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Displaying 9 of 9 results for "IL37"
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  1. Genome-wide immunity studies in the rabbit: transcriptome variations in PBMCs after in vitro stimulation by LPS or PMA/ionomycin ArrayExpress

    ID: E-GEOD-59263

    Description: increased transcription of IL6, IL1B, IL1A, IL36, IL37, TNF, CCL4 and SAA1 at T24. Surprisingly, we could not find an up-regulation of IL8 either at T4 or at T24. PMA/ionomycin induced a very early expression of Th1, Th2, iTreg, and Th17 responses by PBMCs at T4. The Th1 response was increased at T24 as shown by the increase of the transcription of IFNG and by contrast to other cytokines that significantly decreased from T4 to 24 (IL2, IL4, IL10, IL13, IL17A, CD69). The granulocyte-macrophage colony-stimulating factor (CSF2) was by far the most over-expressed gene at both T4 and T24 by comparison to mock-stimulated cells, confirming a major impact of PMA/ionomycin on cell growth and proliferation. A significant down-regulation of IL16 was observed at T4 and T24, in agreement with a role of IL16 in in PBMC apoptosis. Conclusion: We report new data on the responses of PBMCs to LPS and PMA/ionomycin fo...

  2. Crystal structure of Interleukin-37 PDB

    ID: PDB:5HN1

    Description: Interleukin-37

    gene.name: IL37, FIL1Z, IL1F7, IL1H4, IL1RP1
  3. Genome-wide immunity studies in the rabbit: transcriptome variations in PBMCs after in vitro stimulation by LPS or PMA/ionomycin BioProject

    ID: PRJNA254827

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: increased transcription of IL6, IL1B, IL1A, IL36, IL37, TNF, CCL4 and SAA1 at T24. Surprisingly, we could not find an up-regulation of IL8 either at T4 or at T24. PMA/ionomycin induced a very early expression of Th1, Th2, iTreg, and Th17 responses by PBMCs at T4. The Th1 response was increased at T24 as shown by the increase of the transcription of IFNG and by contrast to other cytokines that significantly decreased from T4 to 24 (IL2, IL4, IL10, IL13, IL17A, CD69). The granulocyte-macrophage colony-stimulating factor (CSF2) was by far the most over-expressed gene at both T4 and T24 by comparison to mock-stimulated cells, confirming a major impact of PMA/ionomycin on cell growth and proliferation. A significant down-regulation of IL16 was observed at T4 and T24, in agreement with a role of IL16 in in PBMC apoptosis. Conclusion: We report new data on the responses of PBMCs to LPS and PMA/ionomycin fo...
  4. IL-37 protects against obesity-induced inflammation and insulin resistance OmicsDI

    ID: E-GEOD-58952

    Date Released: 05-24-2015

    Description: e adipose tissue samples from wild type and human IL37-overexpressing transgenic mice fed a high fat diet for 16 weeks....

  5. IL-37 protects against obesity-induced inflammation and insulin resistance BioProject

    ID: PRJNA253964

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: e adipose tissue samples from wild type and human IL37-overexpressing transgenic mice fed a high fat diet for 16 weeks....
  6. IL-37 protects against obesity-induced inflammation and insulin resistance ArrayExpress

    ID: E-GEOD-58952

    Description: e adipose tissue samples from wild type and human IL37-overexpressing transgenic mice fed a high fat diet for 16 weeks....

  7. Microarray Profile of Measles Virus Nucleocapsid Protein (MVNP) Regulated Gene Expression in RANKL and M-CSF stimulated normal human bone marrow deriv... ArrayExpress

    ID: E-GEOD-29106

    Description: Paget’s disease of bone (PDB) is a chronic focal skeletal disorder that affects 2-3% of the population over the age of 60. PDB is inherited as an au...

  8. Genome-wide immunity studies in the rabbit: transcriptome variations in PBMCs after in vitro stimulation by LPS or PMA/ionomycin OmicsDI

    ID: E-GEOD-59263

    Date Released: 07-14-2014

    Description: increased transcription of IL6, IL1B, IL1A, IL36, IL37, TNF, CCL4 and SAA1 at T24. Surprisingly, we could not find an up-regulation of IL8 either at T4 or at T24. PMA/ionomycin induced a very early expression of Th1, Th2, iTreg, and Th17 responses by PBMCs at T4. The Th1 response was increased at T24 as shown by the increase of the transcription of IFNG and by contrast to other cytokines that significantly decreased from T4 to 24 (IL2, IL4, IL10, IL13, IL17A, CD69). The granulocyte-macrophage colony-stimulating factor (CSF2) was by far the most over-expressed gene at both T4 and T24 by comparison to mock-stimulated cells, confirming a major impact of PMA/ionomycin on cell growth and proliferation. A significant down-regulation of IL16 was observed at T4 and T24, in agreement with a role of IL16 in in PBMC apoptosis. Conclusion: We report new data on the responses of PBMCs to LPS and PMA/ionomycin fo...

  9. Microarray Profile of Measles Virus Nucleocapsid Protein (MVNP) Regulated Gene Expression in RANKL and M-CSF stimulated normal human bone marrow deriv... BioProject

    ID: PRJNA140367

    Keywords: Transcriptome or Gene expression

    Access Type: download


Displaying 9 of 9 results for "IL37"