ITGAV | bioCADDIE Data Discovery Index
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Displaying 20 of 23 results for "ITGAV"
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  1. VM2_BOTAL UniProt:Swiss-Prot

    ID: Q801Z4

    Description: ell attachment site May bind to alpha-V integrin (ITGAV) subunit May bind to alpha-V integrin (ITGAV) subunit May bind to metal ioncoordinated at the beta-3 integrin (ITGB3) subunit May bind to al...

  2. microRNA miR-142-3p induced expression changes in MDA-MB-231 breast cancer cells BioProject

    ID: PRJNA219097

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ndent regulation of the 3'-untranslated region of ITGAV and WASL. siRNA-mediated depletion of ITGAV andWASL resulted in a significant reduction of cellular invasiveness, highlighting the contribution of these factors to the miRNA-dependent invasion phenotype. While knockdown of WASL significantly reduced the number of membrane protrusions compared to controls, knockdown of ITGAV resulted in a decreased cell volume, indicating differential contributions of these factors to the miR-142-3p-induced phenotype. Our data identify WASL, ITGAV and several additional cytoskeleton associated molecules as novel invasion-promoting targets of miR-142-3p in breast cancer. Overall design: Biological triplicates of the human breast cancer cell line MDA-MB-231 were transiently transfected with miR-142-3p precursors (ABI) or a control miRNA. miRNA was prepared 72h after transfection, reverse transcribed, and analyzed by Affymetrix GeneChip Human Gene 1.0 ST arrays. Expression changes in selected targets significantly regulated in the Affymetrix screening were confirmed independently in miR-142-3p-transfected MDA-MB-231, MDA-MB-468 and MCF-7 cells by qPCR and Western blotting. Significantly regulated targets included WASL, ITGAV, RAC1, CFL2, IL6ST, PGRMC2, ROCK2, KLF4 and ADCY9....
  3. Expression profiling of Ebf2- and Ebf2- stromal cells in mouse bone marrow ArrayExpress

    ID: E-GEOD-51608

    Description: of Pdgfra, Pdgfrb, Sca1/Ly6a, Thy1 and Itga7 and Itgav, that have been suggested to be linked to MSCs. Nestin was mainly expressed in the Ebf2+ cells whereas it was hardly detectable in the Ebf2- cells. Altogether, molecularly, the Ebf2+ cells displayed features of a MSC. Ebf2 expression is not restricted to committed osteoblast progenitor cells but rather marks a multipotent mesenchymal progenitor cell population in adult mouse BM. These cells do not appear to be completely overlapping with the previous reported MSC populations. The findings provide new insights into the in vivo cellular identity and molecular properties of BM mesenchymal stem and progenitor cells. RNA was extracted from 1,000 or 2000 purified adult bone marrow cells using the RNAeasy microkit. RNA was labeled and amplified by dual amplification and hybridized to ...

  4. ITAV_CHICK UniProt:Swiss-Prot

    ID: P26008

    Description: Integrin alpha-V Integrin alpha-V heavy chain Integrin alpha-V light chain Extracellular Helical Cytoplasmic FG-GAP 1 FG-GAP 2 FG-GAP 3 FG-GAP 4 FG-GA...

    gene.name: ITGAV
  5. Expression profiling of Ebf2- and Ebf2- stromal cells in mouse bone marrow BioProject

    ID: PRJNA223943

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: of Pdgfra, Pdgfrb, Sca1/Ly6a, Thy1 and Itga7 and Itgav, that have been suggested to be linked to MSCs. Nestin was mainly expressed in the Ebf2+ cells whereas it was hardly detectable in the Ebf2- cells. Altogether, molecularly, the Ebf2+ cells displayed features of a MSC. Ebf2 expression is not restricted to committed osteoblast progenitor cells but rather marks a multipotent mesenchymal progenitor cell population in adult mouse BM. These cells do not appear to be completely overlapping with the previous reported MSC populations. The findings provide new insights into the in vivo cellular identity and molecular properties of BM mesenchymal stem and progenitor cells. Overall design: RNA was extracted from 1,000 or 2000 purified adult bone marrow cells using the RNAeasy microkit. RNA was labeled and amplified by dual amplification an...
  6. Crystal structure of integrin alpha V beta 6 head PDB

