HTRA3 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 15 of 15 results for "HTRA3"
i
  1. Serine Protease HtrA3, mutationally inactivated PDB

    ID: PDB:4RI0

    Description: Serine protease HTRA3 (E.C.3.4.21.-)

  2. Crystal Structure of the HtrA3 PDZ Domain Bound to a Phage-Derived Ligand (FGRWV) PDB

    ID: PDB:2P3W

    Description: Probable serine protease HTRA3 (E.C.3.4.21.-)

  3. Influence of Gross Ovarian Stage on Transcript Profiles in Fathead Minnow (Pimephales promelas) Ovary Tissue ArrayExpress

    ID: E-GEOD-18254

    Description: genes identified in the study, targets including HtrA serine peptidase 3 (htra3), tissue inhibitor of metalloproteinase 3 (timp3), aquaporin 8 (aqp8), transgelin 2 like (tagln2), Nedd4 family interacting protein 2 (ndfip2), chemokine ligand 12a (cxcl12a), midkine related growth factor (mdka), and jagged 1b (jag 1b) exhibited responses and functional properties that support them as candidate molecular markers of significant shift in gross ovarian stage. Overall, results of this study provide insights into background variation in ovary transcript profiles that should aid and enhance the interpretation of toxicogenomic data generated in experiments conducted with small, asynchronous spawning fish species. Relative abundance of approximately 15,000 RNA transcripts in 26 ovary samples and 4 expelled oocyte (egg) samples, representing the five different histoclasses defined for the present study, was evaluated using fathead minnow oligonucleotide microarrays. Fathead minnow 15,000 gene arrays were purchased from Agilent (Palo Alto, CA, USA). The Agilent one-color microarray...

  4. Influence of Gross Ovarian Stage on Transcript Profiles in Fathead Minnow (Pimephales promelas) Ovary Tissue BioProject

    ID: PRJNA119595

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: genes identified in the study, targets including HtrA serine peptidase 3 (htra3), tissue inhibitor of metalloproteinase 3 (timp3), aquaporin 8 (aqp8), transgelin 2 like (tagln2), Nedd4 family interacting protein 2 (ndfip2), chemokine ligand 12a (cxcl12a), midkine related growth factor (mdka), and jagged 1b (jag 1b) exhibited responses and functional properties that support them as candidate molecular markers of significant shift in gross ovarian stage. Overall, results of this study provide insights into background variation in ovary transcript profiles that should aid and enhance the interpretation of toxicogenomic data generated in experiments conducted with small, asynchronous spawning fish species. Overall design: Relative abundance of approximately 15,000 RNA transcripts in 26 ovary samples and 4 expelled oocyte (egg) samples, representing the five different histoclasses defined for the present study, was evaluated using fathead minnow oligonucleotide microarrays. Fathead minnow 15,000 gene arrays were purchased from Agilent (Palo Alto, CA, USA). The Agilent one-co...
  5. Influence of Gross Ovarian Stage on Transcript Profiles in Fathead Minnow (Pimephales promelas) Ovary Tissue OmicsDI

    ID: E-GEOD-18254

    Date Released: 06-27-2012

    Description: genes identified in the study, targets including HtrA serine peptidase 3 (htra3), tissue inhibitor of metalloproteinase 3 (timp3), aquaporin 8 (aqp8), transgelin 2 like (tagln2), Nedd4 family interacting protein 2 (ndfip2), chemokine ligand 12a (cxcl12a), midkine related growth factor (mdka), and jagged 1b (jag 1b) exhibited responses and functional properties that support them as candidate molecular markers of significant shift in gross ovarian stage. Overall, results of this study provide insights into background variation in ovary transcript profiles that should aid and enhance the interpretation of toxicogenomic data generated in experiments conducted with small, asynchronous spawning fish species. Relative abundance of approximately 15,000 RNA transcripts in 26 ovary samples and 4 expelled oocyte (egg) samples, representing the five different histoclasses defined for the present study, was evaluated using fathead minnow oligonucleotide microarrays. Fathead minnow 15,000 gene arrays were purchased from Agilent (Palo Alto, CA, USA). The Agilent one-color microarray...

  6. HtrA1 bound to an optimized peptide: NMR assignment of PDZ domain and ligand resonances PDB

    ID: PDB:2JOA

    Description: Serine protease HTRA1 (E.C.3.4.21.-), Peptide H1-C1

  7. Comparative Genome Analysis of Ureaplasma parvum Clinical Isolates ArrayExpress

    ID: E-GEOD-5378

    Description: as a causative agent of nongonococcal urethritis, pregnancy complications and prenatal infections. Ureaplasma may also cause central nervous system infections and affect the lower respiratory tract of newborn babies. However, Ureaplasma spp. have also been detected in the urogenital tracts of clinically ...

  8. Comparative Genome Analysis of Ureaplasma parvum Clinical Isolates BioProject

    ID: PRJNA96283

    Keywords: Variation

    Access Type: download

    dataset.description: as a causative agent of nongonococcal urethritis, pregnancy complications and prenatal infections. Ureaplasma may also cause central nervous system infections and affect the lower respiratory tract of newborn babies. However, Ureaplasma spp. have also been detected in the urogenital tracts of clinically ...
  9. Adult and neonatal astrocytes exhibit diverse gene expression profiles during exposure to beta amyloid ex vivo ArrayExpress

    ID: E-GEOD-29317

    Description: alysis confirmed the significant up-regulation of HtrA serine peptidase 1 (Htra1), metallopeptidase 9 (Mmp9), phosphate regulating gene with homologies to endopeptidases on the X chromosome (Phex) and scavenger receptor class A, member 5 (Scara5) in adult astrocytes, whereas neonatal astrocytes up-regulated Mmp9 and down-regulated genes related to cholesterol transport and synthesis: apolipoprotein E (Apoe), 24-dehydrocholesterol reductase (Dhcr24) and 3-hydroxy-3-methylglutaryl-CoA synthase 1 (Hmgcs1). These findings brought out novel genes which expression is altered during Aβ clearance in adult and neonatal astrocytes ex vivo. Astrocyte cultures: For the adult astrocyte cultures, hippoc...

