1b or CSF2. We believe this study will provide more insights into better understanding of CS-induced molecular processes underlying emphysema development in mice that may eventually be relevant in humans....

  3. HAX1_BOVIN UniProt:Swiss-Prot

    ID: Q2KIE2

    Description: P2A2 binding Involved in PLN binding Required for ITGB6 binding Asp/Glu-rich (highly acidic) Cleavage; by caspase-3 N-acetylserine Phosphoserine...

  4. ITB6_PIG UniProt:Swiss-Prot

    ID: Q1RPR6

    Description: Integrin beta-6 Extracellular Helical Cytoplasmic VWFA I II III IV Cysteine-rich tandem repeats Interaction with HAX1 N-linked (GlcNAc...) N-linked (G...

    gene.name: ITGB6
  5. ITB6_CAVPO UniProt:Swiss-Prot

    ID: P18563

    Description: Integrin beta-6 Extracellular Helical VWFA I II III IV Cysteine-rich tandem repeats N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-l...

    gene.name: ITGB6
  6. ITB6_RAT UniProt:Swiss-Prot

    ID: Q6AYF4

    Description: Integrin beta-6 Extracellular Helical Cytoplasmic VWFA I II III IV Cysteine-rich tandem repeats Interaction with HAX1 N-linked (GlcNAc...) N-linked (G...

    gene.name: Itgb6
  7. ITB6_SHEEP UniProt:Swiss-Prot

    ID: Q863C4

    Description: Integrin beta-6 Extracellular Helical Cytoplasmic VWFA I II III IV Cysteine-rich tandem repeat Interaction with HAX1 N-linked (GlcNAc...) N-linked (Gl...

    gene.name: ITGB6
  8. Localised reconstruction of alpha v beta 6 bound to Foot and Mouth Disease Virus O PanAsia - Pose A prime PDB

    ID: PDB:5NER

    Description: Foot and mouth disease virus VP1, O PanAsia VP2, O PanAsia VP3, O PanAsia VP4, Integrin alpha-V, Integrin beta-6

    gene.name: ITGB6
  9. Crystal structure of integrin alpha V beta 6 head PDB

    ID: PDB:5FFG

    Description: Integrin alpha-V, Integrin beta-6

    gene.name: ITGB6
  10. Integrin alpha V beta 6 in complex with pro-TGF-beta PDB

    ID: PDB:5FFO

    Description: Integrin alpha-V, Integrin beta-6, Transforming growth factor beta-1

    gene.name: ITGB6
  11. Localised Reconstruction of Integrin alpha v beta 6 bound to Foot and Mouth Disease Virus O1 Manisa - Pose B PDB

    ID: PDB:5NEU

    Description: O1 Manisa VP1, O1 Manisa VP2, Capsid protein, O1 Manisa VP4, Integrin alpha-V, Integrin beta-6

    gene.name: ITGB6
  12. Localised Reconstruction of Integrin alpha v beta 6 bound to Foot and Mouth Disease Virus O1 Manisa - Pose A PDB

    ID: PDB:5NET

    Description: O1 Manisa VP1, O1 Manisa VP2, O1 Manisa VP3, O1 Manisa VP4, Integrin alpha-V, Integrin beta-6

    gene.name: ITGB6
  13. Localised reconstruction of alpha v beta 6 bound to Foot and Mouth Disease Virus O PanAsia - Pose A PDB

    ID: PDB:5NEM

    Description: O PanAsia VP1, Capsid protein, O PanAsia VP3, O PanAsia VP4, Integrin alpha-V, Integrin beta-6

    gene.name: ITGB6
  14. Molecular Phenotypes of Acute Kidney Injury in Kidney Transplants OmicsDI

    ID: E-GEOD-30718

    Date Released: 03-08-2012

    Description: ding many known epithelial injury molecules (e.g. ITGB6, LCN2), tissue remodeling molecules (e.g. VCAN), and inflammation molecules (S100A8, ITGB3). Many other genes also predict the phenotype, depending on statistical filtering rules, including AKI biomarkers as HAVCR1 and IL18. Most mouse orthologs of the top injury-repair transcripts were increased in published mouse AKI models. Pathway analysis of the injury-repair transcripts revealed similarities to cancer, development, and cell movement. The injury-repair transcript score AKI kidneys correlated with reduced function, future recovery, brain death, and need for dialysis, but not future graft loss. In contrast, histologic features of "acute tubular injury" did not correlate with function or with the molecular changes. Thus the in...