    ID: PDB:5FFG

    Description: Integrin alpha-V, Integrin beta-6

    gene.name: ITGAV, MSK8, VNRA
  7. CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN ALPHAVBETA3 PDB

    ID: PDB:1JV2

    Description: INTEGRIN, ALPHA V; PLATELET MEMBRANE GLYCOPROTEIN IIIA BETA SUBUNIT

  8. Integrin alpha V beta 6 in complex with pro-TGF-beta PDB

    ID: PDB:5FFO

    Description: Integrin alpha-V, Integrin beta-6, Transforming growth factor beta-1

    gene.name: ITGAV, MSK8, VNRA
  9. Localised Reconstruction of Integrin alpha v beta 6 bound to Foot and Mouth Disease Virus O1 Manisa - Pose B PDB

    ID: PDB:5NEU

    Description: O1 Manisa VP1, O1 Manisa VP2, Capsid protein, O1 Manisa VP4, Integrin alpha-V, Integrin beta-6

    gene.name: ITGAV, MSK8, VNRA
  10. Integrin AlphaVBeta3 ectodomain bound to an antagonistic tenth domain of Fibronectin PDB

    ID: PDB:4MMZ

    Description: Integrin alpha-V, Integrin beta-3, Fibronectin

    gene.name: alphav, ITGAV, MSK8, VNRA
  11. AlphaVBeta3 integrin in complex with monoclonal antibody FAB fragment. PDB

    ID: PDB:4O02

    Description: Integrin alpha-V, Integrin beta-3, 17E6 light chain, 17E6 heavy chain

    gene.name: ITGAV, MSK8, VNRA
  12. Structure of a GH39 Beta-xylosidase from Caulobacter crescentus PDB

    ID: PDB:4M29

    Description: Beta-xylosidase

    gene.name: Itgav, CC_2357
  13. Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin with the IAKGDWND motif PDB

    ID: PDB:4MMY

    Description: Integrin alpha-V, Integrin beta-3, Fibronectin

    gene.name: ITGAV, MSK8, VNRA
  14. Localised reconstruction of alpha v beta 6 bound to Foot and Mouth Disease Virus O PanAsia - Pose A prime PDB

    ID: PDB:5NER

    Description: Foot and mouth disease virus VP1, O PanAsia VP2, O PanAsia VP3, O PanAsia VP4, Integrin alpha-V, Integrin beta-6

    gene.name: ITGAV, MSK8, VNRA
  15. Re-refinement of alpha V beta 3 structure PDB

    ID: PDB:4G1M

    Description: Integrin alpha-V, Integrin beta-3

    gene.name: ITGAV, MSK8, VNRA
  16. Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin PDB

    ID: PDB:4MMX

    Description: Integrin alpha-V, Integrin beta-3, Fibronectin

    gene.name: alphav, ITGAV, MSK8, VNRA
  17. Localised Reconstruction of Integrin alpha v beta 6 bound to Foot and Mouth Disease Virus O1 Manisa - Pose A PDB

    ID: PDB:5NET

    Description: O1 Manisa VP1, O1 Manisa VP2, O1 Manisa VP3, O1 Manisa VP4, Integrin alpha-V, Integrin beta-6

    gene.name: ITGAV, MSK8, VNRA
  18. Localised reconstruction of alpha v beta 6 bound to Foot and Mouth Disease Virus O PanAsia - Pose A PDB

    ID: PDB:5NEM

    Description: O PanAsia VP1, Capsid protein, O PanAsia VP3, O PanAsia VP4, Integrin alpha-V, Integrin beta-6

    gene.name: ITGAV, MSK8, VNRA
  19. Crystal structure of a monomeric beta-xylosidase from Caulobacter crescentus CB15 PDB

    ID: PDB:4EKJ

    Description: Beta-xylosidase (E.C.3.2.1.37)

    gene.name: Itgav, CC_2357
  20. A novel adaptation of the integrin PSI domain revealed from its crystal structure PDB

    ID: PDB:1U8C

    Description: Integrin alpha-V, Integrin beta-3

    gene.name: ITGAV, VNRA

Displaying 20 of 23 results for "ITGAV"