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Displaying 19 of 19 results for "HTR2A"
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  1. the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3618554_D11

    Release Date: 12-15-2016

    Description: Mouse Htr2a-AS1 exons and coordinates. (XLSX 12 kb)

  2. the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3618554_D8

    Release Date: 12-15-2016

    Description: Mouse Htr2a exons and coordinates. (XLSX 12 kb)

  3. the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3618554_D7

    Release Date: 12-15-2016

    Description: Predicted splicing proteins bound to human HTR2A rs6313 alleles. (XLSX 11 kb)

  4. the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3618554_D10

    Release Date: 12-15-2016

    Description: Splice junctions and counts for human HTR2A-AS1. (XLSX 12 kb)

  5. the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3618554_D14

    Release Date: 12-15-2016

    Description: Predicted HTR2A-AS1 transcripts and open reading frames. (XLSX 13 kb)

  6. the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3618554_D12

    Release Date: 12-15-2016

    Description: Mapping statistics for human DLPFC RNA-Seq samples (XLSX 22 kb)

  7. Tracheal Occlusion Modulates the Gene Expression Profile of the Medial Thalamus in Anesthetized Rats ArrayExpress

    ID: E-GEOD-25153

    Description: ted. A significant up-regulation of the serotonin HTR2A receptor and significant down-regulation of the dopamine DRD1 receptor genes were found. A pathway analysis was performed targeting serotonin and dopamine receptor pathways. The mitogen activated protein kinase 1 (MAPK1) gene was significantly down-regulated. MAPK1 is an inhibitory regulator of the serotonin HTR2A receptor and facilitatory regulator for the dopamine DRD1 receptor. Down-regulation of MAPK1 may be related to the 2-fold up-regulation of HTR2A and 2-fold down-regulation of DRD1 suggesting an interaction in the medial thalamus serotonin-dopamine pathway elicited by airway obstruction. These results demonstrate an immediate change in gene expression in thalamic arousal-fear-anxiety-motivation related serotonin and dopamine receptors in response to airway obstruction. The results support the hypothesis that the thalamus is a component in the respiratory mechanosensory neural pathway. Four experimental animals that received tracheal occlusions and four surgical control animals were used. A reference design was used to compare all samples....

  8. Tracheal Occlusion Modulates the Gene Expression Profile of the Medial Thalamus in Anesthetized Rats BioProject

    ID: PRJNA134337

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ted. A significant up-regulation of the serotonin HTR2A receptor and significant down-regulation of the dopamine DRD1 receptor genes were found. A pathway analysis was performed targeting serotonin and dopamine receptor pathways. The mitogen activated protein kinase 1 (MAPK1) gene was significantly down-regulated. MAPK1 is an inhibitory regulator of the serotonin HTR2A receptor and facilitatory regulator for the dopamine DRD1 receptor. Down-regulation of MAPK1 may be related to the 2-fold up-regulation of HTR2A and 2-fold down-regulation of DRD1 suggesting an interaction in the medial thalamus serotonin-dopamine pathway elicited by airway obstruction. These results demonstrate an immediate change in gene expression in thalamic arousal-fear-anxiety-motivation related serotonin and dopamine receptors in response to airway obstruction. The results support the hypothesis that the thalamus is a component in the respiratory mechanosensory neural pathway. Overall design: Four experimental animals that received tracheal occlusions and four surgical control animals were used. A reference design was used to compare all samples....
  9. Tracheal Occlusion Modulates the Gene Expression Profile of the Medial Thalamus in Anesthetized Rats OmicsDI

    ID: E-GEOD-25153

    Date Released: 05-02-2014

    Description: ted. A significant up-regulation of the serotonin HTR2A receptor and significant down-regulation of the dopamine DRD1 receptor genes were found. A pathway analysis was performed targeting serotonin and dopamine receptor pathways. The mitogen activated protein kinase 1 (MAPK1) gene was significantly down-regulated. MAPK1 is an inhibitory regulator of the serotonin HTR2A receptor and facilitatory regulator for the dopamine DRD1 receptor. Down-regulation of MAPK1 may be related to the 2-fold up-regulation of HTR2A and 2-fold down-regulation of DRD1 suggesting an interaction in the medial thalamus serotonin-dopamine pathway elicited by airway obstruction. These results demonstrate an immediate change in gene expression in thalamic arousal-fear-anxiety-motivation related serotonin and dopamine receptors in response to airway obstruction. The results support the hypothesis that the thalamus is a component in the respiratory mechanosensory neural pathway. Four experimental animals that received tracheal occlusions and four surgical control animals were used. A reference design was used to compare all samples....

