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Displaying 17 of 17 results for "HOXC8"
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  1. e stem cells (ADSCs) transduced with homeobox C8 (Hoxc8) or control vector, followed by treatment with adipogenic-induction media for 14 days... ArrayExpress

    ID: E-GEOD-22429

    Description: inguishing the two fat types. Among 39 Hox genes, Hoxc8 is highly enriched in undifferentiated adipose tissue stem cells (ADSCs) and down-regulated in differentiated adipocytes. Forced expression of Hoxc8 suppressed adipocyte differentiation of ADSCs. Using microarrays, we investigated the effect of Hoxc8 overexpression on global transcripts in ADSCs. We compared among four groups: untreated ADSCs, adipogenic induction media (MDI)-treated ADSCs, MDI...

  2. e stem cells (ADSCs) transduced with homeobox C8 (Hoxc8) or control vector, followed by treatment with adipogenic-induction media for 14 days... OmicsDI

    ID: E-GEOD-22429

    Date Released: 05-01-2014

    Description: inguishing the two fat types. Among 39 Hox genes, Hoxc8 is highly enriched in undifferentiated adipose tissue stem cells (ADSCs) and down-regulated in differentiated adipocytes. Forced expression of Hoxc8 suppressed adipocyte differentiation of ADSCs. Using microarrays, we investigated the effect of Hoxc8 overexpression on global transcripts in ADSCs. We compared among four groups: untreated ADSCs, adipogenic induction media (MDI)-treated ADSCs, MDI...

  3. e stem cells (ADSCs) transduced with homeobox C8 (Hoxc8) or control vector, followed by treatment with adipogenic-induction media for 14 days... BioProject

    ID: PRJNA128553

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. Overexpression of Hoxc8 transcription factor alters transcriptional profiles in mouse chondrocytes at E18.5 BioProject

    ID: PRJNA123735

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Microarray analysis of defective cartilage in Hoxc8- and Hoxd4-transgenic mice ArrayExpress

    ID: E-GEOD-19002

    Description: chondrocytes at E18.5 GSE18992: Overexpression of Hoxc8 transcription factor alters transcriptional profiles in mouse chondrocytes at E18.5!Series_overall_design = Refer to individual Series Refer to individual Series...

  6. Microarray analysis of defective cartilage in Hoxc8- and Hoxd4-transgenic mice OmicsDI

    ID: E-GEOD-19002

    Date Released: 06-10-2011

    Description: chondrocytes at E18.5 GSE18992: Overexpression of Hoxc8 transcription factor alters transcriptional profiles in mouse chondrocytes at E18.5!Series_overall_design = Refer to individual Series Refer to individual Series...

  7. Overexpression of Hoxc8 transcription factor alters transcriptional profiles in mouse chondrocytes at E18.5 ArrayExpress

    ID: E-GEOD-18992

    Description: iation. In transgenic mice with overexpression of Hoxc8 during cartilage development, we observed severe defects, namely physical instability of cartilage, accumulation of immature chondrocytes, and decreased maturation to hypertrophy. To define the molecular basis underlying these defects, we performed ge...

  8. Overexpression of Hoxc8 transcription factor alters transcriptional profiles in mouse chondrocytes at E18.5 OmicsDI

    ID: E-GEOD-18992

    Date Released: 06-10-2011

    Description: iation. In transgenic mice with overexpression of Hoxc8 during cartilage development, we observed severe defects, namely physical instability of cartilage, accumulation of immature chondrocytes, and decreased maturation to hypertrophy. To define the molecular basis underlying these defects, we performed ge...

  9. HOX genes: potential candidates furthering the development of larynx squamous cell carcinoma. OmicsDI

    ID: E-GEOD-59102

    Date Released: 01-02-2015

    Description: ession data, ROC curve analysis yet revealed that HOXC8 and HOXD11 genes are related to the tumor differentiation degree and regional lymph node metastasis, respectively. From siRNA assay, we found that HOXC8 and HOXD11 genes are essential for the expansion of FADU cell colonies. Our findings strongly suggest that members of the HOX family might be associated with the development of LSCC. Twenty nine cancer samples and thirteen margin samples were collected from patients undergoing surgical ablation of LSCC according to Ethic Committee guideline and patient pre-informed signed consents. Whole human genome microarray analysis was applied to investigate new genetic targets in LSCC....

  10. Genes modulated by rhBMP2 and rhBMP7 during osteoblastic differentiation of C2C12 cells ArrayExpress

    ID: E-GEOD-23783

    Description: . Moreover, we identified some new genes, such as Hoxc8, Glis1, Glis3, Ecsit, LrP6, Dvl1, Grn, BMP1, Ltbp2, Plod1, Htra1 and IGFBP-rP10, to be upregulated by both rhBMPs. Total RNA from mouse pre-myoblastic and pre-osteoblastic C2C12 cell line, after 12h of treatment with rhBMP2 and rhBMP7, was hybridized to a microarray and analyzed....

  11. HOX genes: potential candidates furthering the development of larynx squamous cell carcinoma ArrayExpress

    ID: E-GEOD-59102

    Description: ession data, ROC curve analysis yet revealed that HOXC8 and HOXD11 genes are related to the tumor differentiation degree and regional lymph node metastasis, respectively. From siRNA assay, we found that HOXC8 and HOXD11 genes are essential for the expansion of FADU cell colonies. Our findings strongly suggest that members of the HOX family might be associated with the development of LSCC. Twenty nine cancer samples and thirteen margin samples were collected from patients undergoing surgical ablation of LSCC according to Ethic Committee guideline and patient pre-informed signed consents. Whole human genome microarray analysis was applied to investigate new genetic targets in LSCC....