  10. KRA92_PANTR UniProt:Swiss-Prot

    ID: A5A6P5

    Description: Keratin-associated protein 9-2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 17 X 5 AA repeats of C-C-[RQVSGE]-[SPTQ]-[TASP]...

  11. Adult and neonatal astrocytes exhibit diverse gene expression profiles during exposure to beta amyloid ex vivo OmicsDI

    ID: E-GEOD-29317

    Date Released: 07-23-2012

    Description: alysis confirmed the significant up-regulation of HtrA serine peptidase 1 (Htra1), metallopeptidase 9 (Mmp9), phosphate regulating gene with homologies to endopeptidases on the X chromosome (Phex) and scavenger receptor class A, member 5 (Scara5) in adult astrocytes, whereas neonatal astrocytes up-regulated Mmp9 and down-regulated genes related to cholesterol transport and synthesis: apolipoprotein E (Apoe), 24-dehydrocholesterol reductase (Dhcr24) and 3-hydroxy-3-methylglutaryl-CoA synthase 1 (Hmgcs1). These findings brought out novel genes which expression is altered during Aβ clearance in adult and neonatal astrocytes ex vivo. Astrocyte cultures: For the adult astrocyte cultures, hippoc...

  12. Adult and neonatal astrocytes exhibit diverse gene expression profiles during exposure to beta amyloid ex vivo BioProject

    ID: PRJNA141617

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: alysis confirmed the significant up-regulation of HtrA serine peptidase 1 (Htra1), metallopeptidase 9 (Mmp9), phosphate regulating gene with homologies to endopeptidases on the X chromosome (Phex) and scavenger receptor class A, member 5 (Scara5) in adult astrocytes, whereas neonatal astrocytes up-regulated Mmp9 and down-regulated genes related to cholesterol transport and synthesis: apolipoprotein E (Apoe), 24-dehydrocholesterol reductase (Dhcr24) and 3-hydroxy-3-methylglutaryl-CoA synthase 1 (Hmgcs1). These findings brought out novel genes which expression is altered during Aβ clearance in adult and neonatal astrocytes ex vivo. Overall design: Astrocyte cultures: For the adult astrocyte ...
  13. Cell cycle dependent phosphorylation of transmembrane proteins on the Theileria annulata schizont surface OmicsDI

    ID: PXD000899

    Date Released: 12-12-2014

    Description: hosphorylated threonine (p-Thr and p-Thr-Pro) and serine (p-Ser) epitopes on the schizont during host cell cycle progression, revealing extensive schizont surface phosphorylation during host cell interphase. Further, we isolated schizonts from infected macrophages following synchronisation in S-phase or mitosis, and used mass spectrometry to detect phosphorylated schizont proteins. In total, 65 phosphorylated Theileria proteins were detected, 15 of which are potentially secreted or expressed on the surface of the schizont and thus mayight be targets forof host cell kinases. In particular, we describe the cell-cycle stage phosphorylation of two T. annulata surface expressed proteins, TaSP and p104. Phospho-peptides of both proteins were significantly more abundant in schizonts purified from S-phase cells....

  14. Evaluation of the Impact of System-Wide Drug Testing in Multnomah County, Oregon, 1991-1992 Dataverse

    Description: isions: the Pretrial Release Supervision Program (PRSP) and the probation and parole program. The pretrial division was chosen because it was the first opportunity for the criminal justice system to supervise and control the drug use of potential DTE clients. The probation and parole program was selected for three reasons: it was the largest component of the DTE program, it linked the pretrial and post-sentence DTE programs, and the experience of this program could be readily applied to the development of other such programs in other jurisdictions. The programs were evaluated using administrative data collected by corrections technicians, case managers, probation and parole officers, and the DTE central office. Part 1 (Pretrial Data) variables include dates of entry into and exit from the program, number of drug tests, number of positive test...

    Person: Cavanagh, David P.

    Release Date: 04-08-2015

  15. Evaluation of the Impact of System-Wide Drug Testing in Multnomah County, Oregon, 1991-1992 ICPSR

    ID: doi:10.3886/ICPSR02589.v1

    Description: isions: the Pretrial Release Supervision Program (PRSP) and the probation and parole program. The pretrial division was chosen because it was the first opportunity for the criminal justice system to supervise and control the drug use of potential DTE clients. The probation and parole program was selected for three reasons: it was the largest component of the DTE program, it linked the pretrial and post-sentence DTE programs, and the experience of this program could be readily applied to the development of other such programs in other jurisdictions. The programs were evaluated using administrative data collected by corrections technicians, case managers, probation and parole officers, and the DTE central office. Part 1 (Pretrial Data) variables include dates of entry into and exit from the program, number of drug tests, number of positive te...

    Creators: Cavanagh, David P.


Displaying 15 of 15 results for "HTRA3"