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Displaying 14 of 14 results for "HOXB8"
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  1. Generation of hematopoietic progenitor cell lines with myeloid and lymphoid potential using a conditional form of Hoxb8 BioProject

    ID: PRJNA196179

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Generation of hematopoietic progenitor cell lines with myeloid and lymphoid potential using a conditional form of Hoxb8 ArrayExpress

    ID: E-GEOD-45759

    Description: . Here we show that an estrogen-regulated form of Hoxb8 that is retrovirally delivered into bone marrow cells can be used along with FLT3 ligand to conditionally immortalize early hematopoietic progenitor cells (Hoxb8-FL). Hoxb8-FL cells have lost self-renewal capacity and the ability to adopt megakaryocyte/ erythroid lineage fates, but sustain myeloid and lymphoid differentiation potential. Hoxb8-FL cells differentiate in vitr...

  3. Generation of hematopoietic progenitor cell lines with myeloid and lymphoid potential using a conditional form of Hoxb8 OmicsDI

    ID: E-GEOD-45759

    Date Released: 06-03-2014

    Description: . Here we show that an estrogen-regulated form of Hoxb8 that is retrovirally delivered into bone marrow cells can be used along with FLT3 ligand to conditionally immortalize early hematopoietic progenitor cells (Hoxb8-FL). Hoxb8-FL cells have lost self-renewal capacity and the ability to adopt megakaryocyte/ erythroid lineage fates, but sustain myeloid and lymphoid differentiation potential. Hoxb8-FL cells differentiate in vitr...

  4. HXB8_CHICK UniProt:Swiss-Prot

    ID: P23681

    Description: Homeobox protein Hox-B8 Homeobox Antp-type hexapeptide

  5. HXB8_PIG UniProt:Swiss-Prot

    ID: P09078

    Description: Homeobox protein Hox-B8 Homeobox

  6. HXB8_MOUSE UniProt:Swiss-Prot

    ID: P09632

    Description: Homeobox protein Hox-B8 Homeobox Antp-type hexapeptide

  7. HXB8_RAT UniProt:Swiss-Prot

    ID: P18863

    Description: Homeobox protein Hox-B8 Homeobox

  8. Identification of HOXB8 and K LK11 expression levels as potential biomarkers to predict the effects of FOLFOX4 chemotherapy BioProject

    ID: PRJNA286110

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. Identification of HOXB8 and K LK11 expression levels as potential biomarkers to predict the effects of FOLFOX4 chemotherapy OmicsDI

    ID: E-GEOD-69657

    Date Released: 01-01-2016

    Description: To measure global gene expression in primary advanced colorectal cancer patients who have undergone fluorouracil, leucovorin and oxaliplatin (FOLFOX4)...

  10. Identification of HOXB8 and K LK11 expression levels as potential biomarkers to predict the effects of FOLFOX4 chemotherapy ArrayExpress

    ID: E-GEOD-69657

    Description: To measure global gene expression in primary advanced colorectal cancer patients who have undergone fluorouracil, leucovorin and oxaliplatin (FOLFOX4)...

  11. The metabolic regulator mTORC1 controls terminal myeloid differentiation BioProject

    ID: PRJNA379153

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: KO mice, Tsc2 KO mice and controls; and 2) DR-ER-Hoxb8 cells differentiated in the presence of DMSO, rapamycin or SL0101-01...
  12. Gene expression patterns in response to IL-3 in human AML patient mononuclear cells OmicsDI

    ID: E-GEOD-51402

    Date Released: 02-24-2014

    Description: d transformation and AML. Using a murine model of HoxB8 and IL-3 cooperation we show that IL-3 modulates β-catenin protein levels, and Cre-induced deletion of β-catenin abolishes IL-3 dependent growth and colony formation. In the erythroleukemic cell line TF-1.8, we observed increased β-catenin protein levels and nuclear localization in response to IL-3, which correlated with transcriptional induction of β-catenin target genes. Furthermore, IL-3 promoted β-catenin accumulation in a subset of AML patient samples, and microarray gene expression analysis of these cells revealed induction of WNT/β-catenin and TCF4 transcriptional gene signatures in an IL-3 dependent manner. T...

  13. Gene expression patterns in response to IL-3 in human AML patient mononuclear cells ArrayExpress

    ID: E-GEOD-51402

    Description: d transformation and AML. Using a murine model of HoxB8 and IL-3 cooperation we show that IL-3 modulates β-catenin protein levels, and Cre-induced deletion of β-catenin abolishes IL-3 dependent growth and colony formation. In the erythroleukemic cell line TF-1.8, we observed increased β-catenin protein levels and nuclear localization in response to IL-3, which correlated with transcriptional induction of β-catenin target genes. Furthermore, IL-3 promoted β-catenin accumulation in a subset of AML patient samples, and microarray gene expression analysis of these cells revealed induction of WNT/β-catenin and TCF4 transcriptional gene signatures in an IL-3 dependent manner. T...

  14. Gene expression patterns in response to IL-3 in human AML patient mononuclear cells BioProject

    ID: PRJNA222925

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: d transformation and AML. Using a murine model of HoxB8 and IL-3 cooperation we show that IL-3 modulates β-catenin protein levels, and Cre-induced deletion of β-catenin abolishes IL-3 dependent growth and colony formation. In the erythroleukemic cell line TF-1.8, we observed increased β-catenin protein levels and nuclear localization in response to IL-3, which correlated with transcriptional induction of β-catenin target genes. Furthermore, IL-3 promoted β-catenin accumulation in a subset of AML patient samples, and microarray gene expression analysis of these cells revealed induction of WNT/β-catenin and TCF4 transcriptional gene signatures in an IL-3 dependent manner. T...

Displaying 14 of 14 results for "HOXB8"