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Displaying 20 of 1,378 results for "IDH2"
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  1. Mutations in IDH1 and IDH2 are associated with DNA hypermethylation in intrahepatic cholangiocarcinomas BioProject

    ID: PRJNA154939

    Keywords: Epigenomics

    Access Type: download

  2. Structure of IDH2 mutant R172K PDB

    ID: PDB:5SVN

    Description: Isocitrate dehydrogenase [NADP], mitochondrial (E.C.1.1.1.42)

  3. Mutations in IDH1 and IDH2 are associated with DNA hypermethylation in intrahepatic cholangiocarcinomas ArrayExpress

    ID: E-GEOD-32079

    Description: cinomas harboring mutations in the genes encoding isocitrate dehydrogenase, IDH1 and IDH2, with 28 intrahepatic cholangiocarcinomas without these mutations. We profiled these samples with the Illumina HumanMethylati...

  4. Crystal Structure of Human Mitochondrial Isocitrate Dehydrogenase (IDH2) R140Q Mutant Homodimer in Complex with AG-221 (Enasidenib) Inhibitor. PDB

    ID: PDB:5I96

    Description: Isocitrate dehydrogenase [NADP], mitochondrial (E.C.1.1.1.42)

  5. -associated mutations in Saccharomyces cerevisiae mitochondrial isocitrate dehydrogenase induce mitochondrial DNA instability... BioProject

    ID: PRJNA306764

    Keywords: raw sequence reads

    Access Type: download

  6. Structure of IDH2 mutant R140Q PDB

    ID: PDB:5SVO

    Description: Isocitrate dehydrogenase [NADP], mitochondrial (E.C.1.1.1.42)

  7. Induction of sarcomas by mutant IDH2 ArrayExpress

    ID: E-GEOD-50539

    Description: omas exhibit gain-of-function mutations in either isocitrate dehydrogenase 1 (IDH1) or IDH2. In this study, we performed genome-wide CpG methylation sequencing of chondrosarcoma biopsie...

  8. Induction of sarcomas by mutant IDH2 BioProject

    ID: PRJNA217989

    Keywords: Epigenomics

    Access Type: download

  9. Transcription profiling by array of human oligodendroglioma tumor samples with IDH1 and IDH2 mutations ArrayExpress

    ID: E-MEXP-3239

    Description: endroglioma. Sequencing for mutations of IDH1 and IDH2 was done. Gene expression was compared between IDH wildtype vs. mutant samples...

  10. AG-221 as an effective and on-target therapy in IDH2 mutant AML BioProject

    ID: PRJNA380630

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell haemangioma in Ollier disease and Maffucci syndrome ArrayExpress

    ID: E-GEOD-30844

    Description: xpression data of tumor samples with/without IDH1/2 mutations GSE31337: Methylation profiling of enchondromas with and without IDH1 mutations Refer to individual Series...

  12. IDH2 mutation induced histone and DNA hypermethylation is progressively reversed by small molecule inhibition BioProject

    ID: PRJNA222799

    Keywords: Epigenomics

    Access Type: download

  13. D-2-Hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice ArrayExpress

    ID: E-GEOD-54838

    Description: Mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2) have been discovered in several ...

  14. The IDH2 mutation cooperates with the NPM1 mutation to activate Hoxa9/Meis1 and hypoxia pathways in acute myeloid leukemia (MeDip-seq) BioProject

    ID: PRJNA268509

    Keywords: Epigenomics

    Access Type: download

  15. DNA hypermethylation in intrahepatic cholangiocarcinomas and glioblastomas ArrayExpress

    ID: E-GEOD-32286

    Description: ng subset Series: GSE32079: Mutations in IDH1 and IDH2 are associated with DNA hypermethylation in intrahepatic cholangiocarcinomas GSE32283: Mutations in IDH1 are associated with DNA hypermethylation in glioblastomas Refer ...

  16. D-2-Hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice BioProject

    ID: PRJNA237792

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. c signaling and reverse epigenetic dysfunction in IDH2- and TET2-mutant acute myeloid leukemia... BioProject

    ID: PRJNA313219

    Access Type: download

  18. Human SIRT5 bound to Succ-IDH2 and Carba-NAD PDB

    ID: PDB:4G1C

    Description: NAD-dependent protein deacylase sirtuin-5, mitochondrial (E.C.3.5.1.-), Succinylated IDH2 peptide

  19. IDH2 mutation induced histone and DNA hypermethylation is progressively reversed by small molecule inhibition ArrayExpress

    ID: E-GEOD-51352

    Description: Mutations of IDH1 (R132) and IDH2 (R172 and R140), which produce an oncometabolite 2-hydroxyglutarate (2HG), have been identified in several ...

  20. Sequence_alignments Dryad

    DateIssued: 12-10-2014

    Description: Sequence alignments of Pogonus chalcesu mitochondrial NADP+-dependent isocitrate dehydrogenase (mtIdh), cytoplasmi...


Displaying 20 of 1,378 results for "IDH2"