  12. HOX genes: potential candidates furthering the development of larynx squamous cell carcinoma. BioProject

    ID: PRJNA254422

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ession data, ROC curve analysis yet revealed that HOXC8 and HOXD11 genes are related to the tumor differentiation degree and regional lymph node metastasis, respectively. From siRNA assay, we found that HOXC8 and HOXD11 genes are essential for the expansion of FADU cell colonies. Our findings strongly suggest that members of the HOX family might be associated with the development of LSCC. Overall design: Twenty nine cancer samples and thirteen margin samples were collected from patients undergoing surgical ablation of LSCC according to Ethic Committee guideline and patient pre-informed signed consents. Whole human genome microarray analysis was applied to investigate new genetic targets in LSCC....
  13. Genes modulated by rhBMP2 and rhBMP7 during osteoblastic differentiation of C2C12 cells OmicsDI

    ID: E-GEOD-23783

    Date Released: 06-26-2012

    Description: . Moreover, we identified some new genes, such as Hoxc8, Glis1, Glis3, Ecsit, LrP6, Dvl1, Grn, BMP1, Ltbp2, Plod1, Htra1 and IGFBP-rP10, to be upregulated by both rhBMPs. Total RNA from mouse pre-myoblastic and pre-osteoblastic C2C12 cell line, after 12h of treatment with rhBMP2 and rhBMP7, was hybridized to a microarray and analyzed....

  14. Genes modulated by rhBMP2 and rhBMP7 during osteoblastic differentiation of C2C12 cells BioProject

    ID: PRJNA130723

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: . Moreover, we identified some new genes, such as Hoxc8, Glis1, Glis3, Ecsit, LrP6, Dvl1, Grn, BMP1, Ltbp2, Plod1, Htra1 and IGFBP-rP10, to be upregulated by both rhBMPs. Overall design: Total RNA from mouse pre-myoblastic and pre-osteoblastic C2C12 cell line, after 12h of treatment with rhBMP2 and rhBMP7, was hybridized to a microarray and analyzed....
  15. Transcription profiling of human keratinocytes to investigate non-invasive electric magnetic field effect on keratinocyte migration and proliferation ArrayExpress

    ID: E-GEOD-11181

    Description: rformed revealed increased expression of CRK7 and HOXC8 genes in treated keratinocytes. This study suggests that a non-invasive electric magnetic field accelerates wound reepithelialization through a mechanism of promoting keratinocyte migration and proliferation, possibly due to upregulation of CRK7 and HOXC8 genes. Experiment Overall Design: Non-invasive EMF: Experiment Overall Design: In this study, we used the Field Therapy Accelerator (FTA; Advatech, Miami, Florida) device to produce a magnetic field which in turn induces a non-invasive electric current in the target’s surroundings. All human and animal studies have been approved by the authors' Institutional Review Board. The FTA device generates a continuous series of direct current (DC)-like pulses of voltage followed for a very short time interval by a negative voltage spike. The induced EMF comprises of a series of concentric circles centered on the axis of the coil. The ...

  16. Transcription profiling of human keratinocytes to investigate non-invasive electric magnetic field effect on keratinocyte migration and proliferation OmicsDI

    ID: E-GEOD-11181

    Date Released: 05-02-2014

    Description: rformed revealed increased expression of CRK7 and HOXC8 genes in treated keratinocytes. This study suggests that a non-invasive electric magnetic field accelerates wound reepithelialization through a mechanism of promoting keratinocyte migration and proliferation, possibly due to upregulation of CRK7 and HOXC8 genes. Experiment Overall Design: Non-invasive EMF: Experiment Overall Design: In this study, we used the Field Therapy Accelerator (FTA; Advatech, Miami, Florida) device to produce a magnetic field which in turn induces a non-invasive electric current in the target’s surroundings. All human and animal studies have been approved by the authors' Institutional Review Board. The FTA device generates a continuous series of direct current (DC)-like pulses of voltage followed for a very short time interval by a negative voltage spike. The induced EMF comprises of a series of concentric circles centered on the axis of the coil. The ...

  17. Non-invasive electric magnetic fields: Effects on keratinocyte migration and proliferation BioProject

    ID: PRJNA106879

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: rformed revealed increased expression of CRK7 and HOXC8 genes in treated keratinocytes. This study suggests that a non-invasive electric magnetic field accelerates wound reepithelialization through a mechanism of promoting keratinocyte migration and proliferation, possibly due to upregulation of CRK7 and HOXC8 genes. Keywords: Comparative Genomic Hybridization Overall design: Non-invasive EMF: In this study, we used the Field Therapy Accelerator (FTA; Advatech, Miami, Florida) device to produce a magnetic field which in turn induces a non-invasive electric current in the target’s surroundings. All human and animal studies have been approved by the authors' Institutional Review Board. The FTA device generates a continuous series of direct current (DC)-like pulses of voltage followed for a very short time interval by a negative voltage spike. The induced EMF comprises of a series of concentric circles centered on the axis of the coil...

Displaying 17 of 17 results for "HOXC8"