  10. Tracheal occlusion conditioning in conscious rats modulates gene expression profile of medial thalamus ArrayExpress

    ID: E-GEOD-25152

    Description: nificant down-regulation of GAD1, GAD2 and HTR1A, HTR2A genes. CCK, PRKCG, mGluR4, and KCJN9 genes were significantly up-regulated. Some of these genes have been associated with anxiety and depression, while others have been shown to play a role in switching between tonic and burst firing modes in the thalamus and thus may be involved in gating of the respiratory stimuli. Furthermore, gene ontology and pathway analysis showed a significant modulation of learning and memory pathways. These results support the hypothesis that the medial thalamus is involved in the respiratory sensory neural pathway due to the state change of its gene expression profile following repeated tracheal occlusions. Four experimental animals that received tracheal occlusions and four surgical control animals were used. A reference design was used to compare all samples....

  11. 5HT2A_CRIGR UniProt:Swiss-Prot

    ID: P18599

    Description: 5-hydroxytryptamine receptor 2A Extracellular Helical; Name=1 Cytoplasmic Helical; Name=2 Extracellular Helical; Name=3 Cytoplasmic Helical; Name=4 Ex...

    gene.name: HTR2A
  12. 5HT2A_MACMU UniProt:Swiss-Prot

    ID: P50128

    Description: 5-hydroxytryptamine receptor 2A Extracellular Helical; Name=1 Cytoplasmic Helical; Name=2 Extracellular Helical; Name=3 Cytoplasmic Helical; Name=4 Ex...

    gene.name: HTR2A
  13. Tracheal occlusion conditioning in conscious rats modulates gene expression profile of medial thalamus BioProject

    ID: PRJNA134491

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: nificant down-regulation of GAD1, GAD2 and HTR1A, HTR2A genes. CCK, PRKCG, mGluR4, and KCJN9 genes were significantly up-regulated. Some of these genes have been associated with anxiety and depression, while others have been shown to play a role in switching between tonic and burst firing modes in the thalamus and thus may be involved in gating of the respiratory stimuli. Furthermore, gene ontology and pathway analysis showed a significant modulation of learning and memory pathways. These results support the hypothesis that the medial thalamus is involved in the respiratory sensory neural pathway due to the state change of its gene expression profile following repeated tracheal occlusions. Overall design: Four experimental animals that received tracheal occlusions and four surgical control animals were used. A reference design was used to compare all samples....
  14. GRM2_MOUSE UniProt:Swiss-Prot

    ID: Q14BI2

    Description: Glutamate binding Important for interaction with HTR2A Glutamate Glutamate Glutamate Glutamate N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...)...

  15. 5HT2A_CAVPO UniProt:Swiss-Prot

    ID: P35382

    Description: 5-hydroxytryptamine receptor 2A Extracellular Helical; Name=3 Cytoplasmic Helical; Name=4 Extracellular Helical; Name=5 Cytoplasmic Helical; Name=6 Ex...

    gene.name: HTR2A
  16. GRM2_RAT UniProt:Swiss-Prot

    ID: P31421

    Description: Glutamate binding Important for interaction with HTR2A Glutamate Glutamate Glutamate Glutamate N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...)...

  17. Tracheal occlusion conditioning in conscious rats modulates gene expression profile of medial thalamus OmicsDI

    ID: E-GEOD-25152

    Date Released: 06-10-2011

    Description: nificant down-regulation of GAD1, GAD2 and HTR1A, HTR2A genes. CCK, PRKCG, mGluR4, and KCJN9 genes were significantly up-regulated. Some of these genes have been associated with anxiety and depression, while others have been shown to play a role in switching between tonic and burst firing modes in the thalamus and thus may be involved in gating of the respiratory stimuli. Furthermore, gene ontology and pathway analysis showed a significant modulation of learning and memory pathways. These results support the hypothesis that the medial thalamus is involved in the respiratory sensory neural pathway due to the state change of its gene expression profile following repeated tracheal occlusions. Four experimental animals that received tracheal occlusions and four surgical control animals were used. A reference design was used to compare all samples....

  18. Effect of Maternal Separation on DOI-induced transcriptome ArrayExpress

    ID: E-GEOD-23728

    Description: Depression is a heterogeneous disorder characterized by a wide range of symptoms, including but not restricted to increased anxiety-like behavior, alt...

  19. Effect of Maternal Separation on DOI-induced transcriptome BioProject

    ID: PRJNA130675

    Keywords: Transcriptome or Gene expression

    Access Type: download


Displaying 19 of 19 results for "HTR2A"