HTR2B | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 13 of 13 results for "HTR2B"
i
  1. ion of the human 5-Hydroxytryptamine receptor 2B (HTR2B) gene is under the regulatory influence of the transcription factors NFI and RUNX1 in human uveal melanoma... BioProject

    ID: PRJNA342951

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Gene expression analysis in the absence of Creb in Pomc-expressing neurons of the hypothalamus BioProject

    ID: PRJNA135509

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: te in mice following its binding to the Htr1a and Htr2b receptors in arcuate neurons of the hypothalamus. In this study, we identified that CREB is the transcriptional effector of brain-derived serotonin control of app...
  3. Crystal structure of the chimeric protein of 5-HT2B-BRIL in complex with ergotamine PDB

    ID: PDB:4IB4

    Description: Human 5-HT2B receptor_BRIL chimera

    gene.name: HTR2B
  4. Crystal structure of the LSD-bound 5-HT2B receptor PDB

    ID: PDB:5TVN

    Description: 5-hydroxytryptamine receptor 2B,Soluble cytochrome b562,5-hydroxytryptamine receptor 2B

    gene.name: HTR2B
  5. Gene expression analysis in the absence of Creb in Pomc-expressing neurons of the hypothalamus ArrayExpress

    ID: E-GEOD-26037

    Description: te in mice following its binding to the Htr1a and Htr2b receptors in arcuate neurons of the hypothalamus. In this study, we identified that CREB is the transcriptional effector of brain-derived serotonin control of app...

  6. Crystal structure of the 5-HT2B receptor solved using serial femtosecond crystallography in lipidic cubic phase. PDB

    ID: PDB:4NC3

    Description: Chimera protein of human 5-hydroxytryptamine receptor 2B and E. Coli soluble cytochrome b562

    gene.name: HTR2B
  7. RNA-seq of pancreatic islets from pregnant mice ArrayExpress

    ID: E-GEOD-21860

    Description: . Expression of the Gq-linked serotonin receptor Htr2b in maternal islets increased during pregnancy and normalized just prior to parturition, while expression of the Gi-linked receptor Htr1d increased at the end of pregnancy and postpartum. Blocking Htr2b signaling in pregnant mice also blocked beta-cell expansion and caused glucose intolerance. These studies reveal an integrated signaling pathway linking beta-cell mass to anticipated insulin need during pregnancy. Modulators of this pathway, including medications and diet, may affect the risk of gestational diabetes. Analysis of poly(A)+ RNA from 3 biological replicates of pancreatic islets isolated from normal female and pregnant female mice...

  8. RNA-seq of pancreatic islets from pregnant mice OmicsDI

    ID: E-GEOD-21860

    Date Released: 04-30-2015

    Description: . Expression of the Gq-linked serotonin receptor Htr2b in maternal islets increased during pregnancy and normalized just prior to parturition, while expression of the Gi-linked receptor Htr1d increased at the end of pregnancy and postpartum. Blocking Htr2b signaling in pregnant mice also blocked beta-cell expansion and caused glucose intolerance. These studies reveal an integrated signaling pathway linking beta-cell mass to anticipated insulin need during pregnancy. Modulators of this pathway, including medications and diet, may affect the risk of gestational diabetes. Analysis of poly(A)+ RNA from 3 biological replicates of pancreatic islets isolated from normal female and pregnant female mice...

  9. 5HT2B_CAVPO UniProt:Swiss-Prot

    ID: P97267

    Description: 5-hydroxytryptamine receptor 2B Extracellular Helical; Name=7 Cytoplasmic NPxxY motif; important for ligand-induced conformation changes and signaling...

    gene.name: HTR2B
  10. 5HT2B_PIG UniProt:Swiss-Prot

    ID: Q29005

    Description: 5-hydroxytryptamine receptor 2B Extracellular Helical; Name=3 Cytoplasmic Helical; Name=4 Agonist binding DRY motif; important for ligand-induced conf...

    gene.name: HTR2B
  11. RNA-seq of pancreatic islets isolated from normal female and pregnant female mice BioProject

    ID: PRJNA127041

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: . Expression of the Gq-linked serotonin receptor Htr2b in maternal islets increased during pregnancy and normalized just prior to parturition, while expression of the Gi-linked receptor Htr1d increased at the end of pregnancy and postpartum. Blocking Htr2b signaling in pregnant mice also blocked beta-cell expansion and caused glucose intolerance. These studies reveal an integrated signaling pathway linking beta-cell mass to anticipated insulin need during pregnancy. Modulators of this pathway, including medications and diet, may affect the risk of gestational diabetes. Overall design: Analysis of poly(A)+ RNA from 3 biological replicates of pancreatic islets isolated from normal female and pregnant female mice...
  12. Gene expression analysis in the absence of Creb in Pomc-expressing neurons of the hypothalamus OmicsDI

    ID: E-GEOD-26037

    Date Released: 06-10-2011

    Description: te in mice following its binding to the Htr1a and Htr2b receptors in arcuate neurons of the hypothalamus. In this study, we identified that CREB is the transcriptional effector of brain-derived serotonin control of app...

  13. Morphological and molecular characterization of human dermal lymphatic collectors BioProject

    ID: PRJNA344487

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: P2RY12, 13, and 14; 5-hydroxytryptamine receptors HTR2B, and 3C; and adrenoceptors α2A,B,C. Our studies represent the first comprehensive characterization of human epifascial lymphatic collectors, as a prerequisite for diagnosis and therapy. Overall design: The transcriptome of 6 different normal human lymphatic collectors (Lyko1, Lyko 4-12, Lyko 5, Lyko12, Lyko13, Lyko26) from the dermis of the thigh of women between 44 and 61 years of age was compared to cultures of human dermal lymphatic endothelial cells (LEC1, LEC2, HD-LEC9A) and a mixture of 3 different human dermal blood endothelial cells (HD-BEC-CA) to identify potential drug targets in the media of the collectors....

Displaying 13 of 13 results for "HTR2B"