  15. Effect of acute and chronic social stress on hippocampal transcriptome in mice. OmicsDI

    ID: E-GEOD-59070

    Date Released: 07-15-2014

    Description: 2, Prlr, App, Cdh1, Col1A1, Clic6, Enpp2, Sostdc1,Itgb6, Mef2c, Spp1, and Zeb2. Obtained results suggest that stress may affect brain functions through the stress-induced dysfunction of the vascular system. Some of the key genes revealed by the review of published data participate both in the response to injury and in the mechanism of learning and memory. These genes may constitute a link between stress and stress-induced memory impairments. An important issue raised by our work is also the risk of tissue contamination with choroid plexus. Such contamination would result in consistent up- or down-regulation of genes, such as Ttr, Igf2, Igfbp2, ...

  16. Effect of acute and chronic social stress on hippocampal transcriptome in mice ArrayExpress

    ID: E-GEOD-59070

    Description: 2, Prlr, App, Cdh1, Col1A1, Clic6, Enpp2, Sostdc1,Itgb6, Mef2c, Spp1, and Zeb2. Obtained results suggest that stress may affect brain functions through the stress-induced dysfunction of the vascular system. Some of the key genes revealed by the review of published data participate both in the response to injury and in the mechanism of learning and memory. These genes may constitute a link between stress and stress-induced memory impairments. An important issue raised by our work is also the risk of tissue contamination with choroid plexus. Such contamination would result in consistent up- or down-regulation of genes, such as Ttr, Igf2, Igfbp2, ...

  17. Molecular Phenotypes of Acute Kidney Injury in Kidney Transplants ArrayExpress

    ID: E-GEOD-30718

    Description: ding many known epithelial injury molecules (e.g. ITGB6, LCN2), tissue remodeling molecules (e.g. VCAN), and inflammation molecules (S100A8, ITGB3). Many other genes also predict the phenotype, depending on statistical filtering rules, including AKI biomarkers as HAVCR1 and IL18. Most mouse orthologs of the top injury-repair transcripts were increased in published mouse AKI models. Pathway analysis of the injury-repair transcripts revealed similarities to cancer, development, and cell movement. The injury-repair transcript score AKI kidneys correlated with reduced function, future recovery, brain death, and need for dialysis, but not future graft loss. In contrast, histologic features of "acute tubular injury" did not correlate with function or with the molecular changes. Thus the injury-repai...

  18. Effect of acute and chronic social stress on hippocampal transcriptome in mice. BioProject

    ID: PRJNA254338

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: 2, Prlr, App, Cdh1, Col1A1, Clic6, Enpp2, Sostdc1,Itgb6, Mef2c, Spp1, and Zeb2. Obtained results suggest that stress may affect brain functions through the stress-induced dysfunction of the vascular system. Some of the key genes revealed by the review of published data participate both in the response to injury and in the mechanism of learning and memory. These genes may constitute a link between stress and stress-induced memory impairments. An important issue raised by our work is also the risk of tissue contamination with choroid plexus. Such contamination would result in consistent up- or down-regulation of genes, such as Ttr, Igf2, Igfbp2, ...
  19. Molecular Phenotypes of Acute Kidney Injury in Kidney Transplants BioProject

    ID: PRJNA144381

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ding many known epithelial injury molecules (e.g. ITGB6, LCN2), tissue remodeling molecules (e.g. VCAN), and inflammation molecules (S100A8, ITGB3). Many other genes also predict the phenotype, depending on statistical filtering rules, including AKI biomarkers as HAVCR1 and IL18. Most mouse orthologs of the top injury-repair transcripts were increased in published mouse AKI models. Pathway analysis of the injury-repair transcripts revealed similarities to cancer, development, and cell movement. The injury-repair transcript score AKI kidneys correlated with reduced function, future recovery, brain death, and need for dialysis, but not future graft loss. In contrast, histologic features of "acute tubular injury" did not correlate with function or with the molecular changes. Thus the injury-repai...
  20. Integrin beta-6 deficiency model of emphysema: alveolar macrophage GEO

    ID: geo.datasets:GDS1874

    Description: lysis of alveolar macrophages of integrin beta-6 (Itgb6) deficient animals treated with doxycycline. Itgb6 mutants develop emphysema. Effect of TGFbeta transgene ind...

    Types: Expression profiling by array

    Instrument: GPL1792


Displaying 20 of 20 results for "ITGB6"