HLA-DRA | bioCADDIE Data Discovery Index
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Displaying 20 of 77 results for "HLA-DRA"
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  1. The structure of HLA-DRA, DRB3*0101 (DR52a) with bound platelet integrin peptide associated with fetal and neonatal alloimmune thrombocytopenia PDB

    ID: PDB:2Q6W

    Description: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB3-1 beta ch...

  2. HLA-DR1 (DRA, DRB1 0101) HUMAN CLASS II HISTOCOMPATIBILITY PROTEIN (EXTRACELLULAR DOMAIN) COMPLEXED WITH ENDOGENOUS PEPTIDE PDB

    ID: PDB:1AQD

    Description: HLA-DR1 CLASS II HISTOCOMPATIBILITY PROTEIN, HLA-A2

  3. Structure of HLA-DR15 with bound alpha3(135-145) peptide PDB

    ID: PDB:5V4M

    Description: HLA-DRA1, alpha3(135-145)-HLA-DRB1*15:01

  4. CRYSTAL STRUCTURE OF HLA-DR2 (DRA*0101,DRB1*1501) COMPLEXED WITH A PEPTIDE FROM HUMAN MYELIN BASIC PROTEIN PDB

    ID: PDB:1BX2

    Description: PROTEIN (HLA-DR2)

  5. immune complex PDB

    ID: PDB:4Y1A

    Description: HLA-DRA, HLA-DRB1.0401, ProinsulinC19 , FS17_alpha, FS17_beta

  6. Structure of HLA-DR1 with bound alpha3(135-145) peptide PDB

    ID: PDB:5V4N

    Description: HLA-DRA1, alpha3(135-145)-HLA-DRB1*01:01

  7. immune complex PDB

    ID: PDB:4Y19

    Description: HLA-DRA, HLA-DRB1.0401, proinsulinC19, FS18_alpha, FS18_beta

  8. AIM2-responsive genes in colorectal tumor cells ArrayExpress

    ID: E-GEOD-24155

    Description: es (ISGs: IFIT1, IFIT2, IFIT3, IFI6, IRF7, ISG15, HLA-DRA, HLA-DRB, TLR3 and CIITA) as well as genes involved in intercellular adhesion and matrix remodeling. Expression of ISGs correlated with expression of AIM2 in ten different IFN-γ treated colorectal cancer cell lines. Moreover, knock-down of AIM2 resulted in reduced expression of HLA-DRA, HLA-DRB, and CIITA in IFN-γ treated cells. IFN-γ independent induction of HLA-DR genes and their encoded proteins was also demonstrated upon transient induction of AIM2. STAT-signaling was not involved in IFN-γ independent induction of...

  9. Transcriptional effects of 1,25 dihydroxi-vitamin D3 physiological and supra-physiological concentrations in breast cancer organotypic culture ArrayExpress

    ID: E-GEOD-27220

    Description: scripts were members of the MHC class II complex (HLA-DPA1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3) and IgG binding (FCGR2A, FCGR2B, FCGR2C). There was an enrichment of genes presenting transcription factor binding sites for vitamin D, among the up-regulated genes and for interferon regulatory factor IRF1, among the down-regulated genes. Analyzing calcitriol supra-physiological effects, a more impressive transcriptional modulation was identified and 136 and 60 genes (FDR 0.1) were more and less expressed in treated samples. Up-regulated genes were involved in vitamin metabolic process, regulation of leukocyte-mediated immunity and positive regulation of alpha-beta T cell activation. Many of the induced genes were already reported as vitamin D responsive genes, including CD14, which was also up-regulated in another set of 16 samples. Genes modulated by both calcitriol concentrations were CYP24A1, DPP4, CA2 (these three in both sets of samples), EFTUD1, TKTL1, KCNK3. Conclusio...

  10. AIM2-responsive genes in colorectal tumor cells OmicsDI

    ID: E-GEOD-24155

    Date Released: 01-14-2013

    Description: es (ISGs: IFIT1, IFIT2, IFIT3, IFI6, IRF7, ISG15, HLA-DRA, HLA-DRB, TLR3 and CIITA) as well as genes involved in intercellular adhesion and matrix remodeling. Expression of ISGs correlated with expression of AIM2 in ten different IFN-γ treated colorectal cancer cell lines. Moreover, knock-down of AIM2 resulted in reduced expression of HLA-DRA, HLA-DRB, and CIITA in IFN-γ treated cells. IFN-γ independent induction of HLA-DR genes and their encoded proteins was also demonstrated upon transient induction of AIM2. STAT-signaling was not involved in IFN-γ independent induction of...

  11. AIM2-responsive genes in colorectal tumor cells BioProject

    ID: PRJNA130041

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: es (ISGs: IFIT1, IFIT2, IFIT3, IFI6, IRF7, ISG15, HLA-DRA, HLA-DRB, TLR3 and CIITA) as well as genes involved in intercellular adhesion and matrix remodeling. Expression of ISGs correlated with expression of AIM2 in ten different IFN-γ treated colorectal cancer cell lines. Moreover, knock-down of AIM2 resulted in reduced expression of HLA-DRA, HLA-DRB, and CIITA in IFN-γ treated cells. IFN-γ independent induction of HLA-DR genes and their encoded proteins was also demonstrated upon transient induction of AIM2. STAT-signaling was not involved in IFN-γ independent induction of...
  12. X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus DNA polymerase. PDB

    ID: PDB:1H15

    Description: HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR BETA 1 CHAI...

  13. Crystal structure of an immune complex at pH 6.5 PDB

    ID: PDB:4GBX

    Description: HLA class II histocompatibility antigen, DM alpha chain, HLA class II histocompatibility antigen, DM beta chain,...

  14. Crystal structure of HLA-DM bound to HLA-DR1 PDB

    ID: PDB:4FQX

    Description: HLA class II histocompatibility antigen, DM alpha chain, HLA class II histocompatibility antigen, DM beta chain,...

  15. F54C HLA-DR1 bound with CLIP peptide PDB

    ID: PDB:3QXD

    Description: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta ch...

  16. Crystal structure of CD4 mutant bound to HLA-DR1 PDB

    ID: PDB:3S5L

    Description: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta ch...

  17. Structure of human MHC class II protein HLA-DR1 carrying an influenza hemagglutinin peptide partially filling the binding groove PDB

    ID: PDB:4I5B

    Description: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta ch...

  18. Crystal Structure of HLA-DR1 with CLIP106-120, flipped peptide orientation PDB

    ID: PDB:3PGC

    Description: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta ch...

  19. HLA-DR1 bound with CLIP peptide PDB

    ID: PDB:3QXA

    Description: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta ch...

  20. Crystal Structure of HLA-DP2 PDB

    ID: PDB:3LQZ

    Description: HLA class II histocompatibility antigen, DP alpha 1 chain, HLA-DP2 beta chain linked with DRa...


Displaying 20 of 77 results for "HLA-DRA"