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Displaying 20 of 140 results for "IRF1"
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  1. Expression data from primary adipocytes, ASCs, and ASC-adipocytes with or without IRF1 overexpression BioProject

    ID: PRJNA378722

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Genome-wide maps of chromatin state and abundance of transcription factors IRF1 and IRF4 in Th9 cells BioProject

    ID: PRJNA379395

    Keywords: Epigenomics

    Access Type: download

  3. Lung transcriptome from M. avium infected WT, IFNg-/- and IRF1-/- mice BioProject

    ID: PRJNA105897

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. Properties of STAT1 and IRF1 Enhancers and the Influence of SNPs BioProject

    ID: PRJNA369441

    Access Type: download

  5. Analysis of WT and IRF1-deficient Th9 cell transcriptomes in the presence of IFN-gamma BioProject

    ID: PRJNA379814

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Contribution of STAT3, IRF1 and PGAM5 to androgen response in prostate cancer cells BioProject

    ID: PRJNA322532

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. CIITA locus binding of H3ac, H4ac, STAT1, IRF1 antibodies in IFNg treated and untreated HeLa cells using nimblegen array BioProject

    ID: PRJNA108327

    Keywords: Epigenomics

    Access Type: download

  8. Critical role of the transcription factors IRF1 and BATF in preparing the chromatin landscape during Type 1 regulatory cell differentiation [RNA-seq] BioProject

    ID: PRJNA359392

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection OmicsDI

    ID: E-GEOD-66461

    Date Released: 03-06-2015

    Description: lear. Here we found that the transcription factor IRF1 was required for the activation of the AIM2 inflammasome during infection with the Francisella tularensis subspecies novicida (F. novicida), whereas engagement of the AIM2 inflammasome by mouse cytomegalovirus (MCMV) or transfected double-stranded DNA did not require IRF1. Infection of F. novicida detected ...

  10. Oncogenic Ras inhibits IRF1 to promote viral oncolysis BioProject

    ID: PRJNA213985

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. Identification of IFNg-regulated, IRF1-dependent genes in Shigella flexneri-infected mouse embryonic fibroblasts (MEFs) ArrayExpress

    ID: E-MTAB-713

    Description: periment was designed to identify IFNg-regulated, IRF1-dependent genes during infection with the intracellular pathogen Shigella flexneri. WT and Irf1-/- MEFs were stim...

  12. The macrophage IRF8-IRF1 regulome is required for protection against infections, and is associated with chronic inflammation (RNA-Seq) BioProject

    ID: PRJNA311950

    Keywords: Transcriptome or Gene expression

    Access Type: download

  13. Oncogenic Ras inhibits IRF1 to promote viral oncolysis ArrayExpress

    ID: E-GEOD-49469

    Description: fi47), we identified the IFN regulatory factor 1 (IRF1) binding site as the promoter region responsible for the regulation of transcription by MEK. MEK inhibition promoted transcription of the IFN-inducible genes in wild type mouse embryonic fibroblasts (MEFs), but not in IRF1−/− MEFs, showing that IRF1 is involved in MEK-mediated downregulation of IFN-inducible genes. Furthermore, IRF1 protein expression was lower in RasV12 cells compared with vector control NIH3T3 cells, but was restored to equivalent levels by inhibition of MEK. Similarly, the restoration of IRF1 expression by MEK inhibition was observed in human cancer cells. IRF1 re-expression in human cancer cells caused cells to become resistant to infection by the oncolytic vesicular stomatitis virus strain. Together, this work demonstrates that Ras/MEK activation in cancer cells downr...

  14. The macrophage IRF8-IRF1 regulome is required for protection against infections, and is associated with chronic inflammation (ChIP-Seq) BioProject

    ID: PRJNA311951

    Keywords: Epigenomics

    Access Type: download

  15. MOESM1 of Properties of STAT1 and IRF1 enhancers and the influence of SNPs Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3712804_D1

    Release Date: 03-10-2017

    Description: Additional file 1. Additional tables.

  16. 16MB binding of H3ac, H4ac, STAT1, IRF1 antibodies in IFNg treated and untreated HeLa cells using nimblegen array BioProject

    ID: PRJNA106917

    Keywords: Epigenomics

    Access Type: download

  17. Oncogenic Ras inhibits IRF1 to promote viral oncolysis OmicsDI

    ID: E-GEOD-49469

    Date Released: 11-28-2014

    Description: fi47), we identified the IFN regulatory factor 1 (IRF1) binding site as the promoter region responsible for the regulation of transcription by MEK. MEK inhibition promoted transcription of the IFN-inducible genes in wild type mouse embryonic fibroblasts (MEFs), but not in IRF1−/− MEFs, showing that IRF1 is involved in MEK-mediated downregulation of IFN-inducible genes. Furthermore, IRF1 protein expression was lower in RasV12 cells compared with vector control NIH3T3 cells, but was restored to equivalent levels by inhibition of MEK. Similarly, the restoration of IRF1 expression by MEK inhibition was observed in human cancer cells. IRF1 re-expression in human cancer cells caused cells to become resistant to infection by the oncolytic vesicular stomatitis virus strain. Together, this work demonstrates that Ras/MEK activation in cancer cells downr...

  18. The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection BioProject

    ID: PRJNA277018

    Keywords: Transcriptome or Gene expression

    Access Type: download

  19. Impact of IRF1 on transcriptome changes in Huh-7 human hepatoma cells and STAT1-deficient human fibroblasts BioProject

    ID: PRJNA136013

    Keywords: Transcriptome or Gene expression

    Access Type: download

  20. Transcription profiling of mouse wild type, IFNg-/- and IRF1-/- animals infected with from M. avium OmicsDI

    ID: E-GEOD-11809

    Date Released: 06-10-2011

    Description: necrosis in the lung which is dependent on IFNg. IRF1 is a transcription factor activated by IFNg signaling. The effect of IFNg and IRF1 on immunopathology and transcriptional changes in the lung were analysed using ...


Displaying 20 of 140 results for "IRF1"