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Displaying 18 of 18 results for "HLX"
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  1. Genes upregulated by HLX BioProject

    ID: PRJNA109971

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Identification of differentially regulated genes upon overexpression of HLX in wild-type hematopoietic stem cells BioProject

    ID: PRJNA141719

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Genes upregulated by HLX ArrayExpress

    ID: E-GEOD-13054

    Description: HLX was found as a VEGF-A induced gene in HUVEC (B.Schweighofer, submitted). In order to detect genes regulated by HLX

  4. Identification of differentially regulated genes upon shRNA-mediated knock-down of HLX in the URE leukemia cell line BioProject

    ID: PRJNA141721

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Genes upregulated by HLX OmicsDI

    ID: E-GEOD-13054

    Date Released: 06-02-2014

    Description: HLX was found as a VEGF-A induced gene in HUVEC (B.Schweighofer, submitted). In order to detect genes regulated by HLX

  6. Identification of differentially regulated genes upon overexpression of HLX in wild-type hematopoietic stem cells ArrayExpress

    ID: E-GEOD-27938

    Description: The goal was to study the role of Hlx in hematopoiesis. Sorted Lin-Kit+Sca-1+ cells from wild-type FVB/nJ bone marrow were infected with control (pCAD-IRES-GFP) or <...

  7. Identification of differentially regulated genes upon overexpression of HLX in wild-type hematopoietic stem cells OmicsDI

    ID: E-GEOD-27938

    Date Released: 09-24-2012

    Description: The goal was to study the role of Hlx in hematopoiesis. Sorted Lin-Kit+Sca-1+ cells from wild-type FVB/nJ bone marrow were infected with control (pCAD-IRES-GFP) or <...

  8. Identification of differentially regulated genes upon shRNA-mediated knock-down of HLX in the URE leukemia cell line OmicsDI

    ID: E-GEOD-27939

    Date Released: 09-24-2012

    Description: To study the role of Hlx in hematopoietic differentiation and tumorigenesis, URE cells were infected with short-hairpin-containing pSIH1-H1-copGFP lenti...

  9. Identification of differentially regulated genes upon shRNA-mediated knock-down of HLX in the URE leukemia cell line ArrayExpress

    ID: E-GEOD-27939

    Description: To study the role of Hlx in hematopoietic differentiation and tumorigenesis, URE cells were infected with short-hairpin-containing pSIH1-H1-copGFP lenti...

  10. HLX_RAT UniProt:Swiss-Prot

    ID: A0JPN1

    Description: H2.0-like homeobox protein Homeobox Pro-rich Poly-Gln Ser-rich

  11. HLX_BOVIN UniProt:Swiss-Prot

    ID: A7MB54

    Description: H2.0-like homeobox protein Homeobox Pro-rich Poly-Gln Ser-rich

  12. HLX_MOUSE UniProt:Swiss-Prot

    ID: Q61670

    Description: H2.0-like homeobox protein Homeobox Pro-rich Poly-Gln Ser-rich

  13. PAK1 is a Therapeutic Target in Acute Myeloid Leukemia and Myelodysplastic Syndrome ArrayExpress

    ID: E-GEOD-70791

    Description: inase (PAK1) as a downstream effector molecule of H2.0-like homeobox (HLX), a gene functionally relevant for AML pathogenesis. In this study, we find that inhibition of PAK1 activity by small molecule inhibitors or by RNA interference leads to profound leukemia-inhibitory effects both in vitro and in vivo. Inhibition of PAK1 induces differentiation...

  14. PAK1 is a Therapeutic Target in Acute Myeloid Leukemia and Myelodysplastic Syndrome OmicsDI

    ID: E-GEOD-70791

    Date Released: 08-20-2015

    Description: inase (PAK1) as a downstream effector molecule of H2.0-like homeobox (HLX), a gene functionally relevant for AML pathogenesis. In this study, we find that inhibition of PAK1 activity by small molecule inhibitors or by RNA interference leads to profound leukemia-inhibitory effects both in vitro and in vivo. Inhibition of PAK1 induces differentiation...

  15. PAK1 is a Therapeutic Target in Acute Myeloid Leukemia and Myelodysplastic Syndrome BioProject

    ID: PRJNA289538

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: inase (PAK1) as a downstream effector molecule of H2.0-like homeobox (HLX), a gene functionally relevant for AML pathogenesis. In this study, we find that inhibition of PAK1 activity by small molecule inhibitors or by RNA interference leads to profound leukemia-inhibitory effects both in vitro and in vivo. Inhibition of PAK1 induces differentiation...
  16. RAO miRNA : Serum miR-128 as a potential biomarker for asthma in horses BioProject

    ID: PRJEB20494

    Keywords: Other

    Access Type: download

    dataset.description: ing microRNAs in body fluids may act in a hormone-like manner and play important roles in disease initiation and progression. Hence, these microRNAs are promising candidates as biomarkers for many diseases. We aimed to identify serum microRNA biomarkers in the equine model of asthma. Small RNA derived from the serum of 35 co...
  17. Identification of novel transcriptional regulators involved in differentiation and function of monocyte and macropahge BioProject

    ID: PRJNA114803

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: sis further revealed novel genes (i.e. MEF2, BRI, HLX, HDAC5, H2AV, TCF7L2, NFIL3) previously uncharacterized to be involved in the differentiation process. A total of 58 selected genes representing cytokines, chemokines, surface antigens, signaling molecules and transcription factors were validated by real time PCR and compared to primary monocyte-derived macrophages. Beside the verification of several new genes, the comparison reveals individual heterogeneity of blood donors. Overall design: U937 cells were differentiated into monocytes by VitD3 (24 hrs) or into marophages by PMA (6 hrs, 12 hrs, 24 hrs and 32 hrs). Cells differentiated fo...
  18. NKL homeobox gene activities in hematopoietic stem cells, T-cell development and T-cell leukemia BioProject

    ID: PRJNA344440

    Keywords: Transcriptome or Gene expression

    Access Type: download


Displaying 18 of 18 results for "HLX"